Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 2243 for “"nervous system"”.
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UCHLI in the Mammalian Nervous System
UCHL1, or Ubiquitin Carboxy Terminal Hydrolase L1, is a de-ubiquitinating enzyme (DUB) thought to be involved in ubiquitin recycling. Beyond this, its natural function is almost wholly unknown. Mice lacking this enzyme exhibit a severe and rapidly progressing neurodegenerative phenotype. Using one …
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Genetic Analysis of Drosophila Stomatogastric Nervous System
The enteric nervous system (ENS) is of critical importance to an organism, as it controls the function of the gastrointestinal system. The ENS is remarkably complex, and although sculpted early in development, has to maintain plasticity throughout adulthood in the face of changing food levels, …
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Cell biomechanics of the central nervous system
… In order to understand how cells of the central nervous system (CNS) respond to mechanical insults and stimuli, a combined modeling/experimental approach was adopted. A computational framework was developed to accurately model how cells deform under various macroscopically imposed loading …
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Effects of sleep deprivation on autonomic nervous system
… events by increasing the sympathetic nervous system activity. The aim of the present study was to evaluate the relationship between sleep deprivation and the autonomic nervous system activity by means of heart rate variability (HRV) and blood pressure variability (BPV). All data were …
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Allocation of Computational Resources in the Nervous System.
The nervous system integrates past information together with predictions about the future in order to produce rewarding actions for the organism. This dissertation focuses on the resources underlying these computations, and the task-dependent allocation of these resources. We present evidence that …
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Axon-glia interactions during central nervous system myelination
Myelination drastically speeds up action potential propagation along axons, which is fundamental for the correct function of neuronal circuits. However, axon-oligodendrocyte interactions regulating the onset of myelin formation remain unclear. I sought to determine how reticulospinal axons control …
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Regeneration and maintenance of the planarian nervous system
… regenerate all tissues, including the central nervous system and the eyes. This process depends on a population of cells in the adult, the neoblasts, that includes pluripotent stem cells. Whether the neoblast population also includes progenitors specialized for forming specific lineages has not …
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Multivariate Discrimination of Emotion-Specific Autonomic Nervous System Activity
The present study investigated autonomic nervous system (ANS) patterning during experimentally manipulated emotion. Film clips previously shown to induce amusement, anger, contentment, disgust, fear, and sadness, in addition to a neutral control, were presented to 34 college-aged subjects while …
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Neuronal plasticity in the enteric nervous system motor pathways
… underlying neurotransmission within the enteric nervous system are not yet known. Acetylcholine acting on nicotinic receptors mediates the majority of fast synaptic transmission between enteric neurons, however, recent studies suggest that the peristaltic motor pattern can occur during nicotinic …
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Alginate-based Hydrogels for Central Nervous System Tissue Regeneration
As the central nervous system shows very little capability for self-repair following injury, regenerative medicine approaches are increasingly interested in the use of stem cells for cell replacement strategies. Biomaterials are an interesting tool to carry out this type of therapies. They allow …
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Spontaneity and Precision in the Drosophila Central Nervous System
… might provide insight into how a heading system can store an angular memory in complete darkness, without significant drift, for many minutes.</p>
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GENETIC CONTROL OF EYE AND CENTRAL NERVOUS SYSTEM DEVELOPMENT
Aniridia, a congenital ocular disorder caused by haploinsufficiency of transcription factor PAX6, is characterized by complete or partial iris hypoplasia with associated foveal hypoplasia. Brain imaging performed in patients heterozygous for PAX6 mutations often reveal absence of the brain anterior …
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Functional Characterization of Neurexophilins in the Central Nervous system
In der vorliegenden Arbeit wurde die Lokalisation und Funktion von Neurexophilinen mittels eines neurogenetischen Ansatzes im Gehirn von Mäusen untersucht. Neurexophiline (Nphs) konstituieren eine Proteinfamilie von Glykoproteinen, die ursprünglich als eine Komponente der alpha-Neurexine isoliert …
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On the chemical dynamics of the central nervous system
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
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Profiling and Imaging the Nervous System With Mass Spectrometry
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2008.
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Transcriptional profiling of Drosophila larval ventral nervous system hemilineages
… and morphologically similar neurons makes this system tractable to RNA-seq analysis, since one can genetically label and isolate many cells per animal, which are predicted to share similar gene expression profiles. Our primary focus is to examine hemilineages with similar targets (e.g. leg …
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Promoting Central Nervous System Regeneration by Targeting Intracellular Pathways
Adult central nervous system neurons regenerate poorly after injury. One reason for this regenerative failure is that a developmental change occurs where essential growth-molecules become excluded from axons with maturation. In this thesis, two strategies were employed in order to improve axon …
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Expression and function of proteoglycans in the nervous system
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1995.
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