NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 20 of 40 for “"neurotransmitter systems"”.

  1. Investigation of Monoaminergic Neurotransmitter Systems as a Method to Study Alzheimer's Disease-Related Neurodegeneration

    Gallardo, Christopher2018

    … analyses of brainstem monoaminergic (MAergic) systems in the APPSwe/PS1ΔE9 was the first to show that Aβ pathology could induce progressive neurodegeneration in vivo [23]. Subsequent studies expanded on these observations showing degeneration initiating at axon terminals and progressing to cell …

    umn Repository record

  2. Treatment During Abstinence from Methamphetamine in a Rat Model of Methamphetamine Use Disorder

    Baek, James Jaewoo2022

    … with changes to the dopamine and glutamate neurotransmitter systems, as well as inflammation. Phosphodiesterase-4 inhibitors are known to affect cAMP involved in dopaminergic and glutamatergic neurotransmission, as well as having anti-inflammatory action. In pre-clinical models, …

    iupui Repository record

  3. Habit Formation in a Rodent Model of Alcoholism: Genetic Susceptibility, Alcohol-Specific Effects, and Pharmacological Manipulation

    O'Tousa, David Scott

    … toward lower neurological mechanisms. While many neurotransmitter systems have a demonstrated involvement in this process, the dopamine system is particularly implicated. Habit formation is assessed through the maintenance of extinction responding for an undesired, or devalued, outcome.

    purdue-thes Repository record

  4. Cortical Eeg Following Bilateral Lateral Hypothalamic Damage: Effects of Drugs Acting on Some Components of the Reticular Formation (Hippocampus, Animal-Model, Pharmacology)

    Shoham, ShaiUniversity of Illinois at Urbana-Champaign2014

    … normal rat does, may reflect disruption of some neurotransmitter components of the reticular formation known to contribute to cortical LVF-activation. The purpose of this investigation was to find whether drugs which enhance or mimic the action of these reticular neurotransmitter systems …

    uiuc Repository record

  5. Effects of nicotine on content of corticotropin releasing factor (CRF) in rat amygdala, hypothalamus and brain stem

    Masilela, Sibonisiwe Ntini2019

    … to stress, fear and anxiety, influences the same neurotransmitter systems as nicotine, a psychoactive component of tobacco. Radioimmunoassays revealed that in macro-dissected hypothalami, 15 minutes treatment with 1.0 mg/kg nicotine significantly increased CRF content compared to no treatment. The …

    wvu Repository record

  6. Investigation of Carbamathione Pharmacokinetics and Pharmacodynamics by In Vivo Microdialysis and Capillary Electrophoresis

    Kaul, SwethaUniversity of Kansas2010

    … receptor. The effect of carbamathione on the neurotransmitter systems involved in craving and addiction is unknown. The aim of this research project was to develop analytical methods to determine carbamathione and relevant neurotransmitters in rat brain microdialysis samples in order to …

    ku Repository record

  7. Neurochemical Mechanisms in the Hypothalamus and Attenuation of Compensatory Hormone Responses to Recurrent Hypoglycemia

    De Vries, Martin GoosUniversity of Illinois at Urbana-Champaign2015

    … recurrent hypoglycemia. Moreover, noradrenergic neurotransmitter systems in the hypothalamus are activated to a decrease in ambient glucose, and their responsiveness is preserved after recurrent daily hypoglycemic episodes on three consecutive days. From the present work it became evident that …

    uiuc Repository record

  8. INTRACRANIAL INFUSIONS OF NEUROTENSIN AGONISTS PRODUCE AN ANXIOLYTIC PROFILE IN A RAT ULTRASONIC VOCALIZATION MODEL

    Steele, Floyd F, III2015

    <p>Neurotensin (NT) is a peptide neurotransmitter that interacts with brain monoamine neurotransmitter systems. It has been demonstrated that neurotensin type 1 and type 2 receptor agonists influence animal models of psychological disorders and pain regulation, respectively. It has already been …

    nmu Repository record

  9. Genomic and non genomic effects of elevated concentration of anabolic steroids in human neuronal cells

    Guarino, Goffredo <1979>Alma Mater Studiorum - Università di Bologna2008

    … can alter the expression and function of neurotransmitter systems and contribute to neuronal cell death. This effect can explain the behavioural changes, drug dependence and neuro degeneration observed in steroid abuser. Nandrolone treatment (10-8M–10-5M) caused a time- and …

    bologna Repository record

  10. Molecular bases of scouting behavior in honey bees

    Liang, ZhengzhengUniversity of Illinois at Urbana-Champaign2013

    … dopaminergic, octopaminergic and glutamatergic systems. I found significant brain down- regulation of the D1-type dopamine receptor genes and upregulation of the octopamine receptor genes in scouts compared to non-scouts. Microarray analysis confirmed these findings and further implicated …

