Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"myeloproliferative disease"”.
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Evolução da leucemia mielóide crônica frente à terapia com inibidores de tirosina cinase.
The Chronic Myeloid Leukemia (CML ) is a myeloproliferative disease by developing skilled clone of hematopoietic cells carrying Philadelfia chromoso me ( Ph ) , deriving the respective translocation between the long arms of chromosomes 9 and 22 , t( 9:22) (q34;11 ). As a result of this molecular …
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The Interplay of Signal Transduction and Membrane Traffic of the Macrophage Colony Stimulating Factor Receptor (MCSFR) Controls Macrophage Growth
… pathway is associated with numerous inflammatory diseases as well as myelogenous leukemias. Clearance of RTKs from the plasma membrane is an important mechanism for regulating the signal amplitude, however, the exact mechanisms remain elusive. To better define these mechanisms, we characterized …
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Oncogenic roles of RAS in acute myeloid leukemia cooperated with Mll-AF9.
… G12V transgenic mice without detectable other diseases. We assayed Vav-tTA -driven luciferase expression in hematopoietic cells including bone marrow-derived mast cells (BMMC) and CD34 positive hematopoietic progenitor cells (HPC) as well as myeloid and lymphoid lineages by live mouse imaging …
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Heterogeneous Nuclear Ribonucleoprotein K (Hnrnp K) Overexpression and Its Interaction With Runx1 Rna In Acute Myeloid Leukemia
… its putative oncogenic capacity in myeloid disease, we overexpressed hnRNP K in murine hematopoietic stem and progenitor cells isolated from fetal liver cells (FLCs). We revealed that hnRNP K-overexpression alters self-renewal capacity and differentiation potential of these cells <em>in …