Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 202 for “"neurodevelopment"”.
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Transdiagnostic Approaches to Neurodevelopment
Neurodevelopmental difficulties can have a substantial impact on children’s lives and often have lasting effects in adult life. The scientific study of the causes and consequences of neurodevelopmental difficulties has arguably been slowed by the overreliance on case-control designs, which fail to …
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Early life exposure to metals and adolescent neurodevelopment
… These metals are associated with adverse neurodevelopmental outcomes, with evidence of non-linear associations for essential metals. Metals target brain regions involved in cognition and motor function. However, there is a paucity of epidemiological studies focused on early-life exposure …
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The effect of the cyanobacterial toxin saxitoxin on neurodevelopment
… the role of cellular electrical activity in neurodevelopment this latter pattern of exposure may be of significant public health concern. This background has been addressed in chapter 1; “Low dose extended exposure to saxitoxin and its potential neurodevelopmental effects: a review”, and the …
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The role of AUTS2 in neurodevelopment and neurological disease
… implicated in a wide variety of neurological and neurodevelopmental disorders, including autism, epilepsy, cognitive impairment, and Attention Deficit Hyperactive Disorder (ADHD). Additionally, single nucleotide polymorphisms (SNPs) in the AUTS2 locus are associated with psychiatric disorders, …
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Effects of iron deficiency upon neurodevelopment, metabolism, and inflammation
… first few years of life are a critical period in neurodevelopment. During this time, multiple developmental processes occur in tandem, rendering the brain especially vulnerable to environmental insults. The coordination of complex neuronal processes, including myelination and synaptogenesis, may …
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Neonatal Toxic Stress and Long-Term Neurodevelopment in Premature Infants
… stressors that increase their risk for adverse neurodevelopmental outcomes.</p> <p><strong>Purpose: </strong>The purpose of this study is to examine the relationship among socio-demographic factors, exposure to stressors in the NICU environment, stress modifiers/buffers, neonatal morbidities at …
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ELUCIDATING THE ROLE OF BCAT1 IN MITOCHONDRIAL FUNCTION AND NEURODEVELOPMENT
Branched-chain amino acids (BCAAs) are important nitrogen donors involved in various biochemical processes in the brain and comprise three essential amino acids: Leucine, Isoleucine, and Valine. Regulation of BCAA metabolism influences the central nervous system through multiple mechanisms, …
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Characterising the role of GPR50 in neurodevelopment and lipid metabolism
… previous work indicating a role of GPR50 in neurodevelopment. It also highlights a potential mechanism by which GPR50 regulates neuronal morphology, i.e. via actin remodelling. Reports that GPR50 is involved in energy homeostasis is also supported in this thesis, further, results presented …
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Converging roles of neurodevelopment and Wnt signaling in neuropsychiatric disorders
… autism spectrum disorder, contribution of neurodevelopmental dysregulations to disease etiology in late-onset disorder such as schizophrenia are becoming widely accepted. Therefore, a better understanding of cortical development and functions of Wnt signaling could prove critical in …
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Prenatal Cardiovascular Physiology and Early Neurodevelopment in Cyanotic Congenital Heart Disease
… with congenital heart disease (CHD); however, neurodevelopmental delays and disorders (NDD) are common comorbidities. Studies have demonstrated delays in brain growth and maturation begin as early as the third trimester, with correlations to early neurodevelopmental outcomes. These disturbances …
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THE ROLE OF NADPH OXIDASE IN NEURITE OUTGROWTH AND ZEBRAFISH NEURODEVELOPMENT
… growth cone that guides axonal growth during neurodevelopment and regeneration. Others have reported that inhibition of NOX enzymes during development causes a decrease in the size of some brain areas, and NOX deficiencies in humans are correlated with diminished cognitive function. Despite …
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Curating and summarising data from animal research on neurodevelopment at scale
Neurodevelopmental conditions (NDCs) are a heterogeneous group of lifelong disabilities affecting brain development. While many NDCs arise from a complex combination of genetic and environmental factors, some NDCs are monogenic; animals with targeted alterations in homologous genes can be used as …
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NEUROPROFILES: NEUROdevelopment in PReschool children Of FIfe and Lothian Epilepsy Study
Neurobehavioural problems (i.e. cognitive impairment/behaviour problems) are common in childhood epilepsy. There are very limited data in children with early-onset epilepsy (CWEOE; onset ≤4 years). This study: (1) estimated the incidence of early-onset epilepsy, (2) described the spectrum and …
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Early-life supplementation of osteopontin supports neurodevelopment and influences exploratory behavior
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-09-01 without embargo terms
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Examining the placenta’s role in neurodevelopment in the context of maternal obesity
… of long-term offspring health, in particular neurodevelopment. Various maternal exposures, such as psychosocial stress, diabetes, infection, and high body mass index (BMI) are associated with higher risks of impaired neurodevelopment in the offspring. One third of women in the United States …
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Isoform-Specific Variant and Expression Analysis of Epigenetic Genes in Neurodevelopment and Disease
… Analysis of Epigenetic Machinery Genes in Neurodevelopment and Disease Úlfur Benedikt Fjölnisson¹, Katrín Möller¹, Hans Tómas Björnsson¹,²,³ ¹ Department of Medicine, University of Iceland, Reykjavík, Iceland ² Johns Hopkins University, Baltimore, USA ³ University Hospital, Reykjavík, …
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Infant neurodevelopment and parental psychosocial functioning in pediatric food protein-induced enterocolitis syndrome
… parental psychosocial functioning, and infant neurodevelopment in a sample of infants and toddlers FPIES age 6-18 months and to examine predictors of neurodevelopment. Findings suggested that infants with FPIES are at-risk for problematic feeding concerns with 68.19% reporting clinically …
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Predicting Neurodevelopment in Very Preterm Infants Using Thalamic MRI Features and Machine Learning
… of infant death and is associated with later neurodevelopmental impairments. Neuroimaging is a powerful tool to analyse neuroanatomy abnormalities in preterm infants, allowing the examination of different brain structures, such as the thalamus and its alterations. Notably, the thalamus is a …
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