Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1140 for “"neuron"”.
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Glia-neuron signaling
… from DRG glia;Bradykinin was applied to mixed neuron-glial cultures derived from rat cerebral cortex while monitoring calcium levels. Bradykinin elevated calcium levels in neurons only when neurons contacted glia. The general glutamate receptor antagonist, D-glutamylglycine (DGG), prevented …
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Online neuron reconstruction
… this thesis, I designed an algorithm that traces neurons through the images of various datasets extracted from mouse brains. The algorithm is implemented in Python and relies on the output of a recently developed Fully Convolutional Neural Network (implemented in C) that runs on the underlying …
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A neuron within a neuron: the effect of narrow axonal ER tubules on molecular movement
… and ubiquity of the ER network throughout neurons has earned it the term ‘a neuron within a neuron’. The reasons for its striking continuity are not fully understood, but it could potentially make the ER a channel for long-distance signalling, independent of action potentials at the plasma …
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Neuron-glial interactions in dendrite growth
Interactions between neurons and glia occupy a central role in many aspects of development, maintenance, and function of the central nervous system (CNS). A fundamental event in CNS development is the elaboration of two distinct neuronal processes, axons and dendrites. The overall aim of this …
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Generative probabilistic models of neuron morphology
… it is now possible to image large populations of neurons at single-cell resolution. This imaging capability promises to create a new field of neural circuit microanatomy. Three goals of such a field would be to trace multi-cell neural networks, to classify neurons into morphological cell types, …
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Electronic simulation of an associative neuron
In this thesis the various characteristics of a neuron are discussed at some length. Particular attention is given to the more important features which determine the input and output characteristics and the responses of a neuron. Included are both of the major inhibition characteristics: …
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Genetic Analysis of Variation in Neuron Number
<p>There are large differences in neuron number both within and between species. This variation in neuron number results from both non-genetic and genetic factors. Non-genetic factors, such as litter size and parity, and genetic cofactors, such as sex, age, and body weight, can influence neuron …
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Analysis and reduction of a modeled bursting neuron
A modeled bursting neuron was analyzed using methods based upon geometric singular perturbation theory. The mathematical mechanism of bursting in the model consisted of two slow variables traversing the state-space across a saddle-node bifurcation that defined an interface between quiescence and …
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Profiling the inherent vulnerability of motor neuron subtypes
Motorneuronkrankheiten sind eine heterogene Gruppe von Störungen die in einer selektiven Degeneration der oberen und unteren Motorneurone (MN) resultieren. Die genauen Ursachen für Motorneuronkrankheiten sind kaum verstanden und Behandlungen der Krankheiten begrenzen sich zurzeit auf eine Milderung …
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Artificial Frequency Match Neuron Implemented with Digital Logic
<p>This thesis proposes a digital artificial neuron which uses only digital logic. The purpose is to create a hardware neuron on a digital device. While conventional neurons use real valued software implemented transfer functions and threshold values to determine the output, the proposed neuron …
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Transcriptional control of somatosensory neuron diversification in Drosophila
Primary sensory neurons deliver information from the periphery to specific circuits in the central nervous system. It is vital that each sensory neuron detects the appropriate type of stimulus and conveys that information to appropriate regions of the sensory neuropil to target second-order …
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A Biologically Plausible Neuron Model of Mental Rotation
… The model is comprised of 43,000 simulated neurons spread across a variety of neuron ensembles. These ensembles work together to form a neuronal representation of the spatial map entailed by the stimuli, then rotates that spatial map into a series of new orientations according to simulated …
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Automatic 3D Neuron Tracing from Optical Microscopy Images.
Neuron tracing is the process of reconstructing three-dimensional morphology of neurons from microscopy images. It is essential for delivering more comprehensive understanding of the relationship between neuronal structure and function, which is the fundamental to know how the brain works. However, …
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Utilizing Toxoplasma gondii To Understand Neuron-Specific Neuroinflammation
… persist for the life of the host by hiding in neurons in the Central Nervous System (CNS). It was thought that neurons permitted this chronic infection due to a lack of innate immune capabilities including decreased expression of cytokine and immune cell receptors, as well as an inability to …
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A recovery-renewal model for auditory neuron firings
Thesis: M.S., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 1987
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A microfluidic platform for three-dimensional neuron culture
… typically affect a limited number of specific neuronal subtypes, and the death of these neurons causes permanent loss of a specific motor function. Efforts to restore function would require regenerating the affected cells, but progress is limited by a narrow understanding of the mechanisms that …
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Cortical Pyramidal Neuron Subtype Classification and Visual Response Diversity
… and computation. The classification of pyramidal neurons into functional subtypes remains a crucial part of this survey since the subtype-specific division of labor creates a rich substrate for computation. However, the extreme integration of individual neurons into the collective cortex suggests …
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The role of estradiol in astrocyte and neuron communication
… between the presynaptic, postsynaptic neuron and the neighboring astrocyte. An important characteristic of this astrocyte-neuron communication is the astrocyte responsiveness to neurotransmitters and the subsequent intracellular calcium mobilization. This intracellular calcium signal …
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Morphological characterization of medium spiny neuron development in vitro
Medium Spiny Neurons (MSNs) are the primary cell type of the striatum, a structure critically involved in motivation, memory, and movement. MSN structure and function are altered in Parkinson’s and Huntington’s disease as well as following repeated exposure to drugs of abuse. One site on the MSN …
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Towards the neurocomputer: an investigation of VHDL neuron models
The investigation of neuron structures is an incredibly difficult and complex task that yields relatively low rewards in terms of information from biological forms (either animals or tissue). The structures and connectivity of even the simplest invertebrates are almost impossible to establish with …
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