Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 45 for “"nerve tissue"”.
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Nerve tissue engineering using blends of Polyhydroxyalkanoates
… of biomedical applications, particularly in tissue engineering and drug delivery. The properties of PHA devices can be successfully modified through the fabrication of composites and blends. Such modifications allow for further tailoring of properties such as biocompatibility, mechanical …
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Development of antibacterial Polyhydroxyalkanoates for their use in nerve tissue engineering
The fabrication of nerve conduits (NGCs) with the appropriate features for a successful nerve regeneration is not always possible/fulfilled. The currently available implants partially meet the requirements of such medical devices. Despite the evolution of the polymer field and hydrogels, not much …
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Proteomic comparison of biomaterial implants for regeneration of peripheral nerve tissue
Tissue regenerates resulting from the healing of transected peripheral nerve differ in morphological and electrophysiological properties based on the biomaterial implant used to bridge the interneural wound gap. At gap lengths >/=10 mm, impermeable silicone tubes promote little to no nerve …
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Deposition of Electroactive Polymers onto Polymer Nanofibers for Nerve Regeneration
Although peripheral nerves can regenerate after an injury through the Wallerian degeneration process, the degree of regeneration is often not efficient enough to achieve full return of functionality. To overcome the disadvantages of current nerve repair approaches, peripheral nerve tissue …
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Mechanical modeling of tissue response during early stage entubulated peripheral nerve regeneration
After severe peripheral nerve injury, such as transection, regeneration has been observed over variable gap lengths with the use of the nerve stump entubulation method. Following entubulation, exudate from transected nerve stumps coagulates into a fibrin matrix within the entubulated space by the …
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Development of a head-mount fiber scanning system for imaging in vivo
… necessary for acquiring functional data from nerve tissue by application of two-photon laser scanning microscopy and its miniaturization for in vivo imaging in freely moving animals. The construction of a laser with enhanced repetition rate and the design of a novel non-resonant fiber scanning …
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In vivo studies of suspected mechanisms of DDT-resistance in Blattella germanica (L.)
… a reduced binding capacity of resistant insect nerve tissue for the DDT molecule as compared to susceptible insect nerve tissue.
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Visualization of neuronal geometry in ventral nerve cord ganglia of Acheta domesticus
… of innervation, or neuronal geometry, of various nerves leading to their respective ganglia (Fig. 1) and to obtain visualization of the finest terminal branches. A description of the cellular arrangement of a segmental ganglion would be of value in better understanding the results obtained when …
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Strategies for optogenetic stimulation of deep tissue peripheral nerves
… an opsin, such that illumination of the target tissue initiates depolarization; in the case of a neuron, illumination results in the firing of an action potential that can control downstream physiology. The excitement surrounding optogenetics has also extended to the clinic with a human trial …
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Initial experience of intraoperative identification of parathyroid glands with elastic scattering spectroscopy
… of the parathyroid gland from surrounding tissues in real-time. METHODS: ESS optical signatures were collected intraoperatively from perfused parathyroid, thyroid, fat, muscle, and nerve tissue during thyroidectomy. The ESS data was collected using a portable, handheld, noninvasive, "cold" …
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The extraction of type 1 collagen and the fabrication of multi-filament embedded hydrogels for guided nerve regeneration
… the greatest challenge. Since the development of nerve conduit to facilitate general axonal regeneration, the primary focus has changed to directing the regeneration of axons while also promoting their outgrowth over very extensive lesions to ensure functional recovery of transected nerves during …
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Neural differentiation of pluripotent stem cells and applications to micropatterned agarose hydrogel for nerve guidance
… stem (ES) cells, an attractive source for nerve tissue repair and regeneration due to their unlimited capacity for self-renewal and their ability to differentiate into all major cell lineages. Bioengineered 3-D hydrogel culture systems have the potential to elucidate mechanisms required for …
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EFFECTS OF AT1R ANTAGONIST L-158,809 ON NORMAL BRAIN TISSUE INJURY FOLLOWING WHOLE-BRAIN IRRADIATION
… caused by injury to irradiated normal brain tissue. The cellular and molecular mechanisms underlying radiation-induced normal brain tissue injury have not been fully elucidated. Neuroinflammation, in the form of microglial activation, and decreased hippocampal neurogenesis frequently occur in …
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Morphology of Acercaria: investigations of the ovipositor and internal anatomy
… describes an effort to investigate digestive and nerve tissue morphology, which has previously been hypothesized to be phylogenetically informative in acercarians (Goodchild 1966; Niven et al 2009). X-ray micro-computed tomography was used instead of conventional dissection for this task, which …
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The effect of aphid lethal paralysis virus (ALPV) on the biology of grain aphids in the Western Cape
… for low levels of virus in infected aphid body tissues where inapparent infection could cause detection problems. ALPV was visualized in ultrathin sections of diseased aphid body tissues by immunocytochemistry utilizing immunogold label. ALPV antigen was detected in the ovariole tissue, …
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Imaging studies of peripheral nerve regeneration induced by porous collagen biomaterials
… to induce regeneration in skin and peripheral nerves, however still there is no complete explanation about the underlying mechanism. This thesis utilizes advanced microscopy to study the expression of contractile cell phenotypes during wound healing, a phenotype believed to affect significantly …
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Technologies of living substance : tissue culture and cellular life in twentieth century biomedicine
… and cultural analysis of the development of tissue culture, that is, techniques for growing living cells and tissues outside of the bodies of complex organisms. The development of these techniques represents an important epistemological shift in biology from in vivo to in vitro …
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Investigation into the dispensing-based fabrication process for tissue scaffolds
Tissue engineering is a multidisciplinary subject aimed at producing the immunologically tolerant ‘artificial’ tissues/organs to repair or replace damaged ones. In this field, tissue scaffold plays a key role to support cell growth and new tissue regeneration. For fabrication of tissue scaffolds …
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Synthetic studies toward 6-deoxy-ß-D-ido-heptopyranosides related to capsular polysaccharides of Campylobacter jejuni
… cross-react with human gangliosides present on nerve tissue, resulting in neurological complications (e.g. acute paralysis) from immune-mediated destruction of the nervous system. The capsular polysaccharide (CPS) of C. jejuni contains a unique repeating disaccharide unit which includes an …
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Electromechanical Effects in Bone and Nerve
Submitted by Carolyn Rauber (crauber2@illinois.edu) on 2011-06-02T16:41:30Z No. of bitstreams: 1 1982_gross.pdf: 7017300 bytes, checksum: 29a11ef25d2ef4cbca3d676400a2cea2 (MD5)
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