Global ETD Search
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Showing 1 to 8 of 8 for “"mycosis fungoides"”.
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Exploring the genetic landscape in cutaneous T-cell lymphoma with short- and long-read sequencing
… of samples from the most common CTCL subtype, mycosis fungoides, revealed a low tumor cell fraction in bulk skin biopsies. To tackle this issue, an approach for enrichment of malignant cells was applied. This allowed a more confident calling of somatic variants, especially for copy-number …
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Διερεύνηση των καρκινικών Τ κυττάρων στο δερματικό Τ κυτταρικό λέμφωμα
Η Σπογγοειδής Μυκητίαση (Mycosis Fungoides, MF), είναι ένα δερματικό λέμφωμα που χαρακτηρίζεται από τον ανεξέλεγκτο πολλαπλασιασμό καρκινικών Τ λεμφοκυττάρων. Στα αρχικά της στάδια, εμφανίζεται με τη μορφή κηλίδων και λεπτών πλακών στο δέρμα και περίπου το ένα τρίτο των ασθενών αργότερα αναπτύσσουν …
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A candidate gene based investigation of aberrant DNA methylation in the pathogenesis of primary cutaneous T-cell lymphoma
… malignancy of mature skin-homing T-cells. Mycosis fungoides (MF) is an indo¬lent subtype of CTCL whilst Sezary syndrome (SS) is an aggressive leukaemic variant characterised by the presence of malignant Sezary cells in the periph¬eral blood. A role for epigenetic mechanisms in the …
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Identification of differentially expressed genes in AHI-1-mediated leukemic transformation in cutaneous t-cell lymphoma
… a common leukemic variant of the human CTCL mycosis fungoides. Aberrant expression of AHI-1 mRNA and protein has been found in CD4⁺CD7⁻ leukemic Sezary cells from patients with Sezary syndrome. Moreover, stable suppression of AHI-1 using retroviral-mediated RNA interference in Hut 78 cells …
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Serologische Identifizierung von Tumorantigenen des kutanen T-Zell Lymphoms mit Fokus auf Plasmamembranproteine
… T-Zell Lymphome (CTCL), Sézary Syndrom (SzS) und Mycosis fungoides (MF), sind. Zu ihrer Identifizierung wurde zunächst über differentielle Zentrifugation ein Oberflächenpräparat der CTCL-Zelllinie HuT78 hergestellt. Es diente als Antigengemisch für die Immunisierung von Kaninchen. Die gewonnenen …
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Expression of Follicular Helper T-cell Markers in Primary Cutaneous T-cell Lymphoma
… T-cell lymphoma were examined: 25 patients with mycosis fungoides (MF), 9 with lymphomatoid papulosis, 8 with anaplastic large cell lymphoma, 4 with subcutaneous panniculitis-like T-cell lymphoma, 2 with peripheral T-cell lymphoma, and 1 with NK/T-cell lymphoma. Chart review was performed to …
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Investigating lesions of Langerhans cells and their role in Lymphoproliferative diseases
… (B-CLH), lymphomatoid papulosis (LyP) and mycosis fungoides (MF) are reported. In two female cases, the LCs were polyclonal providing some reassurance that such lesions are reactive in nature and should not be regarded as potential second neoplasms. In a more expanded study a wide variety …
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Erweiterung eines diagnostischen Verfahrens zur Differenzierung entzündlicher Dermatosen mittels Immunphänotypisierung dendritischer Zellen der Epidermis
… atopischer Diathese (n=14); Lichen ruber (n=6); Mycosis fungoides (n=10) und Nummuläres Ekzem (n=8). Es konnte gezeigt werden, dass der prozentuale Anteil epidermaler dendritischer Zellen in Abhängigkeit von der Diagnose variiert und dass die bei allen entzündlichen Dermatosen nachweisbare …