Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"neural probe"”.
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Reconfigurable neural probe for chronic recording
To facilitate the usage of neural prosthesis, a sustainable recording method of cleaner neural signals is desired. While invasive neural electrodes can record neural activities with less noise than non-invasive methods and provide the ideal spatial-temporal resolution of the recorded signal, one …
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Design and development of a fluid actuated neural probe for chronic sensing
Neural implants have found a niche in circumventing brain dysfunction for brain-machine interfaces and in neuroscience studies for interrogation of neural tissue. The performance of implantable neural probes for chronic applications has been hampered, owing to an inflammatory immune response in the …
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Functional thin film polymers for biopassivation of neuroprosthetic implants
… Central to this field is the ability to implant neural recording probes within the brain that will remain functional over the life of the patient. In this work, two novel polymeric materials for use in biopassive neural probe coatings have been developed and validated. These polymers are …
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Opto-fluidic neural probes for optogenetic brain interrogation
… beam shaper that can be integrated into thin neural probe shanks is presented along with its integrated photonics backbone. These beam shapers are experimentally demonstrated to focus light to a variable volume from 2 cubic micron to as small as 0.06 cubic micron, corresponding to NAs as high …
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Nanoporous dialysis membrane for microfluidic neural probes
Understanding the functionality of neural circuits is important for not only research but also the development of novel treatment of neurological disorders. As the communication between cells in the brain is mainly via neurochemicals, the detection of neurochemicals is vital to understand brain …
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Reconfigurable neural probes for chronic electrical recording
… the nervous system are critical for enabling neurally-controlled prostheses and for creating better therapies for neurological disorders. Microelectrodes that penetrate into brain tissue to record extracellular electrical activity are one such neural interface technology known for their …
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A tailored biocompatible neural interface for long term monitoring in neural networks
Neural interface electrodes that can record from neurons in the brain for long periods of time will be of great importance to unravel how the brain accomplishes its functions. However, current electrodes usually cause significant glia reactions and loss of neurons within the adjacent brain …
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3-Dimensional Intracortical Neural Interface For The Study Of Epilepsy
… pattern. </p> <p>This work reports a novel neural probe technology for the manufacturing of 3D arrays of electrodes with integrated microchannels. This new technology is based on a silicon island structure and a simple folding procedure. This method simplifies the assembly or packaging …
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Study of mechanical effects of microfluidic channels in microneedles
Modern neural probes integrate microfluidic chemical sampling to measure spatio-temporal neurochemical transients in the brain while also pursuing miniaturization to minimize tissue damage. This brings into question the effect of the integrated microfluidic channels on the mechanical integrity of …
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A biocompatible, local drug delivery platform for the chronic treatment of neurological disorders of the brain
… nature. The injectrode is a multifunctional probe designed to treat neurological disorders through targeted chemical and electrical stimulation directly to a focal point within the implicated neural circuit. This thesis details the characterization and biocompatibility of the injectrode for …
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Long silicon microfluidic needles for VTA and in-vivo differential neurochemical measurement
… in vivo evaluation of long silicon microfluidic neural probes intended for high-resolution neurochemical sampling from deep brain nuclei such as the ventral tegmental area in mice. The work first analyzes stress-induced bending in thinfilm cantilever structures on silicon-on-insulator substrates …
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A microfluidic silicon nanodialysis platform with in-channel electrochemistry for analyte sampling, timestamping and detection at high spatiotemporal resolution
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-08-01
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Microfabrication and Electrochemical Characterization of a Novel SU-8 Probe with an Array of Individually Addressable Electrodes Suitable for Redox Cycling Experiments in Ultra-small Volumes
… low concentrations or in sensitive tissues. A probe on a polymeric SU-8 substrate with suitable dimensions and robustness for in vivo neural measurements was developed and tested in vitro. The probe’s unique construction using microfabrication processes and a laser-machining procedure is …