Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"neonatal infection"”.
-
Development of a novel infection model to test CSF1-Fc as a potential therapeutic for early onset sepsis
… dysregulation of the host immune response to infection, involving stages of hyperinflammation that mediate organ damage and dysfunction. Early onset sepsis (EOS) is defined as onset within the first 72 hours after birth. It is caused by ingestion or inhalation of infected fluids either in …
-
The adherence to group b streptococcus screening guidelines amongst pregnant women in Western Australia – A quantitative descriptive analysis
… B Streptococci (GBS) is a major risk factor for neonatal infection acquired via vertical transmission during pregnancy, labour, or birth, potentially resulting in significant morbidity and mortality. Universal screening at 35 – 37 weeks gestation for maternal GBS colonisation and the use of …
-
Enduring Effects of Early Life Inflammation on Stress-related Microglial, Neuronal and Behavioral phenotypes
… maternal obesity via high-fat diet (mHFD) and neonatal infections, are increasingly recognized as contributing factors to the development of mood and cognition-related disorders. In parallel, rodent models of mHFD and neonatal infection exhibit behaviors associated with these disorders, …
-
A mouse model of childhood asthma: mechanisms of development and progression following an early-life respiratory viral infection
Background: Lower respiratory tract infections in childhood, including viruses such as respiratory syncytial virus (RSV), are strongly linked to development of allergic asthma. The aim of this project was to develop a mouse model of the induction phase of childhood asthma, to facilitate …
-
Neonatal Sepsis And Antibiotic Sensitivity Patterns At A South African Tertiary Nursery – Evolution Over A 15 Year Period
Background Neonatal infection is an important cause of morbidity and mortality in babies. The causative pathogens and their antibiotic susceptibility patterns should be monitored so that treatment regimens can be adjusted to maintain efficacy and avoid selection of resistant organisms. Objectives …
-
T Cell Responsiveness Through the Ages: Functional Diversity of Age-Dependent Antiviral Responses
… and cell populations in adult severe influenza infection. Single-cell RNA sequencing of tracheal aspirate cells from pediatric subjects experiencing acute respiratory failure (ARF) showed that distinct T cell subsets within the lower respiratory tract exhibited transcriptional similarity, termed …
-
Epidemiologie und Nachweisverfahren von Chlamydia trachomatis bei Neugeborenen und die Behandlung mit Clarithromycin
As infections with Chlamydia trachomatis in neonates are a growing problem and the treatment with Erythromycin frequently shows side-effects and relatively often does not lead to complete eradication, in this prospective study we investigated tolerance and effectivity of the antibiotic therapy with …
-
The formulation and refinement of a polymerase chain reaction (PCR) assay for early diagnosis of paediatric HIV infection and genetic analysis of variants involved in vertical transmission of HIV-1
Paediatric human immunodeficiency virus (HIV) infection has become a major socio-economic health problem in recent years as the number of HIV-1 infected children steadily increases. The majority of these infants are infected through mother-to-child transmission, with the frequency of vertical …
-
Long-term effect of respiratory syncytial virus (RSV) infection on children: a prospective longitudinal birth cohort study in Bangladesh
… of all RSV-associated acute lower respiratory infections (RSV-ALRI) and 99% of RSV-ALRI mortality occurs among children living in developing world countries. Evidence also suggests that children with RSV infection during early infancy are at increased risk for asthma and recurrent wheezing in …