Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"nerve excitation"”.
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Effects of Irreversible Electroporation and High-Frequency Irreversible Electroporation for the Treatment of Breast Cancer
… cancer cells without muscle contractions and nerve excitation, and allows for more tunable treatment parameters. Throughout my thesis, I discuss investigations of H-FIRE for the treatment of triple-negative and hormone-sensitive BC cell lines and compare efficacy to IRE outcomes. To further …
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Combinatorial Treatments and Technologies for Safe and Effective Targeting of Malignant Gliomas Using High-Frequency Irreversible Electroporation
… the desired tissue ablation while minimizing nerve excitation and muscle contractions. Additionally, H-FIRE reduces susceptibility to electrical heterogeneities, allowing for more predictable treatment volumes, thus enhancing the feasibility of clinical translation. This dissertation …
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Advancements in the Treatment of Malignant Gliomas and Other Intracranial Disorders With Electroporation-Based Therapies
… constant (~1 μs) to ablate tissue while reducing nerve excitation, muscle contraction, and is far less prone to differences in electrical heterogeneities. Throughout my dissertation, I discuss investigations of H-FIRE for the treatment of malignant gliomas and other intracranial disorders. To …
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A Study of Ionic Permeability Changes Underlying Excitation in Myelinated Nerve Fibers of the Frog
… potential and related phenomena typical of nerve excitation. Constraint of the membrane potential (the voltage clamp) provided direct measurement of the current carried by the movement of ions through the membrane. By applying operational procedures analogous to those used by Hodgkin and …
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Improvements in Pulse Parameter Selection for Electroporation-Based Therapies
… positioned near major vessels, ducts, and nerves. Since its introduction in the late 2000s, IRE has been used successfully to treat thousands of patients with focal, unresectable malignancies of the pancreas, prostate, liver, and kidney. It has also been used to decellularize tissue and is …
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Inhibitory Fields in the Limulus Lateral Eye
… bands) in the response pattern of the optic nerve. A theoretical analysis of the contrast phenomena indicates that the shape of the Mach bands is determined by the configuration of the inhibitory field. Patterns of the optic nerve activity in response to simple, stationary patterns of …