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Showing 1 to 20 of 32 for “"n-3 PUFA"”.
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Regulation of n-3 PUFA biosynthesis in proliferating and differentiated PC12 pheochromocytoma cells
Regulation of polyunsaturated fatty acid (PUFA) biosynthesis in proliferating and NGF-differentiated PC12 pheochromocytoma cells deficient in n-3 docosahexaenoic acid (DHA, 22:6n- 3) was studied. A dose- and time dependent increase in eicosapentaenoic acid (EPA, 20:5n-3), docosapentaenoic acid …
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Long Chain n-3 PUFA and Oleic Acid Modification Strategies to Enhance Fillet Quality in Tilapia, Oreochromis species
Tilapia are freshwater fish that have become important in aquaculture and as a stable global source of seafood due to their ability to thrive in different environments. However, tilapia are sometimes considered nutritionally undesirable due to their high n-6 to n-3 fatty acid ratios. A market study …
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Pasture feeding impacts on lamb lipid composition and on blood plasma and cardiovascular risk factors in humans
… focusing on increasing levels of omega-3 (n-3 PUFA) in lamb. The impact of diet on n-3 PUFA composition of lamb meat was evaluated using a systematic review and meta-analysis. Results reinforced the benefits of pasture feeding on n-3 PUFA, particularly C18:3 n-3 and more uniquely C20:5 n-3 in …
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Fatty acid regulation of adhesion molecule expression in human vascular cells.
… consumption of n-3 polyunsaturated fatty acids (PUFA) from fish and fish oil have been shown to play an important role in the amelioration and prevention of cardiovascular disease and a number of inflammatory disorders. Similarly, conjugated linoleic acids (CLAs) from dairy products and the meat …
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The effect of omega-3 fatty acid supplementation and transcranial direct current stimulation on plasma cytokines
… of omega-3 polyunsaturated fatty acids (n-3 PUFA) and Transcranial direct current stimulation (tDCS), on plasma inflammatory cytokines as an assessment of potential neuro inflammation. Migraine is a common disabling brain disorder influencing physical, mental, and social dimensions of quality …
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ESTABLISHING IN VITRO INTESTINAL EPITHELIAL CELL MODELS IN TRANSLATIONAL ANIMAL NUTRITION
… as the omega-3 polyunsaturated fatty acids (n-3 PUFA) and citrus pectins (CPn) are reported to beneficially affect the host intestinal immunity. However so far, the biological pathways modulated by these nutrients in intestinal inflammation at the level of intestinal epithelial layer (IEL) …
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The effect of apolipoprotein E (APOE) genotype and long chain omega 3 fatty acids on body weight and inflammation
… (M1) phenotype. Long chain (LC) n-3 PUFA, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), exert various beneficial effects on inflammatory and metabolic parameters in relation to obesity. The apolipoprotein Epsilon 4 (APOE4) genotype is associated with a pro-inflammatory …
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The effects of feed supplemented with omega-3 polyunsaturated fatty acids on cultured abalone
… omega-3 polyunsaturated fatty acids (LC n-3 PUFA) are associated with a broad range of health benefits including reducing the risk of cardiovascular diseases, arthritis and certain cancers. In addition, they have also been found to play a role in reducing the risk of Alzheimer’s disease, …
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An examination of the bioactive lipids involved in skin cell inflammation and in response to ultraviolet radiation. Effect of n-3 polyunsaturated fatty acid supplementation on red blood cell and human dermal fatty acid and production of eicosanoids by HaCaT keratinocytes and 46BR.1N fibroblasts following exposure to UVR.
