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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 862 for “"necrosis"”.
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Induction of Apoptosis and Necrosis By Infectious Pancreatic Necrosis Virus in Chinook Salmon Embryo Cells
… associated with the induction of apoptosis or necrosis in the cells they infect. Infectious Pancreatic Necrosis Virus (IPNV) is a birnavirus that has been shown to cause severe necrosis in pancreatic, intestinal epithelial, kidney, and liver tissues in infected salmonid fish, but no research …
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An Investigation Into the Replication of Satellite Tobacco Necrosis Virusand Tobacco Necrosis Virus Rna Genomes
Made available in DSpace on 2015-05-14T14:57:09Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7219850.PDF: 3567601 bytes, checksum: ed569906a56663cd6e6ec4ea11683fe4 (MD5) Previous issue date: 1972
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Engineering resistance to maize lethal necrosis
… of an emerging maize disease, Maize lethal necrosis (MLN), and engineering resistant maize lines using an artificial microRNA (amiRNA) approach. MLN is a synergistic viral disease caused by the interaction of Maize chlorotic mottle virus (MCMV) with any maize-infecting member of the …
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Acetaminophen-induced hepatic necrosis: possible biochemical mechanisms
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Initial Characterization of Attachment of Infectious Pancreatic Necrosis Virus
Infectious Pancreatic Necrosis (IPN) virus is an economically important pathogen of young, hatchery-reared trout. Little information is available on the early steps of IPN virus infection. In this study a method of assaying attachment of IPN viruses to Chinook Salmon Embryo (CHSE) cells was …
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Interactions of viral and cellular Tumour Necrosis Factor Receptor molecules
Tumour necrosis factor (TNF) is potent pro-inflammatory and anti-viral cytokine, acting via two cellular receptors, TNFR1 and TNFR2 that induces apoptosis and inflammation. Poxviruses encode homologues of TNF-receptors (viral TNFRs) that independently interact with both TNF, and simultaneously with …
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Molecular characterization of the cucumber necrosis virus coat protein gene
A cucumber necrosis tombusvirus (CNV) mutant which lacks the coding sequence for the coat protein protruding domain, PD(-), was constructed by site-directed mutagenesis of an infectious CNV cDNA clone, pK2/M5 (wild-type, 4701 nt). Transcripts of PD(-) were infectious in Nicotiana clevelandii, …
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An Investigation of the Chemical Structure of the Tobacco Necrosis Virus
Made available in DSpace on 2015-05-13T22:12:03Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7000910.PDF: 3745751 bytes, checksum: 6d9c2ffad15f980aa6837889edbca6ae (MD5) Previous issue date: 1969
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The Translation Initiation Site of Satellite Tobacco Necrosis Virus Ribonucleic Acid
Made available in DSpace on 2014-12-14T04:27:44Z (GMT). No. of bitstreams: 1 7820992.pdf: 3932031 bytes, checksum: 690377f344e58a40a49920b99f49c741 (MD5) Previous issue date: 1978
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The in Vitro Translation of Satellite Tobacco Necrosis Virus Ribonucleic Acid
Made available in DSpace on 2014-12-10T23:24:30Z (GMT). No. of bitstreams: 1 7405610.pdf: 4293299 bytes, checksum: f4f05f2afd28024a6feabb1e507e732a (MD5) Previous issue date: 1973
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Evaluation of translation initiation features of satellite tobacco necrosis virus RNA
Satellite tobacco necrosis virus RNA (STNV RNA) is an unusual mRNA that is efficiently translated in the absence of a 5$\sp\prime$-terminal cap structure and initiator AUG codon. The translational properties, in wheat germ in vitro translation system, of transcript STNV RNAs (tSTNV RNAs), with …
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The protective role of tumour necrosis factor alpha in the heart
The pleiotropic cytokine tumour necrosis factor alpha (TNFα) is produced by the heart in response to the ischaemic preconditioning (PC) stimulus. We hypothesised that this endogenously produced peptide may play a role in activating the ischaemic PC mediated tolerance towards a subsequent ischaemic …
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Efecto de ceramidas sintéticas sobre la inducción de necrosis en células HTC
… muerte celular, como la apoptosis, autofagia y necrosis, presentando cada uno características morfológicas y moleculares diferentes. Se ha considerado a la necrosis como un mecanismo de muerte celular “accidental” y, por tanto, menos regulado. Sin embargo existen evidencias de que la necrosis …
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The mechanism of action of tumour necrosis factor-α / Jeffrey A.J. Barbara.
The in vivo adminstration of Tumour Necrosis Factor-alpha as an antineoplastic agent has been severely restricted by dose-limiting side effects. Human TNF mutants with selective binding to the Human TNF receptors were employed to examine the role of these receptors in the mediation of TNF's …
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Role of Tumour Necrosis Factor Alpha (TNFa) in ischaemic and pharmacological postconditioning
Ischaemic postconditioning (IPostC) is a powerful protective mechanism that activates prosurvival intrinsic signalling cascades to limit reperfusion injury but the exact signalling pathway involved in this cardioprotective effect still remains unclear.
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Determining the Roles of Q-SNAREs in Mast Cell Tumor Necrosis Factor Exocytosis
<p>As evidence accumulates on the contributions of mast cell function to the development of allergic disorders, cardiovascular and neurological pathologies, and cancers, there is a growing recognition of the importance of mast cell-derived TNF to mast cell-mediated pathophysiology. However, our …
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The Role Of Adult Stem Cells And Tumor Necrosis Factor In Peripheral Neuropathy
… of gene microarrays. We found that Tumor Necrosis Factor (TNF) mediates axonal-Schwann cell communication, and that disruption of TNF signaling results in sensory and tissue dysfunction. These findings indicate that the threshold of wild-type physiological function in peripheral nerve …
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Treatment of arthritis with tumour necrosis factor antagonists. Clinical, immunological and biochemical aspects
… the disease process have been introduced. Tumour necrosis factor (TNF) antagonists have been shown to reduce signs and symptoms of disease and to retard the development of tissue damage in the majority of patients. This thesis focuses on clinical, immunological and biochemical aspects of treatment …
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