    uiuc Repository record

  11. Astrocytic Contribution to the Glutamatergic Transmission in Schizophrenia

    Stan, Ana Despina2011

    … exists for abnormalities within all the main neurotransmitter systems and various cortical and subcortical brain structures, albeit with no unifying/overarching hypothesis connecting the existent knowledge. Moreover, no current animal model or biological construct reproduces the complexity of …

    utswmed Repository record

  12. Opiate Regulation of Lordosis: Neurochemical Evaluation of the Role of Opiate-Serotonergic Interactions

    Allen, Donald LeRoy

    … of lordosis, and to examine the role of other neurotransmitter systems in the actions of opiates. The opiate antagonist naltrexone was found to facilitate lordosis in estrogen-primed rats. Naltrexone facilitated behavior was compared to the facilitation of behavior by progesterone. The medial …

    rockefeller Repository record

  13. Regulation of dorsal raphe serotonergic neurons by histamine

    Panetta, Kara MarieUniversity of Dundee2014

    … cycle results from the complex interaction of neurotransmitters systems, which arise from anatomically and chemically defined brain structures. Serotonergic neurons located in the dorsal raphe nucleus (DRN) are currently accepted to be wake-promoting however their precise regulation by other …

    dundee Repository record

  14. Investigating the neurobiology regulating cognitive effort allocation using a rodent model of cost/benefit decision making

    Silveira, Mason2018

    … literature investigating the brain regions and neurotransmitter systems guiding these respective forms of decision making, and then carries out a set of experiments to further characterize the neurobiology guiding cognitive effort allocation. These experiments utilize an animal model of decision …

    arts-london Repository record

  15. Functional Organization and Information Processing Within the Suprachiasmatic Nucleus Assessed by Multiunit Recording in Vitro

    Tcheng, Thomas KimUniversity of Illinois at Urbana-Champaign2015

    … drugs was used to test several of the classical neurotransmitter systems present in the SCN. Most treatments elicited both excitatory and inhibitory responses (during separate trials). The majority of MUA responses to pharmacological treatments were consistent with the expected direct effects of …

    uiuc Repository record

  16. Striatal Dopamine Dynamics Upon Manganese Accumulation

    Khalid, Madiha2013

    … is observed, indicating the involvement of other neurotransmitter systems in the onset of motor deficits following Mn exposure. Finally, by methodically evaluating the quantity and functionality of dopamine vesicles at the axon terminal, we were able to provide evidence against the theory that …

    wayne-thes Repository record

  17. The Role of CLOCK in Regulation of Dopamine Neurotransmission in the CLOCKdelta19 Mutant Mouse Model

    Spencer, Sade Monique2012

    … significant cross-talk with many of the brain’s neurotransmitter systems. The purpose of this dissertation is to characterize the role of CLOCK in regulating dopamine transmission in mood and reward-related circuits. We present a mechanism by which CLOCK regulates dopaminergic activity in the …

    utswmed Repository record

  18. Role of the Serotonin (5-HT) 5-HT2C Receptor (5-HT2CR) in Cocaine Cue Reactivity

    Jackson, SarahThe University of Texas Medical Branch at Galveston2020

    … outcomes and extend abstinence. Serotonin (5-HT) neurotransmitter systems play an important role in the behavioral effects of cocaine particularly through the 5-HT2C receptor (5-HT2CR), however, the involvement of this system in incubation of cue reactivity during abstinence from cocaine …

    utmb Repository record

  19. INDIVIDUAL DIFFERENCES IN IMPULSIVE ACTION AND TEMPORAL ESTIMATION: INTERACTION WITH THE SEROTONIN (5-HT) 5-HT2A RECEPTOR

    Fink, Latham Henry LeedsThe University of Texas Medical Branch at Galveston2021

    … pathways (e.g., prefrontal cortex, PFC) and neurotransmitter systems (e.g., serotonin, 5-HT) that regulate impulsive action. Manipulation of the 5-HT2A receptor (5-HT2AR) influences impulsive action and timing functions, suggesting that functional capacity of the 5-HT2AR system may drive the …

    utmb Repository record

  20. Role of the Serotonin (5-HT) 5-HT2C Receptor (5-HT2CR) in Cocaine Cue Reactivity

    Jackson, SarahThe University of Texas Medical Branch at Galveston2020

    … outcomes and extend abstinence. Serotonin (5-HT) neurotransmitter systems play an important role in the behavioral effects of cocaine particularly through the 5-HT2C receptor (5-HT2CR), however, the involvement of this system in incubation of cue reactivity during abstinence from cocaine …

    utmb Repository record

Page 1 of 2