NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 20 of 94 for “"neurotoxin"”.

  1. Studies on a Neurotoxin From Lathyrus Sativus

    Mehta, TaraUniversity of Illinois at Urbana-Champaign2015

    Made available in DSpace on 2015-05-12T22:36:28Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7317326.PDF: 7208374 bytes, checksum: fb89cb27f314ec84f8c8bc785f994137 (MD5) Previous issue date: 1972

    uiuc Repository record

  2. Understanding the Fate of the Neurotoxin Domoic Acid In Coastal Systems

    Burrell, Christopher Thomas

    <p>The elderly club program (ECP), a community-based intervention, has been implemented to support self-help organizations and promote the health and quality of life of seniors in Thailand. Due to dramatic increases in aging populations, it is important to determine whether or not the club …

    south-carolina Repository record

  3. Engineering functional recombinant proteins based on antibody domains and fragments of C. botulinum neurotoxin

    Tolkacz, JOxford Brookes University2010

    … single domain antibodies. Recombinant botulinum neurotoxin fragments derived from serotype A, B, C and D are selected as backbones for an investigation into the feasibility and properties of novel recombinant targeted multidomain proteins. Single chain Fv’s consist of a VH region of heavy chain …

    oxford-brookes Repository record

  4. Studies on the monoamine oxidase substrate/inactivator properties of piperidine analogs of the neurotoxin MPTP

    Chi, FengVirginia Tech1996

    The unexpected monoamine oxidase (MAO) substrate properties of 1-cyclopropyl-4-substituted-1 ,2,3,6-tetrahydropyridines have been interpreted in terms of partitioning of these tertiary cyclic allylamines between substrate turnover and ring opening inactivation processes. To evaluate further this …

    vt Repository record

  5. Real-time PCR for diagnosis of botulism and quantification of neurotoxin gene expression in Clostridium botulinum

    Artin, IngridDivison of Medical Microbiology2008

    … and (ii) monitoring the expression of the neurotoxin gene, cnt, during different growth phases and under different growth conditions. For the diagnosis of botulism, a real-time PCR-based method including an internal amplification control for C. botulinum types A, B and E was developed. The …

    lund Repository record

  6. Nutrient Controls Over Cyanobacterial Synthesis of the Neurotoxin β-N-Methylamino-L-Alanine (BMAA) and Its Potential Accumulation in the Blue Crab (<i>Callinectes Sapidus</i>)

    Hummel, Madeline M.2019

    <p>Cyanobacteria are known to produce a variety of toxins that negatively impact both aquatic and terrestrial organisms. One putative neurotoxic compound is the non-protein amino acid β-N-methylamino-L-alanine (BMAA), which has epidemiological linkages to the development of several human …

    odu Repository record

  7. Thermodynamic Evidence That Ganglioside-Mediated Insertion Of Botulinum A Into The Cholinergic Nerve Ending May Precede Endocytosis And Acidification: A Langmuir Film Study

    Strongin, Bradley Adam2007

    Botulinum Neurotoxin (BoNT) is one of the most potent toxins known to human kind. The Atomic Force Microscope (AFM) was employed to investigate the conditions under which BoNT type A heavy chain would bind and/or insert into mica supported dipalmitoylphosphatidylcholine (DPPC) lipid bilayers. As an …

    byu Repository record

  8. A Novel Role for and Potential Therapeutic Targeting of Heme Oxygenase-1 in HIV Neuropathogenesis

    Gill, Alexander Julian2015

    … glutamate. This HO-1 deficiency and associated neurotoxin production was a conserved feature of infection with macrophage-tropic HIV-1 and HIV-2 strains that correlated closely with the extent of replication. ART regimens applied to macrophages after HIV infection was established failed to …

    penn Repository record

  9. Exercise induced neuroprotection in spontaneuosly running rats

    Mabandla, Musa VuyisileDepartment of Human Biology2007

    … immobilised). Two weeks after injection of the neurotoxin, the rats were injected with apomorphine and the number of ipsilateral and contralateral rotations was counted with contralateral rotations of greater than 150 considered to represent striatal dopamine neuron destruction of 70% or above.

