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Showing 1 to 6 of 6 for “"neolignans"”.
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Total synthesis of neolignans.
Thesis. 1978. Ph.D.--Massachusetts Institute of Technology. Dept. of Chemistry.
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New synthetic approaches to 8,5'-neolignans
Neolignans, dehydrodimers of phenylpropenes, are natural products that exhibit different biological activities. 8,5’-Neolignans containing a trans- dihydrobenzofuran skeleton are the most abundant neolignans in nature. The published syntheses of trans-dihydrobenzofurans are multistep procedures …
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Synthesis of lignin-carbohydrate model compounds and neolignans
… are many secondary metabolites such as lignans, neolignans, tannins and terpenoids. The structures of lignans and neolignans are analogous to the interunits of lignin. Lignin is considered an optically inactive polymer, whereas lignans and neolignans are optically active small molecules. Although …
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Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
… strains of Plasmodium falciparum. The 8-O-4' oxyneolignans, dadahols A and B, were identified as the major active compounds using two bioassay-guided fractionation approaches. The new accelerated “HPLC biogram” methodology allowed for early recognition of the active compounds in the complex plant …
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NATURAL OR BIO-INSPIRED POLYPHENOLS IN THE SYNTHESIS OF POTENTIAL CHEMOTHERAPEUTIC AGENTS
… my research activity was devoted to lignans and neolignans, synthetized by chemical and/or enzimatic methodology. Hence, in particular, two polyphenol groups were studied, namely benzoxanthene lignans, their related phenazines and bisphenol neolignans; furthermore during the synthesis of …
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NATURAL POLYPHENOLS AS LEAD COMPOUNDS IN THE SYNTHESIS OF ANTITUMOR AGENTS AND OTHER USEFUL PRODUCTS
… Some polyphenol dimers, such as lignans, neolignans and stilbenoid lignans, because of their biological properties as well as their structural variety, are an attractive target for chemical synthesis or modification. These polyphenols may be considered lead compounds to obtain products …