Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"neural injury"”.
-
Automated multi-well neural injury device
Traumatic Brain Injury (TBI) is a wide spread pathological problem occurring in 1.4 million individuals every year according to the National Institute of Neurological Disorders and Stroke. There are several types of TBI and the most prominent ones are concussion, contusion, hematoma, …
-
Neural injury following traumatic anterior shoulder dislocation
In this study I reviewed 28 patients with brachial plexus lesions caused by shoulder dislocation. As far as can be established, this is the largest series reviewed in the literature to date. Contrary to most other reports, the neurological lesions involved the supraclavicular as well as the …
-
EXERCISE IS NEUROPROTECTIVE TO MOTONEURON DENDRITES FOLLOWING PARTIAL MOTONEURON DEPLETION VIA A MECHANISM DEPENDENT ON ANDROGEN RECEPTORS AT THE TARGET MUSCLE
… is not able to confer resilience to subsequent neural injury, but that exercise may confer androgen sensitivity to a previously insensitive neuromuscular system. The findings in this dissertation demonstrate that exercise is neuroprotective to motoneurons via the same mechanism of androgen …
-
E2F6 in axial skeletal development and gliosis
… and self-renewal properties of hematopoietic and neural stem cells. However, E2F6 does not participate in the repression of the Ink4a-Arflocus. These findings underscore the significance of the E2F6-Bmil interaction in vivo and suggest that the Hox and Ink4a-Arfloci are regulated by somewhat …
-
Zinc ion homeostasis in cellular physiology and experimental models of traumatic brain injury
… yet unsolved quest in treating traumatic brain injury (TBI) is the understanding of the secondary cellular injury that contributes to cell death. Whether zinc ions are toxic or protective in TBI is controversial. As an essential human micronutrient, zinc is needed for the structure and function …
-
Plasticity of neurons in mouse major pelvic ganglia in response to loos of physiological input in cases of nerve injury and spinal cord injury
… patients. Most people with spinal cord injury (SCI) reported a desire to recover autonomic functions such as bladder and sexual functions over regaining of locomotor functions. Lower urinary tract function is one of the autonomic functions that is impaired after SCI. Acute SCI results in …
-
Modelling of the Human Corticospinal Motor Axis and Its Injury Using Organoids
Spinal cord injury (SCI) is a debilitating disease which lacks viable treatment options. Thus, affected individuals may find themselves both functionally and socioeconomically disadvantaged with limited therapeutic avenues to explore. While there has been great progress in understanding the …
-
Astrocytic Sonic Hedgehog signalling in development and disease
… neonatal stroke (Nguyen et al., 2021), hypoxic injury (Heine et al., 2011), and neurodegenerative disease (Li et al., 2020). In these settings, Shh signalling has been shown to mitigate neuronal damage, enhance cell survival, and support tissue repair, highlighting its potential as a therapeutic …
-
Behavioral Insights Into Nociceptor Function: A Systematic Approach to Understanding Postsurgical and Neuropathic Pain Mechanisms In Rats
… noxious probes. Rats with a thoracic spinal cord injury (SCI), lumbar spinal nerve transection, or chronic constriction injury of the sciatic nerve, as well as their sham controls, exhibited heightened pain-avoidance behavior compared to uninjured controls. These findings have important …