Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 19 of 19 for “"neuron number"”.
-
Genetic Analysis of Variation in Neuron Number
<p>There are large differences in neuron number both within and between species. This variation in neuron number results from both non-genetic and genetic factors. Non-genetic factors, such as litter size and parity, and genetic cofactors, such as sex, age, and body weight, can influence neuron …
-
Developmental Cell Death and Androgens Affect Neuron Number in the Primary Visual Cortex of Male and Female Rats
Finally, I investigated the effect of neonatal hormone manipulations (females + estradiol, females + DHT) upon cell death in the developing rat posterior cortex. DHT implantation in females decreased the proportion of cells dying relative to control females (similar to control males), while …
-
Structure of the Rat Medial Prefrontal Cortex Is Influenced by Sex Across the Lifespan
… and aging of sex differences in the volume, neuron number and glial cell number in the mPFC, as well as frontal white matter volume, were also examined in both sexes using unbiased stereological techniques. Ventral rat mPFC gray matter volume increased prior to puberty and then decreased …
-
Lifespan Changes, Sex Differences, and Hormone Effects in the Primary Visual Cortex of the Rat and the Associated Area of the Corpus Callosum, the Splenium
… in Oc1 and the splenium. Examination of neuron number in aged animals (19-22 months) found that Oc1 was significantly impacted during aging, with both males and females losing neurons (18-20%) between day 90 and old age, maintaining the sex differences in neuron number. However, …
-
Effects of long-term hormone treatment on cognitive behavior and the structure of the medial prefrontal cortex during aging in female rats
… Nissl stained to calculate volume and quantify neuron number. The medial prefrontal cortex was examined because it is involved in several cognitive tasks and is known to be sensitive to both aging and ovarian hormones. Using unbiased stereology and light microscopy, neuron number and …
-
Molecular and Neural Mechanisms Underlying Courtship Song Evolution in Drosophila
… is encoded by evolutionary changes in genes and neurons is unclear. To fill in this knowledge gap, my colleagues and I take advantage of the diversification of Drosophila courtship songs as a model system to explore the molecular and neural mechanisms underlying species variation in behavior. We …
-
Age sensitivity of the Barnes Maze and the Morris Water Maze: Associations with cerebellar cortical Purkinje neurons
… anatomy across the life span (loss of Purkinje neurons), this study evaluated these behavioral tests in terms of sensitivity to both age-related changes in learning as well as age-related changes in the cerebellar cortex. A total of 65 CB6F1 mice were tested at one of five ages (4, 8, 12, 18, or …
-
Identification and Characterization of the Neurotrophic Properties of Dopamine -Releasing Protein (Darp)
… of DARP-36aa on the survival of mesencephalic neurons in vitro. Treatment of mesencephalic cultures with DARP36aa resulted in a significant increase in neuron survival and morphological development. Mesencephalic cultures were also incubated with antibodies against DARP-36aa (antiDARP-36aa) in …
-
Influence of Sex, Adolescence, and Aging on the Rat Basolateral Amygdala
… in spine density across age. In study two, neuron number was quantified with stereological methods in the male and female basolateral amygdala at four different ages across the lifespan. The period between adolescence and adulthood was found to be accompanied by significant neuron loss in …
-
EFFECTS OF SOCIAL DOMINANCE ON THE MORPHOLOGICAL AND FUNCTIONAL ACTIVITY OF THE DIENCEPHALIC POSTERIOR TUBERCULAR DOPAMINERGIC NUCLEUS IN ZEBRAFISH (DANIO RERIO)
… Neurogenesis contributed to the increase in PTN neuron number in dominants. Subordinate and isolated fish exhibited signs of oxidative stress. We observed status-dependent shifts in neurotransmitter identity. Dominants displayed elevated PTN activity compared to subordinates. These findings …
-
Conditional Loss of Engrailed 1/2 in Rhombic Lip-Derived Neurons Increases Intrinsic Rhythmicity and Decreases Overall Variability of Eupneic Respiration
… gene Engrailed 1/2 in rhombic lip-lineage neurons and exhibit a proportional scaling-down of neuron number in hypoplastic lobules of the CRB. We utilized whole-body unrestrained plethysmography to measure respiration during eupnea, and evaluated the respiratory sequence of mutant animals …
-
Development of the Mesencephalic Trigeminal Nucleus in the Zebrafish
… as the mammalian MTN. To investigate whether MTN neurons are neural crest-derived, the neural crest was ablated, which resulted in an increase in MTN number. This suggests that the neural crest may play an inhibitory role in MTN development contradictory to previous studies in chick that suggested …
-
Anatomical and physiological properties of the superior paraolivary nucleus in the rat
… paraolivary nucleus (SPON) is a group of neurons located within the superior olivary complex, a constellation of brainstem nuclei involved in auditory processing. The major inputs to the SPON arise from the contralateral ear and SPON axons target primarily the ipsilateral inferior …
-
H5N1 Influenza Virus Induces a Parkinsonian Pathology
… tyrosine hydroxylase positive dopaminergic neuron number and striatal dopamine and its metabolites contents through 90 days post infection (dpi), 2) examined the inflammatory effect of infection by quantitatively measuring the total number of resting and activated microglia in the SNpc and …
-
Smooth Muscle-Specific Removal of Brain-Derived Neurotrophic Factor Results in Increased Vagal Afferent Innervation to the Intestine and Increased Satiation in Mice
… into the nodose ganglion. Nodose ganglion neurons were also quantified to investigate the contribution of vagal sensory neurons to IGLE density. Meal pattern and microstructure analyses were used to determine if any underlying changes in the mechanisms that regulate feeding were associated …
-
Combined bottom-hole pressure calculation procedure using multiphase correlations and artificial neural network models, A
… angle and as well as gas and liquid velocity numbers as input variables. Four possible different flow patterns were considered for upward and horizontal multiphase flow, including bubble flow, slug flow, annular mist flow and stratified flow. Some 3-D plots of all the possible flow patterns at …
-
Effects of bisphenol A exposure during early development on behavior and anatomy of the prefrontal cortex in adult male and female rats
… from these rats to stereologically assess neuron and glia number in the medial prefrontal cortex. Results indicated that levels of T4 at weaning age were significantly altered by exposure to BPA. Additionally, there were also minor indications for learning impairments in the radial arm maze …
-
CNS Neural/Glial Progenitors as Targets of HIV-1 and Opiates: Effects on Proliferation and Population Dynamics May Alter Behavior Outcomes.
… immunoreactivity in these mice was not due to neuron cell death or loss, because the total neuron number in striatum and total striatal volume were not affected by long-term Tat induction. Tat exposure appears to selectively reduce levels of NeuN in living neurons, although the reason is not …
-
Neuroimmune origins of behavioral disorders
… We found that maternal infection reduced neuron number and caused astrocyte-specific gliosis in conjunction with increased expression of select inflammatory genes, three days before anticipated parturition (five weeks-post-inoculation). Additionally, MIA resulted in a reduction in overall …