Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"necrotizing fasciitis"”.
-
SRV REGULATION OF STREPTOCOCCAL BIOFILM DISPERSAL AND ITS IMPACT ON VIRULENCE
… GAS also causes severe infections including necrotizing fasciitis. The mechanism for triggering the switch between mild and severe disease has yet to be discovered. Several groups have shown that regulation of protease production may play a role in the transition from localized to systemic …
-
Streptococcal colonization of host mucosal surfaces: a study of biofilm formation and dispersal
… otitis media, sepsis, a toxic-shock syndrome, necrotizing fasciitis, and the post-infectious sequelae acute rheumatic fever and acute rheumatic heart disease. Thus, rather than exploit a singular niche, GAS has evolved to colonize and disseminate within several physiologically distinct …
-
Use of an Animal Model of Group A Streptococcal Infection to Identify Factors Important for Virulence
… from pharyngitis (strep throat) and impetigo to necrotizing fasciitis (flesh eating disease) and streptococcal toxic shock syndrome (STSS). Virulence of the GAS is multifactorial, as it possesses an array of virulence factors regulated in a coordinated fashion by a complement of transcriptional …
-
CcpA-Mediated Carbon Catabolite Repression of Virulence in the Group A Streptoccus
… to the more severe invasive disease such as necrotizing fasciitis. The coordinate expression of a wide array of virulence factors in response to the changing host environment represents a key step in the ability of the GAS to mediate disease in the human host. The present study investigates …
-
Hyaluronate Lyase Gene of <i>Streptococcus pyogenes</i>: Molecular Characterization and Regulation
… of diseases ranging from pharyngitis to necrotizing fasciitis. This bacterium has the ability to elaborate several extracellular products capable of causing tissue damage; one of which is a hyaluronate lyase. Little information is available regarding the regulation of streptococcal …
-
Molecular and microscopical analysis of pathogenic streptococci - studies on surface proteins interacting with human cells and extracellular matrix
… of causing severe invasive disease such as necrotizing fasciitis, sepsis and toxic shock. Until recently, S. pyogenes has been considered as a strictly extracellular pathogen, but several studies has shown that it is capable of invading and surviving intracellularly in several human cell …
-
Actions of Antimicrobial Peptides and Bacterial Components in Inflammation
… like streptococcal toxic shock syndrome and necrotizing fasciitis. We found that M1 protein is able to induce vascular nitric oxide (NO) production, which in turn relaxes smooth muscle cells and could thereby contribute to the severe hypotension seen in septic patients. This we confirmed by …
-
Valor predictivo del índice de severidad para gangrena de fournier en el Hospital Universitario de la Samaritana
La GF es una infección fulminante, afecta cualquier edad y género. Se ha descrito el índice de severidad de gangrena de Fournier (ISGF), el cual es útil para evaluar el pronóstico de estos pacientes. OBJETIVO. Reportar nuestra experiencia con esta patología en los últimos 12 años y evaluar el valor …