Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"myosin forces"”.
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Structual Visualization of Cytoskeletal Force Tranduction
… environments. This enables contractile forces generated by myosin motors to mediate transduction of mechanical cues into biochemical signaling pathways by unclear mechanisms. In this thesis, I show that myosin forces elicit conformational transitions in actin filaments (F-actin) that …
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A Platform for Analyzing Force Sensitivity and Multivalency in Actin Networks
… and combining them with photo-micropatterning of myosin motor proteins to produce an in vitro reconstitution platform for examining how force impacts the behavior of ABPs within multi-filament assemblies. Our system enables monitoring dozens of actin networks with varying architectures …
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Structural Mechanisms of F-actin Mechanochemical Regulation and Flexible Network Assembly
… by both biochemical processes and mechanical forces. The mechanisms mediating this interplay remain unclear at the protein structural level. Newly polymerized F-actin hydrolyzes bound ATP to produce metastable ADP-Pi–F-actin, which persists for minutes before phosphate release to yield …