Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"nephrotoxic serum"”.
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A Non-Canonical Function for NLRP3 and AIM2 in Kidney Diseases
… tubules at a low level. In a mouse model of nephrotoxic serum (NTS)-mediated anti-GBM, Aim2-/- mice displayed increased glomerular cellular crescent (multilayered accumulation of activated parietal cells) formation, tubular injury and inflammation, and worse renal function compared to …
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Characterisation of the Effect and Functional Significance of Fcγ Receptor Crosslinking on Metabolic Processes in Macrophages
… following administration of intravenous IC, or nephrotoxic serum, kidney macrophage activation was abrogated by glycolysis inhibition or by myeloid HIF-1a deficiency. Together my data reveal the cellular molecular mechanisms required for FcγR-mediated metabolic reprogramming in macrophages and …
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Factors affecting severity of injury in allergic renal disease
Experimental studies of nephrotoxic nephritis in animals have demonstrated many of the underlying pathogenetic mechanisms involved in human glomerulonephritis. The first part of this thesis reviews the literature with regard to the factors and mechanisms responsible for the causation of …