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Showing 1 to 20 of 31 for “"nanocarrier"”.

  1. Designing a safe dendronised polymeric nanocarrier for hydrophobic drugs or gene delivery in cancer therapy

    Wali, Aisha Roshan MohamedUniversity of Wolverhampton2018

    … the P-PLLA, P(Lac)-PLLA, PSS-PLLA and P-OGPLLL nanocarriers serve as a reliable drug/gene delivery nanoplatform to enable the improvement of the bioavailability, targetability, efficacy and overcome MDR of therapeutic agents.

    wlv Repository record

  2. Developing Photo-responsive Metal-Organic Frameworks towards Controlled Drug Delivery

    Epley, Charity CherieVirginia Tech2017

    … while it is important to ensure strong drug-nanocarrier interactions, the nanocarrier must be able to release the drug when it has reached its biological target. We have developed a nanocarrier that provides a platform for drug systems that could achieve this drug release via the use of a …

    vt Repository record

  3. Nanotechnology based therapeutic approaches to iron‐induced oxidative stress in an in vitro model of Parkinson’s disease

    Mursaleen, L.University of Westminster2021

    … be overcome. This study aimed to develop novel nanocarrier delivery systems of the antioxidants curcumin, n‐acetylcysteine (NAC) and hydroxytyrosol (HT), alone or combined with the iron chelator deferoxamine (DFO), to protect against rotenone‐induced parkinsonism in SH‐SY5Y cells, and in a …

    westminster Repository record

  4. Polyethylene glycol copolymer nanocarriers: Biocompatibility, uptake and intracellular trafficking in neurons

    Veettil, RemyaTexas Woman's University2017

    … nanomaterial-based drug delivery systems (nanocarriers) are promising excipients for targeted drug delivery to neurons. We have developed four types of nanocarriers and performed experiments to further optimize their potential use in SCI treatment. One of them is a polymer (PEG copolymer) …

    twu Repository record

  5. Avaliação do uso de nano carreadores de ramnolipídeos associados ao fotossensibilizador azul de Taylor na terapia fotodinâmica antimicrobiana contra Staphylococcus aureus: estudo in vitro

    Jesus, Romário Santiago deUniversidade Federal da Bahia2025

    … blue (DMMB, λ ≈ 656 nm) and rhamnolipid nanocarriers (RL-NPs) produced by Pseudomonas aeruginosa. Seven experimental groups were established: Control (no treatment); LED (irradiation only, 20 J/cm²); DMMB (300 ng/mL); RL-NPs (300 ng/mL); RL-NPs/DMMB (300 ng/mL); PDT (DMMB + LED); and …

    brazil-ufba Repository record

  6. Modulating macrophage phenotype for obesity therapy

    Gonzalez Medina, Natalia YaratzethUniversity of Illinois Urbana-Champaign2025

    … The Smith Lab at Illinois has shown dextran nanocarriers to be effective carriers for the delivery of anti-inflammatory drugs to adipose tissue. However, it is unclear which types of anti-inflammatory pharmaceutical drugs are most effective for modulating adipose tissue macrophages and how …

    uiuc Repository record

  7. Design, Synthesis and Characterization of Photoactivable Cyclodextrin-Based Nanoparticles for Multimodal Anticancer Therapy

    KANDOTH, NOUFALUniversità degli studi di Catania2012

    … as the building block for the development of the nanocarrier in order to convey the therapeutic payload to the desired site. With this goal in mind, we have developed several kinds of nanosystems and are discussed in each chapter. The entire dissertation is divided into four sections based on the …

    catania Repository record

  8. Stimuli-Responsive Polymer Systems that Respond to Redox Potential and pH for Controlled Drug Release

    Elkassih, Sussana Ahmed2020

    Nanocarriers are widely investigated drug delivery systems that can overcome physiological barriers by tuning nanocarrier size, shape, surface chemistry, targeting ligand conjugation, and material composition. Furthermore, they have stimuli-responsive moieties that translate physiological signals, …

    utswmed Repository record

  9. NANOFORMULATION OF BUDDLEJA DAVIDII EXTRACT: DEVELOPMENT AND CHARACTERIZATION OF LIPOSOMES AND NANOFIBERS FOR WOUND HEALING APPLICATION

    YASMIN, ADEELAUniversità degli Studi di Cagliari2026

    … was used as a potential wound healing agent in nanocarrier formulations for targeted delivery. We aimed to present a literature review, as well as experimental approaches involving two different nanocarrier formulations: liposomes and electrospun nanofibers, in understanding their impact on the …

    cagliari Repository record

  10. Engineering bacteriophage nanocarriers for targeted delivery of protein reagents to prostate cancer cells

    DePorter, Sandra M., author, McNaughton, Brian, advisor, Kennan, Alan, committee member, Crans, Debbie, committee member, Reynolds, Melissa, committee member, Di Pietro, Santiago, committee memberColorado State University. Libraries2014

