Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"neuronal projections"”.
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Graded lines: using genetic variation in neuronal projections to understand functional organization
In this thesis, I investigated the interactions between brain regions in mice, with an emphasis on the motor system. Whilst brain areas are typically studied in isolation, they exist to act upon one other, and we lack even relatively basic principles of how brain areas interact. Here, my colleagues …
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Understanding Huntington's Disease pathogenesis using next generation sequencing analyses
… of the localization of mRNA transcripts to neuronal projections can be studied by combining fractionation experiments with RNA-Seq. A method to prepare high quality RNA from isolated neuronal projections was developed and is now applicable to RNA-Seq studies.
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Eph-Ephrin Signaling and the Role of EFN-4 in Caenorhabditis Elegans Nervous Systems Development
… in cell-to-cell communications that guide AIY neuronal projections.</p>
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Grey matter morphological changes in late life using magnetic resonance imaging technique
… to the hippocampus by virtue of cholinergic neuronal projections. Structural neuroimaging studies have shown reduced volumes of both structures in mild cognitive impairment (MCI); however, of interest is the understanding of how the two structures work together to influence the diagnosis of …
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The Role of Drosophila Odorant Receptors in Odor Coding
… we assembled maps of the olfactory neuron projections in the fly brain and characterized the contribution of several ORs to olfactory-guided behavior. We compiled near-complete maps of OR-specific neuronal projections to the antennal lobe glomeruli of adult and larval fly brains. We …
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Roles for cell surface glycans in guiding human pluripotent stem cell fate
… on HS. Moreover, lack of HS hinders the proper neuronal projections and synaptic vesicle formation in hPS cell-derived neurons, suggesting a specific role of HS in human neural development. Taken together, these results indicate that HS has a highly dynamic ultrastructure that modulates cell …
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Synapse Formation in the Zebrafish Lateral Line
… the zebrafish lateral line. First, I examine the neuronal architecture of the neuromast at nanometer-scale resolution by imaging the tissue by serial block-face electron microscopy. The data demonstrate that afferent neurons show a polarity preference at the earliest stages of hair-cell …