Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"network meta-analysis"”.
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An Applied Bayesian Approach to Network Meta-Analysis
<p>Network meta-analysis has been introduced as an extension of pairwise meta-analysis to facilitate indirect comparisons of multiple interventions that have not been studied in a head-to-head fashion. The use of network meta-analysis is becoming increasingly popular in biomedical sciences, …
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NETWORK META-ANALYSIS OF ORAL AND MAXILLOFACIAL REGENERATION PROCEDURES
… maxillofacial regeneration. Since traditional meta-analysis compares only two types of intervention, network meta-analysis has been used as most common method to compare multiple interventions from different clinical trials. Therefore, using this methodology our main aim was to determine the …
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Network meta-analysis with rare events and misclassified response.
… sensitivity analyses into part of the total data analysis. In this dissertation, we extend previous work on Poisson regression models that allow for misclassification by thoroughly discussing the basis for the models and allowing for extra-Poisson variability in the form of random effects. Markov …
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Statistical methodologies for network meta-analysis with applications in veterinary medicine
Network meta-analysis (NMA) has become a popular method with which to conduct research syntheses pertaining to multiple interventions, as it allows for the comparison of interventions that have not been directly compared and typically improves precision of the comparative effect estimates relative …
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Toward valid network meta-analysis: Challenges in clustering conservative interventions for musculoskeletal conditions
A network meta-analysis (NMA) is a statistical technique that combines and compares multiple interventions from direct and indirect evidence in one analysis, ranks them according to their effectiveness, and assists clinicians in making better-informed decisions within an EBP framework. Conducting …
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A Systematic Review and Network Meta-Analysis of Psychosocial Interventions for Adults who were Sexually Abused as Children
… of a systematic review, series of pairwise meta-analyses, moderator analyses, and network meta-analyses, investigates the comparative effectiveness of various treatments for adults who experienced sexual abuse as children.</p> <p>Over 17,000 studies were screened for pre-determined …
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Comparative effectiveness of non-pharmacological interventions for preventing cognitive decline in older adults: a systematic review and network meta-analysis
… This study conducted a systematic review and network meta-analysis of randomized controlled trials evaluating lifestyle interventions in older adults at risk of dementia. Searches of PubMed, PubMed Central, Clinicaltrials.gov, and Cochrane Library (collection to February 2026) identified 18 …
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Enhancing the Use of Network Meta-analysis to Synthesize Information on Benefits and Harms of Drugs to Support Regulatory and Reimbursement Decisions in Canada
BACKGROUND AND OBJECTIVES: Standard meta-analysis compares two treatments whereas network meta-analysis compares multiple treatments. In light of the increasing number of treatments available, we have seen a shift from using standard meta-analysis towards using network meta-analyses to support …
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Bayesian approaches for survival data in pharmaceutical research.
… of which are motivated by real-world problems in network meta-analysis, prior elicitation, and adaptive designs. Network meta-analysis is a hierarchical model used to combine the results of multiple studies, and allows for us to make direct and indirect comparisons between treatments. We …
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Informed Decision Making for Patients with Advanced Pancreatic Cancer Considering Chemotherapy: Development and Evaluation of a Clinical Decision Aid for Patients
… Therefore, a systematic review and Bayesian network meta-analysis of randomized clinical trials was conducted using gemcitabine, the standard treatment, as the reference comparator. Based on results from the network meta-analysis, in which optimal treatments were identified and side effects …
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Cardiovascular Disease: Prevention and Management
… muscle symptoms (SAMS) in large RCTs utilizing a network meta-analysis. The second, using a large administrative insurance claims database, will estimate whether the risk of VTE in post-menopausal women on hormone therapy is reduced with statin exposure. The third project is a community …
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Estimation of education quality: harmonization and analysis of inequalities
… a single assessment scale using a newly applied network meta-analysis strategy. Inequalities in harmonized estimates of educational quality were identified across region, country, and socioeconomic status (SES) using absolute and relative measures of inequality. Results: There are significant …
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Statistical methods for multivariate meta-analysis
… of the drawbacks of using separate univariate meta-analyses to solve a clearly multivariate problem. This has led to increased attention to multivariate meta-analysis, which is a generalization of standard univariate meta-analysis to synthesize evidence on multiple outcomes or treatments. …
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Bayesian methods to estimate the accuracy of diagnostic tests in meta-analysis models.
… diagnostic tests, combining the studies into a meta-analysis becomes an important and increasingly viable area of statistics, especially within the medical field. We begin by developing a hierarchical Bayesian prior structure to estimate prevalences and misclassi cation rates for a single …
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Optimising service organisation for stroke patients
… using various basic frequentist and Bayesian meta-analysis techniques as well as more complex meta-analysis ideas. These more complex ideas include: meta-regression where covariate information is incorporated into the model; and network meta-analysis where direct and indirect information is …
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Innovative Multivariate Meta-Analyses Methods For Diagnostic Tests And Multiple Treatments
Systematic reviews and meta-analyses are critical tools for synthesizing evidence from multiple studies and supporting healthcare decision-making on diagnostic tests and multiple treatments. Assessing a diagnostic test often lacks a gold standard, i.e., a perfect reference test. Without a gold …
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Design, development, and evaluation of a web-based information tool to support decisions on treatment options for people with advanced pancreatic cancer: A mixed-methods study.
… medical evidence through systematic review and network meta- analysis of randomised controlled trials, (3) design and (4) evaluation of a WIT through a human-centred design (HCD) approach. Participants were adult patients diagnosed with APC and their relatives, clinical nurse specialists, …
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Techniques for comparing efficacy and cost-effectiveness of cancer therapies, and improved inference tools
… interventions in patients with advanced or metastatic melanoma within a Bayesian setting. Currently, chemotherapy is established as the standard of care for melanoma, but is often associated with poor responses and short survival. However, recent groundbreaking discoveries in tumor biology …
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Overcoming Avoidable Research Waste in Carious Lesion Management Research
… to appropriately update these reviews. An analysis of updated systematic reviews is presented which shows that several problems arise from the primary literature on which they are based. Inconsistent outcome selection and reporting is one of those problems. Solutions to the issue of …