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Showing 1 to 20 of 65 for “"myo-inositol"”.
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Regulating Inositol Biosynthesis in Plants: Myo-Inositol Phosphate Synthase and Myo-Inositol Monophosphatase
Inositol is important for normal growth and development in plants. The regulation of the inositol biosynthetic enzymes, <I>myo</I>-inositol phosphate synthase (MIPS) and <I>myo</I>-inositol monophosphatase (IMP) was investigated. The specific aims of this research were (1) to develop a tool to …
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Biochemical Studies on Myo-Inositol
Made available in DSpace on 2014-12-05T19:37:02Z (GMT). No. of bitstreams: 1 5900548.pdf: 3497709 bytes, checksum: 6bef2131bd20b0781a92d9936db7fbf0 (MD5) Previous issue date: 1958
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Synthesis, crystallography and biological activity of myo-inositol phosphates
The antioxidant property of myo-inositol hexakisphosphate is important in the prevention of hydroxyl radical formation which may allow it to act as a 'safe' carrier of iron within the cell. Here, the hypothesis that the recently discovered natural product, myo-inositol 1,2,3-trisphosphate …
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Towards biosensor-assisted directed evolution of myo-inositol oxygenase
… for this work was the directed evolution of myo-inositol oxygenase (MIOX), the enzyme that catalyzed the penultimate, rate-limiting step in the metabolic production of glucarate from glucose in E. coli. Here, we develop a biosensor that recognizes glucuronate, the direct product of MIOX, and …
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Molecular Characterization of Two myo-Inositol Oxygenases in Arabidopsis thaliana
… stresses. One stress-responsive system involves myo-inositol (Ins). Ins is a precursor for cell wall components, inositol trisphosphate (Ins(1,4,5)P3) and phosphatidylinositol phosphate signaling molecules, and an alternate ascorbic acid (AsA) synthesis pathway. The enzyme, myo-inositol oxygenase …
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Identification and Functional Role of Myo-Inositol Polyphosphate 5-Phosphatase Protein Complexes
… termination through second messenger hydrolysis. Myo-inositol polyphosphate 5-phosphatases (5PTases) (EC 3.1.3.56) have unique signal terminating abilities toward the second messenger inositol trisphosphate (Ins (1,4,5)P3, InsP3). In Arabidopsis thaliana there are 15 members of the 5PTase family, …
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Nutritional and environmental factors in human spina bifida - An emphasis on myo-inositol.
Contains fulltext : nutranenf.pdf (Publisher’s version ) (Open Access)
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Molecular characterization of XvlNO1, a myo-inositol 1-phosphate synthase gene from Xerophyta viscosa
Myo-inositol I-phosphate synthase (INO 1) catalyses the conversion of glucose-6-phosphate to myo-inositol I-phosphate, which is subsequently dephosphorylated to myo-inositol. Myo-inositol is a precursor for a number of important metabolites that include membrane components, storage molecules, …
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Isolation and Characterization of D-Myo-Inositol-3-Phosphate Synthase Gene Family Members in Soybean
… isolate genes encoding isoforms of the enzyme D-myo-inositol 3-phosphate synthase (MIPS, E.C. 5.5.1.4) from soybean and to characterize their expression, especially with respect to their involvement in phytic acid biosynthesis. A MIPS-homologous cDNA, designated GmMIPS1, was isolated via PCR …
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Isolation and Characterization of Soybean Genes Involved in Phytic Acid Metabolism: Phytase and 1-L-myo-Inositol-1-Phosphate Synthase
… to control non-transformed cultures. A soybean L-myo-insoitol-1-phosphate synthase (MIPS) cDNA was isolated from total RNA from developing seeds. The protein encoded by the soybean MIPS cDNA showed 87-91% homology to MIPS protein sequences from other plant species. RNA blot analysis of staged …
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X-ray Crystallography of Inositol Dehydrogenase Enzymes
… and iolG2. They have been putatively assigned as myo-inositol dehydrogenases by sequence comparison. The enzyme catalyzes the reversible conversion of myo-inositol to scyllo-inosose and the concurrent reduction of NAD+ to NADH. iolG1 was subsequently determined to be a myo-inositol dehydrogenase …
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Identification and Characterization of Late Pathway Enzymes in Phytic Acid Biosynthesis in Glycine max
Phytic acid, also known as myo-inositol hexakisphosphate or Ins(1,2,3,4,5,6)P6, is the major storage form of phosphorus in plant seeds. Phytic acid is poorly digested by non-ruminant animals such as swine and poultry, and it chelates mineral cations including calcium, iron, zinc, and potassium, …
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Biosensor-based strategies for improving pathway production in Escherichia coli
… to be limited by the two downstream enzymes myo-inositol-1-phosphate synthase (MIPS) and myo-inositol oxygenase (MIOX). This work develops and deploys a biosensor that recognizes a pathway intermediate in order to overcome both limitations. A biosensor for myo-inositol (MI) was developed …
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Molecular Characterization of Inositol Monophosphatase Like Enzymes in Arabidopsis thaliana
myo-Inositol synthesis and catabolism are crucial in many multicellular eukaryotes for production of phosphatidylinositol and inositol phosphate signaling molecules. myo-inositol monophosphatase (IMP) is a major enzyme required for the synthesis of myo-inositol and breakdown of inositol …
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Retrobiosynthesis of D-glucaric acid in a metabolically engineered strain of Escherichia coli
… is the second recombinant step, catalyzed by myo-inositol oxygenase (MIOX), whose activity is strongly influenced by the concentration of the myo-inositol substrate. To increase the effective concentration of myo-inositol, synthetic scaffold devices were built from protein-protein interaction …
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