    cape-town Repository record

  10. Tick toxinology : isolation and characterisation of the toxin from the Australian paralysis tick, Ixodes holocyclus

    Thurn, MJ1994

    … species of ticks have been reported to secrete neurotoxins which can be fatal to mammals, including man. Envenomation by the Australian paralysis tick, I. holocyclus, is a considerable veterinary problem affecting tens of thousands of domestic and native animals each year. Envenomation is …

    uts Repository record

  11. Genetic Intervention in Sensory Systems of a Fly

    Keller, AndreasUniversität Würzburg

    … um diese abzutöten oder zu blockieren. Tetanus Neurotoxin erwies sich als sehr effizient, um chemische Synapsen zu blockieren. Synapsen, die aus einer chemischen und einer elektrischen Komponente bestehen, ließen sich dagegen mit einem ektopisch exprimierten humanen Kalium-Kanal zuverlässiger …

    wurz-thes Repository record

  12. Low-Cost and High-Throughput Optofluidic Add-on Device for Light Sheet Imaging of Larval and Adult C. Elegans

    Rahimpouresfahani, Faraz2024

    … worms, as well as in analyzing control and neurotoxin-exposed worms. Additionally, we utilized a new transgenic worm model for Parkinson's disease and were able to detect a fluorescence difference between larval and adult stages. The result is a vast dataset of high-content images that will …

    york Repository record

  13. The synthesis and pharmacology of novel excitatory amino acid mimetics

    Joseph, M.City of London Polytechnic1984

    … acid (Quin), an endogenous excitant and neurotoxin, may be classified as an NMDA type compound. The aim of this project has been to develop analogues of Quin, some of which may well be specific antagonists of NMDA. The higher homologue (1) of Quin has been s3rnthesised and has very …

    london-metro Repository record

  14. An Avian Botulism Epizootic Affecting a Nesting Site Population of Presbyornis : on a Carbonate Mudflat Shoreline of Eocene Fossil Lake

    Leggitt, V. Leroy

    … avian death with <em>Clostridium botulinum</em> neurotoxin in the paleontologic literature.</p> <p>At this <em>Presbyornis </em>site, two distinct mass mortality events are evident. The first event (lowest in the section) is a widespread aquatic gastropod mortality with localized eggshell and a …

    loma-linda Repository record

  15. Impact of strain variability on the risk presented to chilled foods by non-proteolytic clostridium botulinum

    Wachnicka, EwelinaUniversity of East Anglia2014

    … chill temperatures and variability in growth and neurotoxin formation in the presence of different carbohydrates. A strain classification pattern was developed and compared with published literature information on the genetic variation of non-proteolytic C. botulinum. Results for the growth at …

    east-anglia Repository record

  16. STRUCTURE, FUNCTION AND FOLDING OF THREE FINGER TOXINS

    PUDUR VENKATESWARULU DILEEP KUMAR2021

    … activities. Our group characterized Oh9-1, a neurotoxin from venom of Ophiophagus hannah. Although Oh9-1 binds to the same acetylcholine binding pocket as the -neurotoxins, it lacks key functional residues. In this thesis, I describe the three-dimensional structure of Oh9-1 by NMR. Unlike the …

    nus Repository record

  17. THREE-FINGER TOXINS AS SELECTIVE PROBES TO DISTINGUISH SUBUNIT INTERFACES OF NICOTINIC ACETYLCHOLINE RECEPTORS

    CHAN YUE LING, CHRISTABEL2024

    … are a major family of snake toxins, containing ?-neurotoxins and ?-neurotoxins that selectively antagonize postsynaptic nicotinic acetylcholine receptors (nAChRs). For the first time, the cryo-EM structure of a natural ?-neurotoxin, Erabutoxin-A (Ea), complexed with Tetronarce californica nAChR …

    nus Repository record

  18. Insights Into Particulate Phosphorus Dynamics and toxic Algal Bloom Events From A 13-Year Sediment Trap Study In Santa Barbara Basin (CA)

    Wood, Emily Sekula

    … genus Pseudo-nitzschia, which can produce the neurotoxin domoic acid (DA) and has been responsible for numerous marine mammal and bird mortalities on the West Coast of the U.S. The goal of this dissertation is to examine particulate P cycling, Pseudo-nitzschia blooms, and DA export using a …

    south-carolina Repository record

  19. Enhanced NMR Detection of Mass -Limited Samples With Microcoil Probes: Increasing Sample Throughput and Improved on-Line Coupling to Microscale Separations

    Wolters, Andrew MarkUniversity of Illinois at Urbana-Champaign2015

    … Also benefiting natural product studies, a neurotoxin extracted from a marine organism has been characterized by cITP/NMR. Application of microcoil NMR detection to other separation methods, such as capillary liquid chromatography, will be presented.

    uiuc Repository record

  20. Elemental and reactive gaseous mercury deposition and diurnal cycles over terrestrial environments

    Maheras, Anastasia FrancisMassachusetts Institute of Technology2011

    … a simple one-box model. Mercury is a significant neurotoxin for humans and other species that has been addressed in the policy realm on both national and international levels. Being able to model atmospheric mercury processes correctly is an important part of regulation and policy drafting. …

    mit Repository record

Page 1 of 5