Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"nanomachine"”.
-
Artificial and natural nucleic acid self assembling systems
<p>Nucleic acids are good candidates for nanomachine construction. They participate in all the processes of life, and so can function as structural building blocks and dynamic catalysts. However, to use nucleic acids as nanomachines, a better understanding of their material properties, how to …
-
Channel modeling of multilayer diffusion-based molecular nano communication system
… encoded into molecule patterns by a transmitter nanomachine, has emerged as a promising communication system, particularly for biomedical and healthcare applications. Although, numerous studies have been conducted to evaluate and analyze DBMC systems, investigation on DBMC system through a …
-
Optimizing the Toehold-Mediated Strand Displacement Reaction on the Nanoparticle Surface by Altering the Surface DNA Density for the Design of a microRNA NanoOptical Sensor
… that underpins various sensing and DNA-driven nanomachine applications. This fundamental understanding allowed the design of a label-free, low cost and miniaturized biosensing platform based on the disassembly of core-satellite nanoassemblies. We successfully manipulate the system for the rapid …
-
Understanding PilB, The Type IV Pilus (T4P) Assembly ATPase
… of many bacterial groups. T4P is a versatile nanomachine; it plays many important roles such as for surface attachment, virulence factor, and surface motility apparatus. This research focuses on understanding the kinetics of PilB, the T4P assembly ATPase. PilB crystal structure exhibits an …
-
Interferometric Scattering Microscopy: Theory, Simulation, and Experiment
How fast does a nanomachine move? Can we watch it moving, if we can see it at all? What types of movements can we track at the nanoscale, and to what degree of spatial and temporal precision? My thesis seeks to develop the necessary theoretical and experimental framework to answer these questions …
-
The Role of a Neuron-Specific V-ATPase in Synapse Specification, Function, and Maintenance
… triphosphatase (ATPase) is a proton-pumping nanomachine consisting of two multi-subunit, reversibly associating protein sectors, the cytosolic V1 sector and the membrane-bound Vo sector. The V1/Vo holoenzyme hydrolyses ATP to translocate protons across biological membranes thereby modulating …
-
Synchrony of harmony and chaos in a dynamic, bacterial riboregulatory machine
… its impact on the ensemble organisation of the nanomachine 4. Finally, the last chapter focuses on the interaction between the RNA degradosome with ribosomes and translating polysomes. The interactions are studied at different stages of transcription in vitro and a hypothesis made that these may …
-
Characterization of Novel Type VI Effectors of Acidovorax citrulli and Their Applicability to Biological Control of Plant Diseases
… systems, the Type VI Secretion System (T6SS), a nanomachine widely distributed in Gram-negative bacteria, is gaining increasing attention due to its involvement in microbe-microbe and microbe-host interactions through secreting toxins into host cells, microbial competitors, and the extracellular …
-
DNA Origami Mechanisms and Machines
… design and assembly of higher order controllable nanomachines. This work has the potential of initiating a new era of nanorobot design useful for applications including drug delivery, biosensing, and nanomanufacturing.