Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"neuropilins"”.
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Rational Identification of Neuropilin-1 Inhibitors: From Deep-Learning to Drug Repurposing
Neuropilins (NRP)—comprising neuropilin-1 (NRP1) and neuropilin-2 (NRP2)—are type I transmembrane glycoproteins with multifunctional extracellular regions. NRP1 functions as a multifunctional, non-enzymatic co-receptor that potentiates signalling from vascular endothelial growth factor (VEGF), …
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Quantitative analysis of neuropilin-2 expression in pigmented lesions and melanoma
… of a primary melanoma and ultimately metastasis. Neuropilins, specifically Neuropilin-2 (NRP2), have been found to be associated with both angiogenesis and lymphangiogenesis and thus metastasis. Since it is critical to identify and treat melanoma before it advances to metastasis, the relationship …
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Effekte der Klasse-3 Semaphorine auf die Entwicklung und Progression maligner Hirntumoren
Neuropiline gehören zu den endothelialen Oberflächenrezeptoren und agieren als Rezeptoren für angiogene Faktoren aus der Familie der VEGF-Familie (vascular endothelial growth factor). Daneben spielen sie als Rezeptoren für Faktoren der Axon-Orientierung aus der Klasse-3-Semaphorin-Subfamilie eine …