Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"neurogenin1"”.
-
Comparison of transplantation modality of human mesenchymal stem cells expressing neurogenin1 in rat middle cerebral artery occlusion model: intra-arterial vs. intra-cerebral
… study, intra-cerebral transplantation of neurogenin1-expressing MSCs (MSCs/Ngn1) in the animal stroke model dramatically improved neurologic deficits compared with the parental MSCs. However, intra-cerebral transplantation is an invasive method and inappropriate modality for human stroke …
-
New Therapeutic Strategies for Amyotrophic Lateral Sclerosis Treatment
… neural induction of MSCs by overexpressing Neurogenin1, a proneural transcription factor. Depending on transplantation time, systemic transplantation of Ngn1-expressing MSCs (MSCs-Ngn1) delayed the onset of neurobehavioral degeneration or dramatically improved motor functions compared to …
-
Characterization of Neural Stem Cells Using the Nestin Enhancer
Nestin, one of the class VI intermediate filament, is known as a specific marker for neural stem cells and regulated by the enhancer located on the second intron of the gene. The second intron is highly conserved among species and crucial for the nestin expression in central nerve system (CNS) …
-
Role of Sonic Hedgehog in Development of the Central Nervous System
Sonic hedgehog (Shh) functions as a morphogen to induce early dorso-ventral patterning of the central nervous system (CNS) and specifies cell fates of spinal motor neurons. Shh has also been known to promote cell cycle progression of embryonic stem cells as well as adult neural stem/progenitor …