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Showing 1 to 5 of 5 for “"natural inhibitors"”.

  1. Abdominal aortic aneurysms : identification by self-examination and analysis of variation in matrix metalloproteinases with peak wall stress

    … concentration is elevated and levels of their natural inhibitors - Tissue Inhibitors of Matrix Metalloproteinases (TIMPs) are reduced at sites of AAA rupture. Finite element analysis (FEA) of AAAs can define the area of peak wall stress area, the most likely site of rupture in engineering …

    hull Repository record for Abdominal aortic aneurysms : identification by self-examination and analysis of variation in matrix metalloproteinases with peak wall stress (opens in a new tab)

  2. Isolation And Characterization Of Natural Alpha-Glucosidase Inhibitors From Antioxidant Rich Red Wine Grapes (vitis Vinifera)

    … of the isolated active components as natural inhibitors of alpha-glucosidases. </p> <p> <strong>Methods:</strong> Chambourcin, Merlot, Norton, Petit Verdot, Syrah and Tinta Cao red wine grape pomace extracts were assessed for their rat intestinal alpha-glucosidase inhibiting activity …

    wayne-thes Repository record for Isolation And Characterization Of Natural Alpha-Glucosidase Inhibitors From Antioxidant Rich Red Wine Grapes (vitis Vinifera) (opens in a new tab)

  3. Design of Non-ATP Competitive and Cell Cycle Specific CDK Inhibitors Targeting Cyclin Binding Groove

    … ATP competitive compounds being the most common inhibitors. However, issues arising from the selectivity of current inhibitors have prevented clinical validation of these important targets. To generate cell cycle specific CDK inhibitors with high selectivity, an alternative way of designing CDK …

    south-carolina Repository record for Design of Non-ATP Competitive and Cell Cycle Specific CDK Inhibitors Targeting Cyclin Binding Groove (opens in a new tab)

  4. Identifying a Target Protein and Ligands for Autoimmune Disorders

    … binding cavities of HIF-1in complex with 140,00 naturally occurring products from Coconut Database. Three suitable drug candidates for SLE were identified, all from different chemical classes and plant species.</p>

    chapman Repository record for Identifying a Target Protein and Ligands for Autoimmune Disorders (opens in a new tab)

  5. The in vitro effects of chemokines on microglia: Implications for multiple sclerosis.

    … as the balance between MMP and levels of their natural inhibitors, TIMPs, may determine lytic or anti-lytic activity in MS. The in vitro control of MMPs 2 and 9, TIMPs 1 and 2 and urokinase type plasminogen activator (uPA) by microglia was examined in response to several chemokines using ELISA …

    sheffield-hallam Repository record for The in vitro effects of chemokines on microglia: Implications for multiple sclerosis. (opens in a new tab)