    … challenge, we have developed a bacteriophage nanocarrier to deliver large payloads of proteinaceous cargo to the interior of prostate cancer cells. This reagent employs two distinct components: a genetically defined prostate cancer cell-selective protein transduction domain, and a …

    colostate Repository record

  11. Sviluppo di nanomedicine per la somministrazione oculare di farmaci

    ROMEO, ALESSIAUniversità degli studi di Catania2022

    … enzimatica. Le modifiche della superficie dei nanocarrier consentono di bypassare le barriere oculari, migliorando la penetrazione e garantendo un'efficace somministrazione di farmaci ai tessuti target intraoculari. Pertanto, la composizione dei nanocarrier gioca un ruolo fondamentale nello …

    catania Repository record

  12. Self-assembly of bioactive or electrocatalytic polyaspartamide nanoparticles

    Lai, Mei-HsiuUniversity of Illinois at Urbana-Champaign2015

    … to assemble bioactive or electrocatalytic nanocarriers were proposed to dates; however, most approaches accompany complex chemistry and multiple purification, thus reducing production yield while increasing costs. Therefore, the goal of this thesis research was to develop a simple but …

    uiuc Repository record

  13. Light and nanoparticle-based approaches to the control of ion channels and drug delivery

    Febvay, Sébastien, 1976-Massachusetts Institute of Technology2016

    … to obtain a highly stable and targetable nanocarrier, and used an embedded photosensitizer to combine the power of targeted delivery with the spatiotemporal control of light activation. NP-mediated endosomal disruption can be controlled at the single vesicle level. As an example, we …

    mit Repository record

  14. Synthesis and Characterization of Poly(lactide) Functional Oligomers and Block Copolymers

    Kayandan, SanemVirginia Tech2013

    … block copolymer was used as a polymeric nanocarrier to encapsulate the HIV protease inhibitor, Ritonavir, within magnetite nanoparticles. Well-defined multifunctional polymeric nanoparticles with controlled sizes and size distributions were fabricated by rapid nanoprecipitation using …

    vt Repository record

  15. Dendrimer Nanoconjugates And Their Oral Inhalation Formulations For Lung Cancer Therapy

    Zhong, Qian2015

    … challenges, we used a strategy — polymeric nanocarriers (PNCs) to achieve the spatial and temporal drug release and local delivery of drug to the lungs. In this work, we desgined polyamidoamine dendrimer (PAMAM) conjugates which can only release DOX intracellularly, while being stable in …

    wayne-thes Repository record

  16. Design, Development and Evaluation of Dual Drug Nanomedicine for Non-Small Cell Lung Cancer

    Hatami, Elham2022

    … method. In this platform, HTA is a biocompatible nanocarrier that binds to both GA and Gem. Physico chemical characterizations studies revealed that GA and Gem are successfully encapsulated in HTA NPs with uniform spherical morphology. These nanoparticles were readily taken up by NSCLC cells (A549 …

    tenn-hsc Repository record

  17. Development of nanoscale biosensors for cancer related proteases and blood-borne pathogens based on electrochemical and optical methods

    Swisher, Luxi ZhangKansas State University2015

    … gold nanoparticles (GNPs) served as a nanocarrier for enhancing CL signal. The CL signal can be observed over 8 orders of magnitude variations in GNP concentration. Using the same number of particles, luminol-labeled 30-nm-diameter latex beads showed ~3 orders of magnitude higher CL …

    ksu Repository record

  18. A Green Light at the Intersection of Metal-Organic Frameworks and Drug Delivery

    Cornell, Hannah D.Virginia Tech2022

    … the important role of host–guest interactions in nanocarrier development. Holistically, this work highlights the promise of stimuli-responsive MOFs as drug delivery platforms.

    vt Repository record

  19. DESIGNING BIOMIMETIC NANOPARTICLES TO TACKLE INTRACELLULAR PATHOGENS

    DAD, HASEEB ANWARUniversità degli Studi di Milano2025

    … these limitations, we developed a biomimetic nanocarrier platform termed Nanoghosts (NGs), derived from the plasma membranes of human monocytes (THP-1 cells and primary CD14+ monocytes). These NGs were designed to retain key membrane features while excluding nuclear and cytoplasmic content, …

    milano Repository record

  20. Excessive iron accumulation mediated oxidative stress and β-cell dysfunction via perturbations of insulin secretion in MIN6 cells

    Blesia, V.University of Westminster2020

    … ferritin were assessed using the shell of nanocarriers composed of (i) potato protein (PP) - potato dextrin (PD), (ii) PP - modified citrus pectin (MCP) used to formulate Fe and hesperetin in the presence/absence of EGCG. These experiments were followed by assessments of cellular iron …

    westminster Repository record

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