Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"myocarditis"”.
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The Rationale, Design and Implementation of the African Cardiomyopathy and Myocarditis Registry
… Africa. Method. The African Cardiomyopathy and Myocarditis Registry Program (IMHOTEP) is a pan-African multi-centre, hospital-based cohort study. It aims to describe the clinical characteristics, aetiology, genetics, management and outcome of cardiomyopathies in children and adults. Index …
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Acute endomyocardial disease in infants and children : the relationship between acute myocarditis and endocardial fibroelastosis
This prospective study of acute myocarditis (AM) and endocardial fibroelastosis (EFE) was prompted by their common occurrence in infants and children in Cape Town, and by the persisting controversy regarding the possible relationship of these two conditions to each other, and to idiopathic, …
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Investigating Clozapine-Induced Myocarditis in Stem Cell-Derived Cardiomyocytes from Treatment-Resistant Schizophrenia Patients: A Pharmacoepigenomic Approach
… due to the risk of severe side effects such as myocarditis (cardiac inflammation). This study explores whether epigenetic regulation may predispose individuals to clozapine-induced myocarditis, aiming to uncover biomarkers that can predict risk of this adverse effect and thus improve clinical …
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Pathological and genetic analysis of host susceptibility to cardiovirulent coxsackievirus B3 infection in mice
Nearly fifty percent of North American myocarditis cases are associated to coxsackievirus group B, type 3 (CVB3) infection. CVB3 infection of mice provides a useful model to study pathogenic mechanism of myocarditis. The objective of this study is to test the hypothesis that susceptibility, during …
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Cardiology Implications of ED COVID-19 Patients in an Underserved Rural Health Care Environment
… cardiac complications (e.g., STEMI, NSTEMI, myocarditis, pericarditis, AF) specifically among underserved communities. Acute STEMI and NSTEMI are cardiac conditions associated with ruptured atherosclerotic plaque leading to significant myocardial injury. AF, the most common arrhythmia leading …
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Arrhythmogenic mechanisms of acute cardiac infection
… sudden cardiac death in young adults caused by myocarditis. Viruses represent the main cause of myocarditis, with adenovirus being a leading pathogen. However, it is not understood how adenoviruses cause sudden cardiac arrest. Myocarditis is defined by two phases, acute and chronic. The acute …
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Control of inflammation, helper T cell responses and regulatory T cell function by Bcl6
… severe Th2-type inflammatory disease including myocarditis and pulmonary vasculitis, suggesting a potential role for Bcl6 in Treg cell function. Bcl6-deficient Treg cells are competent in controlling Th1 responses, but fail to control Th2 inflammation in an airway allergen model. Importantly, …
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Comparative and Functional Genomic Studies of Histophilus somni (Haemophilus somnus)
… H. somni can cause diseases such as pneumonia, myocarditis, abortion, arthritis, and meningo-encephalitis. Previously, several virulence factors/mechanisms had been identified in H. somni of which the phase-variable lipooligosaccharide, induction of host cell apoptosis, intraphagocytic survival, …
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The inactivation of Coxsackievirus B5 with monochloramine for safe global water
… human illnesses including diarrheal diseases and myocarditis. Inactivation of water-borne pathogens has been achieved using disinfectants such as hypochlorous acid or free chlorine. However, Coxsackievirus serotype B5 has demonstrated unique resistance to free chlorine disinfection compared to …
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Towards Novel Methods of Mutagenesis for Histophilus somni
… an etiologic agent of shipping fever pneumonia, myocarditis, and other systemic diseases in bovines, although nonpathogenic commensal strains also exist. Virulence factors that have been identified in H. somni include biofilm formation, lipooligosaccharide phase variation, immunoglobulin binding …
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Cardiovascular magnetic resonance and right ventricular angiography in assessment of right ventricular volumes, function and wall motion abnormalities in arrhythmogenic right ventricular cardiomyopathy: a comparative study
… ARVC registry and the African Cardiomyopathy and Myocarditis Registry Program (IMHOTEP) that have both CMR and RVA data. RV end-systolic and diastolic volumes, RV ejection fractions and the presence of absence of structural abnormalities derived from RVA and CMR are compared. Sensitivity of CMR …
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A influencia da cepa e da reinfecçãoTrypanosom a cruzi para o tabelecimento da forma crônica sintomática da doença de Chagas
… disease, Trypanosoma cruzi, cardiac damage, myocarditis, reinfection, reinfections e strain”. Crit rios de inclusão: artigos originais, idiomas inglês, português ou espanhol, referentes ao tema e publicados entre 2001 e 2014. Após a pesquisa e a pré-seleção foram obtidos 14 artigos. Após …
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Examination of type I IFN mediated regulation of the post-transcriptional antiviral response
… antiviral effect during the acute phase of viral myocarditis caused by Coxsackievirus B3 infection. Taken altogether, the work described in this thesis provides further evidence for the importance of post-transcriptional regulation exerted by IFN-α/β during a virus infection.
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Host Factors That Influence Coxsackievirus B3 Replication and Pathogenensis
… mouth disease, hemorrhagic conjunctivitis, and myocarditis. The virus predominantly infects infants and young children and accounts for 11% of the fatality rate in neonates. Despite CV’s impact on human health, there are no treatments or vaccines for CV infections. Using a mouse model to study a …
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Myocardial intermediary metabolism: with special reference to the isolated, contracting, perfused rat heart
Studies of myocardial metabolism In vivo have been considerably advanced by the introduction of coronary sinus catheterization. By determining the coronary arterio-venous differences of various substrates, Sing and other workers (Goodale, Olson) have been able to describe the overall picture of …
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Imaging Post-Infarct Myocardial Inflammation with ⁶⁸Ga-DOTATATE PET/MRI and insights into COVID-19 associated myocardial injury
… infection, with varied aetiologies ranging from myocarditis to endothelial dysfunction, micro-embolic phenomena and acute coronary syndromes. While persistent cardiac symptoms in patients with post-acute COVID-19 syndrome (PACS) are also common, the underlying cause is less well understood. A …
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Untersuchung der Typ I Interferon-Signaltransduktion in HPV-Onkogen immortalisierten Keratinozyten
… Mit Hilfe der Indikatorviren Encephalo-Myocarditis-Virus (EMCV) und Vesikulo-Stomatitis-Virus (VSV) konnte die biologische Aktivität der konstitutiv exprimierten Interferone gezeigt und ein Zusammenhang zwischen mangelnder IFN--Expression und Verlust der Protektion gegenüber VSV erklärt …
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The utility of the 1994 versus the revised 2010 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Task Force diagnostic criteria for identifying mutation-positive probands with ARVC
… in the IMHOTEP (The African Cardiomyopathy and Myocarditis Registry Program) study with the aim of identifying diagnostic changes that may have clinical impact. Method: 162 participants with the suspicion of ARVC were referred between May 2003 and May 2018 to our ARVC registry. 150 cases were …
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Investigating viral subversion of intercellular communication
… including acute respiratory disease and viral myocarditis. Gap junctions, which are formed by connexin proteins, directly couple the cytoplasms of apposed cells enabling immunological, metabolic, and electrical intercellular communication. The gap junction protein connexin43 (Cx43; gene name – …
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