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Showing 1 to 20 of 59 for “"neuropeptide Y"”.
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Effects of Neuropeptide Y on Adipocyte Metabolism
Recently, we have shown that neuropeptide Y (NPY) is produced and upregulated in visceral adipose tissue of an early-life programmed rat model of central obesity. Moreover, we have demonstrated that NPY contributes to the pathogenesis of obesity. However, the role of NPY in regulating adipocyte …
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Folding, dynamics and interaction studies of the Neuropeptide Y family.
… advance the treatment of human disease. The Neuropeptide Y family of peptides are highly conserved peptides found in nature, consist of 36 amino acids, and are widely distributed in the central nervous system of mammals. A detailed study of thermodynamics, kinetics, membrane translocation, …
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Exploring relationships between stress and olfaction as mediated by neuropeptide y
… and resilience to stress, specifically examining neuropeptide y (NPY) as a mediator. In phase I, 197 UTC students participated in a survey measuring stress and resilience among other factors. Of this sample, 25 students volunteered for phase II, in which they took an olfactory threshold test and …
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The Role of Neuropeptide Y Y1R in Skeletal Muscle Lipid Metabolism
The Hulver laboratory has recently found that the neuropeptide Y Y1 receptor (NPY Y1R) mRNA expression is elevated in skeletal muscle of obese humans (Hulver, unpublished). The goal of this research is to study the role of the NPY Y1R in skeletal muscle lipid metabolism. Rat L6, mouse C2C12, and …
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Regulation of the suprachiasmatic circadian pacemaker by serotonin and neuropeptide Y in vitro
Made available in DSpace on 2011-05-07T14:27:17Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9543662.pdf: 4374167 bytes, checksum: 07d9da4452632e2043ead8592edaf5e2 (MD5) Previous issue date: 1995
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Dietary macronutrient composition and exogenous neuropeptide Y affect feed intake in brioler chicks
… States. Central appetite regulators, known as neuropeptides, are pivotal in understanding appetite regulation. Neuropeptide Y (NPY), a 36 amino acid peptide, plays a major role in regulating the hunger signals from the brain. In all vertebrates studied, it is a strong orexigenic …
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Endogenous modulators of hyperexcitability in epilepsy: electrophysiological and optogenetic delineation of neuropeptide Y mechanisms in interneurons
… for therapeutic intervention. Among these, neuropeptide Y (NPY ) seems to be a particularly promising target, as it plays an important role in controlling neuronal excitability in different brain areas, including the hippocampus. Indeed, overexpression of NPY via gene therapy approaches in …
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Effects of dietary macronutrient composition and exogenous neuropeptide Y on adipose tissue development in broiler chicks
… effect of dietary macronutrient composition on neuropeptide Y (NPY)-mediated regulation of adipose tissue physiology in broiler chickens during the early post-hatch period. A high-carbohydrate (HC), high-fat (HF) or high-protein (HP) diet was fed to broiler chicks in all experiments and various …
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60 Hz magnetic field exposure inhibits protein Kinase C dependent induction of Neuropeptide Y mRNA in PC-12 cells
The effects of MF exposure on the chemically induced production of NPY mRNA in the rat pheochromocytoma, PC-12 cell line.
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60 Hz magnetic field exposure inhibits protein Kinase C dependent induction of Neuropeptide Y mRNA in PC-12 cells
The effects of MF exposure on the chemically induced production of NPY mRNA in the rat pheochromocytoma, PC-12 cell line.
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Investigating the Role of Neuropeptide Y in the Ventral Hippocampus in Regulating Rats’ Elevated Plus-Maze and Shock-Probe Burying Behaviours
Neuropeptide Y (NPY) has recently gained interest as a potential regulator of anxiety-like behaviours. However, its anxiety-associated effects in the ventral hippocampus are not well known, even though this structure is also heavily implicated in anxiety regulation. The goal of this thesis was to …
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Regulation of Neuropeptide Y, Vasoactive Intestinal Polypeptide, and Their Receptors in Trigeminal Ganglion Neurons and Glia in Response to Adjuvant-Induced Inflammation
… joint (TMJ) inflammation and pain transmission. Neuropeptide Y (NPY), vasoactive intestinal polypeptide (VIP), and their receptors have been implicated in the underlying pathology of temporomandibular joint disorders. The goal of this study was to investigate activation of NPY, VIP, and their …
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Appetite Regulatory Neural Circuitry in the Prenatal Testosterone Treated and Obese Ewe
… express both agouti-related protein (AgRP) and neuropeptide Y (NPY), or proopiomelanocortin (POMC) and cocaine- and amphetamine- regulated transcript (CART). We then asked whether this circuitry is altered in ewes at increased risk of obesity following prenatal testosterone (T) treatment, or in …
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Central mechanisms of prolactin-releasing peptides orexigenic effect in chickens
… peptide (PrRP) is an endogenous hypothalamic neuropeptide that when exogenously injected increases food intake in chickens, but decreases it in rodents and goldfish. We designed three sets of experiments to elucidate the mechanisms of PrRP's orexigenic effect in chicks. In experiment one, food …
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Thioamides And Proteolysis: Examining The Effects And Applications Of A Single-Atom Substitution
… that is known to selectively bind to the neuropeptide Y Y1 receptor increased its serum stability, without affecting its affinity for the receptor. Currently, we are optimizing this stabilized imaging peptide usage in animals by changing linkers, fluorophores, and N-terminal modifications. …
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Novel hypothalamic G protein-coupled receptors involved in the control of reproduction
… were identified; oxytocin receptor (OXTR) and Y4 neuropeptide Y receptor (NPY4R). Both receptors have been shown to have a role in reproduction, however, mutations in neither have been previously implicated in causing KS/nCHH respectively. The aim was to determine whether identified mutations in …
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Changes in NPY staining in the arcuate nucleus during and after food restriction in lactating rats
… investigated the effects of food restriction on Neuropeptide Y (NPY) staining in the arcuate nucleus of lactating rats to evaluate a role for NPY in the maintenance of lactational diestrus in food restricted rats. NPY staining was compared on days 15, 20 and 25 of lactation between animals fed ad …
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