Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"nano-bio interface"”.
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Hard and soft coatings on gold nanoparticles at the nano-bio interface
… dissertation explores surface chemistry of gold nanoparticles, with a special focus in developing analytical methods to decipher the environment of small molecule ligands and biomolecule coronas at the molecular level. Chapter 1 introduces the physical and chemical properties of gold …
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Investigating lipid corona formation onto polystyrene nanoparticles through fluorescence correlation spectroscopy
When a nanoparticle enters a biological environment, molecules are known to adsorb on the surface forming a corona. Systematically studying the formation of a corona is important to develop knowledge as to how a given nanomaterial will transform once entering a biological environment. A common …
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Multimodal Optical Interfaces Enabled by Multiresonant Plasmonics for Bio-Nanophotonics
Engineering tools at the nano-bio interface have enabled transformative advances in molecular diagnostics, therapeutic monitoring, and cellular manipulation. However, challenges remain in achieving continuous real-time sensing, intracellular probing, and controlled actuation within an integrated, …
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Single-molecule methods for an improved understanding of biophysical interactions: from fundamental biology to applied nanotechnology
… The information that can be gained by studying biological systems on a single-molecule scale, in the absence of ensemble averaging, provides an unprecedented amount of detail about molecular interactions in real-time. Single-molecule biophysical techniques have provided unique insights into the …
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Hybrid organic-inorganic nanomaterials for applications at the biointerfaces
In the last few years, the application of nanomaterials (NMs) as theranostic devices, which combine diagnostic and therapeutic features, has gained a tremendous interest and development. Still, the major challenge is the understanding of the many and often complex processes that occur during the …
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High-throughput plasma nanomanufacturing and its applications
Traditional top-down or bottom-up nanomanufacturing processes involve nanoscale pre-patterning, surface-area-sensitive assembly processes or extreme fabrication conditions; therefore, none of them meets the requirements of scalable and translational nanomanufacturing processes in one or more …
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Bio-interfaced Nanolaminate Surface-enhanced Raman Spectroscopy Substrates
… from plasmonic hotspots of noble metal nanostructures. Label-free SERS has attracted tremendous interest in bioanalysis over the last two decades due to minimal sample preparation, non-invasive measurement without water background interference, and multiplexing capability from rich …
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Quantification of molecular-level events at nanoparticle-biological interfaces
Nanomaterials exhibit various interesting and fundamental properties that are distinctly different from their bulk or molecular scale counterpart. The fascinating size- and shape-dependent optical properties of gold nanoparticles, in particular, along with highly tunable sizes and shapes as well as …
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Implications of nanoparticle-protein interactions on protein assembly and conformation
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01
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Investigating the impact of gold nanoparticles on cells: from transcription to behavior
Gold nanoparticles (Au NPs) are being research extensively for various biomedical applications; their applicability arises from a unique set of optical and physical properties brought on by their nanoscale dimensions.1 Furthermore, facile and scalable synthetic and surface functionalization …
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Advancing Nanoplasmonics-enabled Regenerative Spatiotemporal Pathogen Monitoring at Bio-interfaces
… continuous spatiotemporal pathogen monitoring at biological interfaces (e.g., human tissue) holds promise for transformative applications in personalized healthcare (e.g., wound infection monitoring) and environmental surveillance (e.g., airborne virus surveillance). Despite notable progress, …