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Showing 1 to 2 of 2 for “"nedd8, ubiquitin"”.
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Investigating the response of the NEDD8 ubiquitin-like molecule to diverse stress conditions
NEDD8 modification of proteins is extensively studied in the recent years, and the ubiquitin-like molecule has been shown to be involved in numerous signalling pathways. In addition to its well-established roles, we showed that NEDD8 responds to various stress conditions, such as inhibition of the …
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Regulation of NEDD8/Rub1 and its substrates
NEDD8 is a small ubiquitin like modifier (UBL) essential for life in almost all known eukaryotes. The primary objective of this work is to determine NEDD8 specific regulatory mechanisms. Like ubiquitin, NEDD8 is first matured and then conjugated via a tripartite conjugation cascade (E1, E2, E3). …