Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"neoangiogenesis"”.
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Diabete ed ischemia critica degli arti inferiori. Studio del danno della parete arteriosa e del ruolo dell'endotelio circolante nella riparazione tessutale e nella neoangiogenesi
… mature circulating endothelium and the "in situ" neoangiogenesis are related with each other. Design In the peripheral blood of diabetic patients suffering critical ischaemia associated with peripheral artery disease, low levels and poor function of circulating endothelial progenitor cells (EPCs) …
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Effects of light-emitting diode photostimulation on burn wound healing
… deep burn wounds requires restored perfusion and neoangiogenesis to reestablish blood flow and limit ischemic damage.\r\nWe propose that LED photostimulation, by inducing macrophage proliferation and secretion of pro-angiogenic factors, will restore perfusion by increasing angiogenesis. \r\nAn in …
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Development of Hif-1Α/Hif-1Β Heterodimerization Inhibitors Using A Novel Bioluminescence Reporter Assay System For In Vitro High Throughput Screening and In Vivo Imaging
… of HIF-1 signaling-mediated tumor stromal neoangiogenesis.</p>
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Supercritical carbon dioxide-processed resorbable polymer nanocomposites for bone graft substitute applications
… to facilitating cellular infiltration and neoangiogenesis, which are necessary components of bone growth. With the addition of as little as 2.5wt% of nanoclay, the compressive strength of the constructs nearly doubles putting them on par with human cortico-cancellous bone. Rheological …
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Clinical Translation of Optoacoustic Imaging in Breast Cancer
… as surrogate measures of tissue hypoxia and neoangiogenesis, hallmarks of cancer associated with adverse outcomes. The aim of this PhD was to translate optoacoustic imaging into the breast clinic to try and fulfil some of the unmet clinical needs in breast cancer imaging using the imaging …
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Novel Mechanisms of Β-Adrenergic Signaling In Prostate Cancer Progression
… in neuroendocrine differentiation as well as in neoangiogenesis are largely unknown, indicating that the underlying mechanisms of β-adrenergic signaling in prostate cancer progression are far from completely understood. For instance, while the epigenetic regulation by histone deacetylases 2 …
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Differential Angiogenic Capability and Hypoxia Responses in Glioma Stem Cells
… to target GSC-specific molecular mechanisms of neoangiogenesis, including the expression and/or activity of HIF2a.</p>
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STUDY OF THE EFFECT OF TUMOUR EDUCATED MACROPHAGES ON NEURAL CELLS
… extracellular matrix remodelling, and neoangiogenesis, that, while detrimental in cancer, could be harnessed for promoting tissue regeneration following neurotrauma. Moreover, studies conducted in our laboratory further identified that TAMs are endowed with a strong nerve growth …
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Vergleichende Etablierung und Charakterisierung eines orthotopen Kolonkarzinom-Xenograft-Modells
… colon tumors. It was assessed that a broad neoangiogenesis occurred at the beginning of tumor growth prior to the development of metastases. The number of metastases increased with proceeding length of time, whereas the number of vessels decreased. The continuous extension in tumor volume …
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Die Expression von Matrix-Metalloproteasen in humanen Medulloblastomen
Im Rahmen dieser Arbeit wurde anhand von Tumorzelllilien und Nativ-Material untersucht, ob und in welchem Masse Medulloblastome verschiedene Matrix-Metalloproteasen exprimieren. Diese Enzyme spielen bei der Gewebeumstrukturierung und Neoangiogenese im Rahmen der Tumorinvasivität eine wesentliche …
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Investigation of prolactin-related vasoinhibin in sera from patients with diabetic retinopathy
Wissenschaftlicher Hintergrund: In-vitro-Experimente und in-vivo-Studien mit Nagetieren zeigten, dass die N-terminalen 14,15, 16, 17 und 18 kDa-Fragmente (prolactin-related vasoinhibin, PRL-V) des menschlichen Prolaktins natürliche Inhibitoren der Neovaskularisation in der Retina sind. Diese …
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Delayed Thrombus Resolution and Fibroproliferative Vascular Wound Healing From Deficiency of Type Iii Collagen: A Paradoxical Mechanism For Tissue Fragility
<p>Vascular Ehlers-Danlos syndrome is a heritable disease of connective tissue caused by mutations in <em>COL3A1</em>, conferring a tissue deficiency of type III collagen. Cutaneous wounds heal poorly in these patients, and they are susceptible to spontaneous and catastrophic rupture of expansible …