Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 17 of 17 for “"naïve patients"”.
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Incidence and Prevalence Of Renal Dysfunction In Antiretroviral Therapy (ART) Naïve Patients Starting A Tenofovir (TDF) Based ART Regimen In Mitchell's Plain Community Health Centre (CHC) ARV Clinic
… and associated factors of nephrotoxicity in patients initiated on TDF based ART regimen in Mitchell's Plain CHC ARV Clinic and make recommendations. Methodology: The study was conducted by reviewing retrospective records of all ARV naïve HIV positive adults initiated on TDF based ARV regimen …
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Clinical Course of Partial Virological Responders
… study aimed to assess the clinical course of PVR patients receiving ETV therapy and analyze the efficacy of tenofovir (TDF). We retrospectively evaluated 130 patients who showed a PVR to ETV. Among these patients, 102 were nucleot(s)ide analogue (NUC)-naïve and 28 were lamivudine …
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The Strategic Value Driver Model: a Methodology for Examining Value Drivers for a New Pharmaceutical Product in Diabetes
… used to collect a sample of 483 Type 2 diabetic patients via national panel of diabetic patients. The sample had two subgroups—insulin-naïve (52.9%, n=255) and insulin-user (47.1%, n=227) patients. The comparative performance of insulin syringes/vials, insulin pen and inhaled insulin was captured …
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The Association of Prescription Opioid Exposure and Patient Factors with Prolonged Postoperative Opioid Use in Opioid Naive Patients
… opioid use occurs in 4-13% of opioid naïve patients and is related to factors other than surgical pain. However, it is unclear which patient factors and prescribing practices are associated with prolonged use after surgery among opioid naïve patients.</p> …
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HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy
… of cognitive impairment at baseline in HAART-naïve patients, and whether initial levels of these biomarkers related to the change in cognitive function a year later.
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Investigating the Immunological Effect of Schizophrenia-Related Antigens and Anti-psychotic Medication.
… antibodies against selected target molecules in patients with schizophrenia and control subjects. Six peptide antigens derived from DPYD, MAD1L1, ZNF804A, DRD2, TRANK1 and MMP16 showed an increase in plasma IgG levels and three derived from TSNARE1, TCF4 and VRK2 showed a decrease. As the initial …
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Investigating high-density lipoprotein (HDL) subfractions, composition and functionality in people living with HIV
… Methods: Fifty healthy HIV-negative control patients (HIV free control), 44 HIV-infected patients yet to receive any ART treatment (HIV ART-naïve) and 50 HIV-infected patients receiving ART (ART-treated) were included (South African cohort). HDL functionality was assessed by measuring reverse …
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Patterns and associations with immunologic response in patients accessing ART in Khayalitsha
… study describing the outcomes of treatment of patients accessing ART in Khayelitsha. Despite the reported favorable outcomes in terms of immunologic responses, the actual variations in patterns of and associations with immunologic response over time among adult patients accessing the community …
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Mechanism of lipid disorder in HIV infection: apolipoprotein-B kinetics, fat distribution, insulin resistance and adipocytokines in patients taking protease inhibitors or non-nucleoside reverse transcriptase inhibitors
… in 12 HIV negative controls and 55 HIV-infected patients including antiretroviral treatment-naïve patients (n=15) and patients taking two nucleoside analogues plus either a protease inhibitor (PI, n=15) or non-nucleoside reverse transcriptase inhibitor (NNRTI, n = 25). The HIV positive treatment …
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Exploring the genetic landscape in cutaneous T-cell lymphoma with short- and long-read sequencing
… about the genetic changes in early and treatment-naïve patients, which makes a correlation between genetics and variable disease progression impossible.<br /> In this work, the copy-number landscape of the rare CTCL subtype, Sézary syndrome, was further detailed using whole-exome sequencing data, …
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Detecting prostate cancer metastases - PET/CT and the sentinel node technique
… clinical implications of early choline PET/CT in patients with biochemical recurrence (BCR) after radical prostatectomy (RP) was evaluated in Study III. SN detection was prospectively evaluated and compared with ePLND in Study IV. The main results were: 1) A fifth of patients with high-risk …
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Long-Term Opioid Prescribing among Patients Living with Metastatic Cancer as a Chronic Disease
Patients living with metastatic cancer often experience pain which requires involvement of palliative care and symptom management teams. Opioids are a commonly used tool for the treatment of this cancer-related pain. While opioids serve an important purpose in symptom management and end-of-life …
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Identifying circulating biomarkers in a cohort of hypercholesterolaemic patients with statin intolerance from Gauteng, South Africa
… infarction or stroke. However, a proportion of patients do experience statin associated adverse effects, especially muscle related symptoms. Studies suggest that statins affect hundreds of miRNAs, as one miRNA has the potential of binding to hundreds of mRNAs, the consequences may be enormous. …
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Erectile dysfunction in clinical practice. - With special focus on the correlation to myocardial infarction, lower urinary tract symptoms (LUTS), treatment cost and optimization -
… treatment costs and optimization. A group of 100 patients under the age of 70 years who had suffered their first MI and an age matched control group without MI answered a questionnaire regarding ED and concomitant diseases. The aim was to evaluate the possible connection between ED and …
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Clinical Application of Prognostic Factors and Their Integration in a Risk and Time to Treatment Assessment Scale for Treatment-Naive B-CLL Patients // Клинично приложение на прогностичните фактори и интегрирането им в скала за оценка на риска и времето до лечение, при нелекувани пациенти с В-хронична лимфоцитна левкемия
Хроничната лимфоцитна левкемия е една от най- честите левкемии при възрастни, характеризираща се с изключително променлив клиничен курс и различен изход на заболяването, дефинирани от множество фактори свързани със сложните патогенетични процеси протичащи в неопластичните клетки. Темата на …
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Investigating prescribers' experiences of direct-acting oral anticoagulants for the management of nonvalvular atrial fibrillation.
… for stroke and systemic embolism prevention in patients with non-valvular atrial fibrillation (AF) and have replaced warfarin as the first line agent of choice. The aim of this research was to determine prescribers' views and experiences of the use of DOACs for the management of non-valvular AF. …
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Modelo de pronóstico para mejorar la efectividad en los medicamentos de los tratamientos antivirales en VIH
Introducción: En Colombia los tratamientos para el virus de inmunodeficiencia humana, consumen gran parte del presupuesto en salud, debido a que el costo es directamente proporcional al tiempo de supervivencia del paciente, por esto los tratamientos más eficaces no están al alcance de toda la …