Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"neurologic diseases"”.
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Speech-Based Artificial Intelligence Emotion Biomarkers in Frontotemporal Dementia
… spectrum of progressive neurodegenerative diseases that can affect speech production and comprehension as well as higher-order cognition, behavior, and motor control. While profound apathy and deficits in emotion processing are also common symptoms, emotional content has yet to be explored …
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Kh Domains on Brain Polyribosomes: FMRP and Nova in Translational Regulation
… in neurons and is thought to contribute to neurologic diseases such as Fragile X mental retardation syndrome. We demonstrate that several neuronal RNA-binding proteins implicated in human disease are associated with brain polyribosomes, namely the Nova and Hu paraneoplastic antigens and the …
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Fluorescence correlation spectroscopy: ultrasensitive detection in clear and turbid media
… of Alzheimer’s and other neurodegenerative diseases in clinical medicine. A prototype instrument has been built and allowed the detection and quantification of particles down to a few per milliliter in short scanning times. It consists of a small microscope that has a horizontal geometry and …
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Glia-mediated mechanisms of HIV-1-gp120-induced Synaptic Degeneration
… infection of the nervous system causes various neurologic diseases. Synaptic degeneration is a critical underlying neurological pathology. However, the mechanism by which HIV-1 causes synaptic degeneration is unclear. In this dissertation, we tested the role of HIV- envelope protein gp120 in …
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RNA Dynamics in T Cell Activation
… of RNA regulatory processes result in neurologic diseases, cancer, and immunologic disorders among other complications. Posttranscriptional control of RNA is particularly important for precise cytokine expression in T cells during adaptive immune responses. We have studied human …
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The Hu Syndrome: At the Intersection of Cancer and Autoimmunity
<p>Paraneoplastic neurologic diseases (PNDs) arise when systemic malignancies express proteins normally restricted to neurons. Abnormal expression of a neuronal protein by tumor cells in the periphery results in an autoimmune response that then targets both the tumor and the nervous system. These …
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Usutu Virus: An Emerging Arbovirus Threat
… rashes; however, more severe cases can result in neurologic diseases, such as encephalitis and/or meningoencephalitis. In addition to these pathologic similarities, USUV shares several ecological and geographical traits with WNV, a pathogen responsible for several outbreaks during its spread from …
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Improving the Knowledge of EPM
Equine protozoal Myeloencephalitis (EPM) is a neurologic disease in horses predominantly caused by the protozoa Sarcocystis neurona. Carried by the North American opossum, Didelphis virginiana, horses are exposed to S. neurona when eating or drinking food or water contaminated with opossum feces. …
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Can levamisole upregulate the equine cell mediated immune response in vitro?
… is arguably the most common and costly equine neurologic diseases nationwide. The national seroprevalence is >50%, but only 0.5-1% of all horses develops disease during their lifetimes. Some EPM affected horses have decreased immune response. A cell-mediated immune response has been shown to be …