Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"myelin protein zero"”.
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Crystallographic, Molecular Dynamics, And Enzymatic Studies Of Multi-Drug Resistant Hiv-1 Protease And Implications For Structure Based Drug Design (project 1); Crystallographic Studies Of Human Myelin Protein Zero (project 2)
… <p>The extracellular domain of human myelin protein zero fused with maltose binding protein is crystallized to investigate the molecular mechanism of Charcot-Marie-Tooth disease subtype 1B. The based on the wild type structure of the extracellular domain of human myelin protein zero, …
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Charcot-Marie-Tooth-Neuropathie Typ 2 : neue Myelinprotein-P0-Punktmutationen und Haplotypenanalyse in europäischen Familien
… and nerve pathology, CMT is subdivided in demyelinating CMT1 and axonal CMT2. Causative gene mutations can be identified in about 80-90% of CMT1 patients while no major CMT2 gene has been identified so far. In the present study, 49 CMT2 patients were tested for mutations in the myelin protein …
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Entwicklung von Merkelzellen in der Haut von P0-defizienten Mäusen
… als Mechanorezeptor der Haut wird von einer myelinisierten langsam adaptierenden Afferenz (Aß) innerviert. Deshalb wurde in der vorliegenden Arbeit als sekundärer Indikator für die distale Innervation in P0-defizienten Mäusen, ein Tiermodell der hereditären motorisch-sensorischen …
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Elevated Cochlear Adenosine Causes Hearing Loss Via Adora2B Signaling
… observed nerve fiber density loss and aberrant myelin compaction. More importantly, we found that treatment of FDA-approved drug, polyethylene glycol-ADA (PEG-ADA), lowered cochlear adenosine levels and improved functional and structural phenotypes of <em>Ada<sup>-/-</sup></em> mice. In addition …