Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"natural competence"”.
-
Expanding the Genetic Toolkit of Fusobacterium nucleatum by Generation of Fully-Sequenced Genomes and Discovery of Natural Competence
… my discovery of DNA uptake machinery involved in natural competence and transformation in F. nucleatum. This work is the first to characterize natural competence in a Fusobacterium species, and also enables the expansion of Fusobacterium genetics utilizing the newly found competence mechanism. The …
-
Molecular dissection of competence regulated virulence in Streptococcus pneumoniae
… pathogen capable of entering the competent state naturally and acquiring DNA from the environment for recombination. In addition to improving genome plasticity, a natural competence system directly contributes to pneumococcal virulence during pneumonia and bacteremia, independent of DNA uptake. …
-
Recruitment and Mechanism of the Bacterial Type IV Pilus Motors
… type IVa pilus system can be used for adhesion, natural competence, phage adsorption, folded-protein secretion, surface sensing, and surface associated motility. Likewise, it is a major virulence factor in many bacterial pathogens. This system extends and retracts a thin and long protein fibre …
-
Facultative sex in bacteria: Origin, timing and function
… three subjects: the timing of a sexual process, natural genetic transformation, in the bacterium Bacillus subtilis, the relationships between sex, dispersal and dormancy in a variety of organisms, and the evolutionary history of natural genetic transformation, in all living things. My …
-
Genetic mechanisms contributing to antimicrobial resistance: gene repression in Mycobacterium, gene transfer in Salmonella, and phage sensitivity in Escherichia
… intracellulare, regulation mechanisms of natural competence in Salmonella Typhimurium, and phage therapy of Enterohemorrhagic Escherichia coli serogroup O157:H7. A recent study showed specific mutations in the uncharacterized locus mmpT5 increased resistance to anti-TB drug bedaquiline in …
-
Characterisation of the ATP-dependent ligase, Lig E: An investigation into its significance in Neisseria gonorrhoeae
… a role in both biofilm formation and bacterial competence, both of which would be greatly beneficial for the persistence and acquisition of antibiotic resistance genes in N. gonorrhoeae. In this thesis, I focussed on characterising Lig E from N. gonorrhoeae (Ngo-Lig E) to determine its …
-
Coexistence of paralogous quorum sensing systems leads to diverse network topology for coordinating competence and bacteriocin biosynthesis in cariogenic streptococci
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-05-01
-
Komparative Genomanalyse zur Stammoptimierung produktionsnaher Bacillus-Stämme
B. licheniformis DSM13 ist ein gram+ , ubiquitär vorkommendes, sporenbildendes Bakterium, das in großem Maßstab für die industrielle Produktion von Exoenzymen eingesetzt wird, weil es hohe Proteinmengen sekretieren kann. Das Genom wurde 2004 im Göttinger Genomlabor sequenziert. Seit der …