Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"neutral sphingomyelinase"”.
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iPLA2β, ALTERNATIVE SPLICING AND APOPTOSIS OF PANCREATIC ISLETS
… A recent study demonstrated that expression of neutral sphingomyelinase (NSMase), an enzyme that hydrolyzes sphingomyelins to generate ceramide, is regulated by Group VIA phospholipase A2 (iPLA2β)-dependent mechanism during β-cell apoptosis. This prompted us to hypothesize that iPLA2 is upstream …
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Sphingomyelinases and Lysosomal Trafficking in Ebolavirus Entry
… During lysosomal exocytosis, pH-dependent acid sphingomyelinase (ASM) is released to the plasma membrane‟s outer leaflet, resulting in ASM-dependent macropinosome formation. Because EBOV enters via a macropinocytosis-like mechanism, the role of ASM in infection was assessed. Specific ASM …
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Exploring the roles of key lipids in the influenza virus lifecycle
The influenza virus is a common respiratory pathogen with the capacity to cause global pandemics affecting millions of people, contributing substantially to overall mortality and morbidity. Thus, considerable research focuses on the prevention and treatment of influenza virus infection. Despite the …