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Showing 1 to 5 of 5 for “"nanopipette"”.
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Anwendungen der Ionenleitfähigkeitsmikroskopie in der Biophysik
… kann das SICM über die funktionalisierte Nanopipette mit einem Öffnungsdurchmesser von 60 nm auch als aktiver Manipulator von weichen Proben eingesetzt werden. Die Kombination von Fluoreszenzmikroskopie und SICM bietet daher vor allem für die Biophysik neue Möglichkeiten der Beobachtung …
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Development of novel imaging technology to study cell signalling
… (ldSPIM) to address this issue. ldSPIM uses a nanopipette to accurately deliver individual proteins to a defined position. For single-molecule fluorescence detection, we implemented single-objective SPIM using a reflective atomic force microscope cantilever to create a 2 μm thick light sheet. …
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Ion flow and membrane tension studies with optical tweezers and nanopipettes
… the studies this has enabled. Optical tweezers, nanopipettes, and fluorescence were all combined to study the effect of salt species on nanoscale voltage driven flows, the mechanical behaviour of cell membranes, and the electrical activity from various cells. Voltage driven, or electroosmotic, …
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A cylindrical specimen holder for electron cryo-tomography
The ‘missing wedge’ is a long-standing problem in electron tomography, caused by the use of slab-like flat specimens, which increase in thickness when tilted to high angles. Attempts have been made to reduce the undesirable effects caused by the missing wedge, but the problem remains, particularly …
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Nano-pipette as nanoparticle analyzer and capillary gated ion transistor
<p>The ability to precisely count inorganic and organic nanoparticles and to measure their size distribution plays a major role in various applications such as drug delivery, nanoparticles counting, and many others. In this work I present a simple resistive pulse method that allows translocations, …