Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"neurocognitive disorder"”.
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Clinical interventions for HIV-associated neurocognitive disorder (hand) : a systematic review
… use of antiretroviral therapy, HIV-associated neurocognitive disorder (HAND) continues to be one of the most common central nervous system (CNS) complications of human immunodeficiency virus (HIV), with the prevalence of the disorder remaining stable at pre-cART levels. HAND ranges in severity …
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Dementia Subtypes, Cognitive Decline and Survival Among Older Adults Attending a Memory Clinic in Cape Town, South Africa: A Retrospective Study
… Diagnostic and Statistical Manual of Mental Disorders (DSM–5) criteria were used to identify patients with Major Neurocognitive Disorders (dementia). Additional diagnostic criteria were used to determine the specific subtypes of dementia. Linear regression analysis was used to determine crude …
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Hiv And Antiretrovirals In The Central Nervous System: Molecular Mechanisms Of Cognitive Impairment
HIV-associated neurocognitive disorder (HAND) describes a wide range of cognitive impairments experienced by up to 55% of HIV+ individuals despite viral suppression by combined antiretroviral therapy. Reasons for the persistence of this disease are unknown, but may be related to both the presence …
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Applying behavioral management skills training with employees in geriatric care unit to increase social interaction and communication with residents
… may be negatively affected in individuals with a neurocognitive disorder (NCD, i.e., Alzheimer´s Disease). Due to deterioration of executive functions, such as taking initiative, apathy, a lack of motivation, and agitation, there is an increased risk of in-activity for NCD individuals. Due to the …
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Valutazione dei Disturbi Neurocognitivi HIV Associati
… at risk of cognitive impairment (HIV-associated neurocognitive disorders -HAND): also in this context there has been a variation in the presentation spectrum, with a frequency reduction of HIV-Associated Dementia (HAD) and a persistence of the milder forms (ANI, or asymptomatic neurocognitive …
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Robot-Assisted Physical Therapy for cognition and motor skill enhancement in people with dementia.
Dementia is a prevalent neurocognitive disorder that impacts cognition in early stages, resulting in memory loss and gradually affecting mobility and movements in carrying out daily living activities in the elderly population. It poses significant challenges in healthcare, particularly in the …
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Étude des liens entre les mesures quantitatives de la vascularisation cérébrale, les fonctions cognitives et la neuropathologie dans la maladie d’Alzheimer
… people worldwide will be affected by a major neurocognitive disorder (TNC) in 2030. However, the etiology of Alzheimer's disease (AD), the most common form of major TNC, remains unclear. Given the growing body of evidence supporting a relationship between vascular factors and AD, the present …
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MODELING PRO-INFLAMMATORY CROSSTALK BETWEEN MICROGLIA AND ASTROCYTES DURING HIV INFECTION
HIV-Associated neurocognitive disorder (HAND) is a spectrum of cognitive deficits observed in 50% of people living with HIV (PWH). HAND is associated with viral transcription in the central nervous system (CNS) and neuroinflammation, though the mechanisms that drive this pathology remain poorly …
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Unravelling the molecular mechanisms of HIV associated neurocognitive disorders through mass spectrometry-based proteomics
… dysfunction that characterises HIV associated neurocognitive disorders. While the molecular aetiology of this important HIV complication remains largely uncharacterised, HIV transactivator of transcription (HIV-Tat) has been identified as a plausible aetiological cause. Here we have used mass …
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Grey matter morphological changes in late life using magnetic resonance imaging technique
… on hippocampal atrophy. MCI is a heterogeneous neurocognitive disorder that can be classified into various subtypes. However, most of these neuroanatomical studies on GM changes in MCI have focused on the amnestic MCI subtype. The third research topic aims to examine the grey matter (GM) atrophy …
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Effect of High Antioxidant Cacao Consumption on Behaviors in Children with Autism Spectrum Disorder
<p>BACKGROUND- Children with Autism Spectrum Disorder (ASD) demonstrate a physiological imbalance between free radicals, resulting from oxidative stress, and antioxidants. Oxidative stress is linked to the pathogenesis of this neurocognitive disorder. The objectives of this pilot feasibility study: …
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A Transferrin conjugated nanoemulsion system for brain delivery of antiretroviral therapy
HIV- associated neurocognitive disorder (HAND), also known as HIV encephalopathy and AIDS dementia, is one of the critical complications of HIV infection that causes severe morbidity and even shortens survival. This complication is challenging to treat because most of the antiretroviral therapeutic …
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The effect of HIV-1 Tat and methamphetamine on expression of cytokines/chemokines and synaptic genes: Implications in HIV neuroAIDS
… cognitive dysfunctions, including asymptomatic neurocognitive impairment (ANI) and Mild neurocognitive disorder (MND). These neurological deficits affect approximately 50% of HIV-1 infected people. The neurotoxicity of HIV-1 has been attributed to the virus itself or the viral proteins like …
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The Role of Specific Integrase Strand Transfer Inhibitors (INSTIs) in the Alteration of Oligodendrocyte Maturation and Myelination in Hand
… patients clinically manifest with HIV-associated neurocognitive disorder (HAND), a spectrum of cognitive, motor, and behavioral abnormalities which histologically present as non-specific gliosis, synaptodendritc damage and loss of white matter and myelin. Furthermore, the severity of white matter …
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Screening for HIV-associated neurocognitive disorders in perinatally infected youth: Validation of the CAT-rapid version 2 screening tool
… Tool Rapid v2 tool in screening for all forms of neurocognitive impairment in a sample of youth living with HIV in Cape Town, South Africa. Design: We analysed the existing dataset of the neuro sub-study which was nested within the larger CTAAC study (Cape Town Adolescent Antiretroviral Cohort). …
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An Investigation of Male Observation Cases That Had Been Charged With Murder to Compare Those Diagnosed With Schizophrenia to Those Diagnosed With Bipolar or Schizoaffective Disorders
… of schizophrenia or bipolar/schizoaffective disorder and to establish if there are any differences between the two patient groups. Methods Clinical records of male patients diagnosed with schizophrenia or bipolar/schizoaffective disorder following a charge of murder who had been admitted as …
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Caregiver training to enhance care interactions with persons with neurocognitive disorders: An additive treatement study
<p>Persons with neurocognitive disorders (NCD) rely on family and friends to help them with everyday tasks, yet informal caregivers might not be aware of the need to scaffold tasks or know how to maximize the care recipients’ engagement. The current study recruited three men who were full-time …
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An investigation of a neuro-inflammatory profile of HIV-associated neurocognitive disorders
Background HIV-associated neurocognitive disorder (HAND) is the consequence of the effects of HIV-1 within the central nervous system (CNS). HIV-associated neurocognitive impairment differs in severity with milder forms presenting in 50% of people living with HIV (PLWH), regardless of treatment …
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HIV-1 gp120 and Methamphetamine-mediated Induction of Proinflammatory Cytokines/chemokines and Oxidative Stress in Astrocytes: Implications in Neuroinflammation
HIV associated neurocognitive disorder (HAND) remains a major concern for patients infected with HIV. The viral envelope protein, gp120 has been extensively studied and some of its neurotoxic effects are due to the increased expression of various proinflammatory cytokines. Additionally, it has been …
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Using Smartphone Applications to Support Cognition in Individuals with Parkinson’s Disease: A Pilot Treatment Study
Cognitive impairment from Parkinson’s disease can limit performance in daily activities, reduce participation in social/leisure activities, and increase caregiver burden. A 5-week treatment program was developed to train the use of smartphone applications to support cognitive functioning in …
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