Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"neuritogenesis"”.
-
Role of Reelin-Dab1 Signaling in the Neuritogenesis
… depression was rescued by Reelin treatment. The neuritogenesis has been known to be promoted by the activation of Gαi/o signaling. Activated Gαi and Gαo were obviously localized in terminal portions of growing neuritis. Here, I study that a crosstalk between Reelin and Gαi/o signaling is involved …
-
The Nrg Growth Factors and Their Receptor ErbB4 in the Developing Brain: Delineation of Nrg3 Expression and Neuritogenesis
The developing brain is a highly dynamic structure, making it repeatedly vulnerable to possible developmental abnormalities that can endure into adulthood. The neuregulin (Nrg) family of growth factors (Nrg1-4) and their receptor, ErbB4, have been linked to mental illnesses considered to emerge as …
-
The growth-arrest-specific protein gas7 potentiates neuronal differentiation
… nitroprusside. The ability of gas7 to potentiate neuritogenesis and neuronal differentiation makes it a potential therapeutic target to promote re-establishment of neuronal connections in the injured or diseased brain, such as following stroke.
-
Biological Functions of Iduronic Acid in Chondroitin/Dermatan Sulfate in Tumor and Brain Development
… fields. It also comprises the role of CS/DS in neuritogenesis. The present investigation section presents the potential role of DS-epimerase 1 in tumor biology with emphasis on migration of tumor cells. Downregulation of DS-epi1 in a esophageal cancer cell line results in reduced invasion and …
-
Farnesylation-dependent regulation of transcripts by PARP13
… yet another important cellular process such as neuritogenesis.
-
Investigating the Molecular Function of APP Interacting Proteins in Synaptic Neuromodulation
… compared to age-matched controls, and neuritogenesis was promoted in human neuroblastoma cell lines by CNTN4 and APP overexpression in a non-additive manner. Pull-down data indicated that CNTN4 interacts with the GluA1 and GluA2 subunits of AMPARs primarily via its extracellular …
-
Actin dynamics in silico, in waves, and in rods
… to transport actin to growth cones and support neuritogenesis. Using diffusional analysis, we were able to demonstrate that neuronal waves transport actin. Neuronal waves provide a unique mechanism for transporting actin in that the delivery of actin is dependent upon actin itself and its …
-
Role of Membrane Contact Sites in the Neuropathogenesis of GM1-Gangliosidosis
… binding proteins. GM1 is also known to promote neuritogenesis through the activation of phosphorylated TRKs, receptors for neurotrophic factors. Under disease conditions, GM1 accumulates not only in the PM but also in the intracellular membranes of organelles, altering their membrane composition …
-
Evaluation of inhibitors of histone deacetylases as potential neurotrophic agents
<p>The inhibitors of histone deacetylases (HDACs) have shown promising neuroprotective and neuroactive properties. A set of pan- and isoform-specific HDAC inhibitors were evaluated for neurotrophic activity on Neuroscreen-1 (NS-1) cells, a subclone of PC-12 (rat pheochromocytoma) cells. </p> <p>The …