… Omega-3 polyunsaturated fatty acids (n-3 PUFA) are considered anti- inflammatory and could reduce the damage caused by overexposure to UVR. Although, n-3 PUFA have been considered as photoprotective agents, their exact mechanisms of action is not completely understood. The aim of the work …
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How Diet Influences Breast Cancer Risk: Analysis of Tissue Fat, Nutrients, and a Dietary Pattern among High-Risk Women
… consumed ~10 times more n-6 polyunsaturated (PUFA) than n-3 PUFA. Compared to women without atypia, those with atypia had significantly lower n-3 PUFA in their red blood cells and circulating phospholipids, as well as lower total n-3:n-6 PUFA ratios in lipid compartments reflecting recent and …
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Modulation of protein expression in Mycobacterium tuberculosis-stimulated TB- IRIS patient-derived PBMCs by omega n-3 polyunsaturated fatty acids
… for TB-IRIS. N-3 polyunsaturated fatty acids (PUFA) have safely and successfully been used in the treatment of other inflammatory diseases, and we hypothesized that they will have beneficial anti-inflammatory effects on TB-IRIS patient-derived immune cells. To investigate this hypothesis, we …
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Omega-3 polyunsaturated fatty acids utilization in growing pigs fed flaxseed containing diets
… 18:3n-3 and the sum of all n-3 polyunsaturated (PUFA; 95 vs. 110%), AC of 18:3n-3 to n-3 HUFA (19 vs. 22%), and oxidation of 18:3n-3 (7.0 vs. 5.6%); these parameters were influenced by dietary 18:3n-3 level. Pigs fed low dietary 18:3n-3 (0.8 g/kg) yielded both higher RE and AC of 18:3n-3 to n-3 …
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The Effects of Feeding Growing Female Rats Different Sources of Omega-3 Polyunsaturated Fatty Acids on Lipogenic Gene Expression and Lipid Metabolism in Liver and Adipose Tissues
Omega-3 polyunsaturated fatty acid (n-3 PUFA) consumption has increased through diet and supplementation due to reports of health benefits. The objective of this study was to determine whether different n-3 PUFA sources play a role in lipid metabolism by altering lipogenic gene expression, serum …
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Unravelling the anti-inflammatory mechanisms of dietary fatty acids
Polyunsaturated fatty acids (PUFA) have been shown to modulate immune responses and have therapeutic effects in inflammatory disorders. The specific mechanisms of their actions have yet to be defined. The objective of this work was to elucidate such mechanisms. Macrophages are a key component of …
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OMICS APPROACHES FOR OMEGA-6/OMEGA-3 POLYUNSATURATED FATTY ACID RATIO IN PIGS
… (n-6)/omega-3 (n-3) polyunsaturated fatty acid (PUFA) ratio, on porcine meat quality and the integration of OMICS technologies such as genomics, transcriptomics, and proteomics. With the aim of understanding the association between n-6/n-3 PUFA ratios, porcine transcriptome expression, and …
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Polyunsaturated Fatty Acids and the Epidermal Growth Factor Receptor/ Mitogen- Activated Protein Kinase Signal Transduction Cascade in Mammary Cancer
… the diagnosis or follow-up treatment of disease. PUFA have been reported to influence breast cancer risk in humans, and may modulate the EGFR/MAPK pathway through a variety of mechanisms. Dietary PUFA n-6-to-n-3 ratio in cats was reflected in mammary adipose tissue and resulted in altered active …
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Salmon in Pregnancy Study (SIPS): the effects of increased oily fish consumption on maternal nutrient intake, fatty acid status and immunity
… long chain (LC) n-3 polyunsaturated fatty acids (PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), as well as vitamin D and antioxidants (selenium). Fish oil provides EPA and DHA and fish oil supplementation during pregnancy alters offspring immunity in a way that would be …
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Safety of n-3 PUFAs during pregnancy and effects on the metabolic phenotype of the offspring
… to the fetus. As omega-3 fatty acids (n-3 PUFAs) are insulin sensitising and antiinflammatory they may counteract this effect. Thus, supplementing n-3 PUFAs in overweight and obese pregnancy might improve metabolism and body composition of the children. In addition, supplementing oxidised …
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Salmon In Pregnancy Study (SIPS): the effects of increased oily fish intake during pregnancy on maternal and cord blood fatty acid composition, cord blood immunity and atopy outcomes in infants at 6 months of age
… rich in n-6 polyunsaturated fatty acids (PUFAs) and relatively deficient in n-3 PUFAs. These dietary changes are believed to promote a pro-sensitisation, pro-allergic and pro-inflammatory environment. Exposure to such an environment during pregnancy and in the very early life period is …
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Immunomodulation by dietary lipids: soybean oil, menhaden fish oil, chicken fat, and hydrogenated soybean oil in Japanese quail (Coturnix coturnix japonica) and Bobwhite quail (Colinus virginianus)
… fatty acids were polyunsaturated fatty acids (PUFA), was rich in linoleic acid (LA 18:2 n-6), alpha-linolenic acid (ALA 18:3 n-3) and low in saturated fatty acid (SFA). The FO diet which contained about 50% PUFA, had only 40% n-6 fatty acids and 8% n-3 PUFA. The trans fatty acid isomers and …
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