Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 3372 for “"mutant"”.
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Mutant Store
Mutant Store es una cadena de suplementos deportivos que pertenece a la organización Mazeta S.A.C, recientemente constituida para la apertura de tiendas Mutant Store. Esta cadena se lanza debido a la proyección del incremento en la venta de suplementos deportivos y la búsqueda de un cuerpo más sano …
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Targeting mutant p53 in cSCCs
… of the main risk factors for cSCC development. Mutant p53 proteins can lose wt-p53 functions, have dominant-negative effects against wt-p53 and acquire gain of function (GOF) activities. Mutant p53 GOF activity is induced by the accumulation of mutant p53 in tumour cells. Mutant p53 accumulation …
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Campaña de lanzamiento de Mutant Store
… para la tienda virtual y las tiendas físicas de Mutant Store, donde se venderá exclusivamente los suplementos deportivos de la marca canadiense Mutant. La campaña tiene como objetivo lograr un 20% de participación de mercado en los canales digitales y 2% de participación en los canales offline. …
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Campaña de lanzamiento de Mutant Store
… elaboración de una campaña de lanzamiento para "Mutant Store," una tienda de marca única que ofrecerá exclusivamente los productos "Mutant" en el mercado a partir de noviembre. El objetivo principal de esta propuesta es lograr una visibilidad y consideración entre el público objetivo, con el fin …
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An investigation of mutant p53 function.
… form of the full-length p53 protein. This mutant protein exhibits a loss of tumour suppressive activity, dominant-negative activity to inactivate functional p53 and gain-of-function properties to drive tumour progression and metastasis. Investigation into mutant p53-mediated oncogenic …
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BEHAVIOURAL ANALYSIS OF ZEBRAFISH RELAXIN-3A MUTANT
… was generated in the <i>rln3a</i> locus. Mutants showed mild changes in body weight, anxiety and visuomotor response compared to wildtype siblings. A single nucleotide polymorphism (c.158C>T) was found, resulting in a non-synonymous mutation in the coding sequence of the C-peptide. Fish …
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Functionality of mutant p53 in early tumorigenesis
… gain of function (GOF) activities. However, mutant p53 is more commonly studied following loss-of-heterozygosity (p53mut/-) which is thought to promote tumorigenesis. The functionality of mutant-p53 in early tumorigenesis (p53mut/+) has been underexplored but it may uncover how the mutation …
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Synaptic plasticity in the MyosinVa mutant mouse
… the hippocanmpus from MyosinVa dominant negative mutant flailer mouse using field potential recordings. Flailer mice showed no impairment of LTP or NMDAR-dependent LTD, consistent with the findings of the study on dilute-lethal. In addition, MyosinVa has been implicated in the transport of an …
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MUTANT P53 AS A THERAPEUTIC TARGET IN CANCER
… canonical chemotherapies, putting patients with mutant p53 at a greater disadvantage regarding clinical outcomes. Our group has previously characterized the P47S hypomorphic variant as a defective tumor suppressor associated with increased cancer risk in African descent individuals, in part due …
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Campaña de lanzamiento para la marca: Mutant Store
Mutant Store es una tienda especializada de suplementos deportivos, la cual estará entrando en el mercado en el mes de noviembre del 2023 con 3 locales en los distritos de Miraflores y Surco. Dicha tienda venderá, de manera exclusiva, productos de la marca Mutant, la cual es una marca extranjera y …
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A phosphorus mutant of Arabidopsis thaliana / Bei Dong.
In this study an EMS-mutated Arabidopsis mutant pho2, which accumulates Pi in leaves, was used to study Pi uptake and transport by comparing it to wild-type seedlings. The study aimed to define the physiological lesions in pho2 mutant and to obtain evidence regarding the function of the PHO2 gene …
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Transcription Following Mutant and Wild Type Phage Infections
Made available in DSpace on 2014-12-09T22:04:13Z (GMT). No. of bitstreams: 1 6607764.pdf: 4484955 bytes, checksum: dc893c703f3781ee3b13a3da023a24de (MD5) Previous issue date: 1966
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The crystal structure of a mutant nitrile hydratase
Nitrile hydratases can be used as industrial biocatalysts. They catalyze the conversion of nitriles to their corresponding amides. These industrial biocatalysts have recently gained attention due to the economic production of industrial commodities such as acrylamide and nicotinamide (Thomas et …
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Cooperative Genomic Events Driving Mutant TP53-Driven DCIS Progression
… early in DCIS, suggesting a critical role for mutant <em>TP53</em> in driving disease progression. Using a somatic mouse model of <em>p53<sup>R245W</sup></em> induced breast cancer (equivalent to the <em>TP53<sup>R248W</sup></em> hotspot mutation in humans), we identified DCIS lesions. Through …
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Characterization of xtcl mutant with reduced cuticular wax accumulation
… protective roles. The isolation of wax deficient mutants from Arabidopsis and other plants resulted in identification and isolation of genes required for wax deposition, and broadened our knowledge of this process in plants. To identify additional components involved in cuticular wax production, I …
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Biophysical Characterization Of A Proline Mutant Of Neural Cadherin
Cadherins are calcium dependent glycoproteins whose homophilic interactions mediate cell-cell adhesion in solid tissues. They are comprised of an extracellular region, a transmembrane region and a cytoplasmic region. The extracellular region plays a critical role in cadherin-mediated cell adhesion, …
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Erythritol metabolism in a dome mutant of Schizophyllum commune
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Analyses of a genic male-sterile mutant in soybean
<p>A new genic male-sterile mutant in soybean was characterized genetically, developmentally, and molecularly. This mutant is controlled by a single recessive gene, which is not allelic to six previously identified soybean genic male-sterile mutants: ms1, ms2, ms3, ms4, ms5, or ms6. No linkage was …
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