Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"neuromesodermal"”.
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Assessing the transition state model for cellular differentiation in vivo: a case study of zebrafish neuromesodermal progenitors
… in vivo. In my thesis, I chose to study the neuromesodermal progenitors (NMps) in the zebrafish tailbud due to their relative biological simplicity. These progenitors co-express sox2 (neural marker) and tbxta (mesodermal marker) and differentiate into the posterior spinal cord or paraxial …
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Regulation of polycomb repressive complexes at the neural differentiation gene Pax6
… of the stem zone/caudal lateral epiblast, termed neuromesodermal progenitors. Neural differentiation gene transcription begins in a sharply defined position due to loss of fibroblast growth factor (FGF) signalling. This highly coordinated onset of gene expression implies the involvement of a …
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How to build a chordate: Multiscale decomposition of axial morphogenesis in the amphioxus, Branchiostoma lanceolatum
… I locate a population of vertebrate-like neuromesodermal progenitors that generate the posterior spinal cord. The results I present in this thesis reveal remarkable complexity in amphioxus axial development, and a developmental programme replete with morphogenetic principles shared with …
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The regulation of tissue proportions: analysis of progenitor behavioural dynamics in response to cell ablation in the zebrafish tailbud.
In order to form a correctly patterned embryo the behaviour of cell populations and tissues must be coordinated so that different structures form with the correct relative proportions. The fundamental body plan of the vertebrate embryo is laid down in a head to tail progression known as primary …