Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"musculoskeletal disease"”.
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An investigation into the risk factors of musculoskeletal diseases and the association between chronic diseases of lifestyle in an under-resourced area of the Cape Town Metropole
… A recent shift in the global burden of disease from communicable to noncommunicable has shown that a third of the global burden of disease is attributable to noncommunicable disease, with the heaviest burden affecting poor communities in urban areas. Musculoskeletal disease (MSD) is the …
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IMPLANT MATERIAL FUNCTIONALIZATION TO ENHANCE BIOACTIVITY IN ORTHOPAEDICS
Musculoskeletal disease is one of the leading causes of long term physical disability. One of the key challenges in bone healing and regeneration is the engineering of an implant that incorporates osseointegration to meet the metabolic demands of recovery. Although implants are typically expected …
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Evaluation of allogeneic bone marrow-derived mesenchymal stem cells for use in equine joints: in vitro to preclinical evaluation
Joint disease is prominent in the equine population and horses provide a highly translational model for human joint disease. Mesenchymal stem cells (MSCs) have been investigated as a treatment of musculoskeletal disease in the horse with autologous MSCs showing promise as a treatment of desmitis, …
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Electromechanical systems to enhance the usability and diagnostic capabilities of ultrasound imaging
… Common uses include fetal, vascular, and musculoskeletal imaging, as well as biopsy needle insertion guidance. With 165 million ultrasound exams conducted in the United States annually, and an annual US market of $1.3 billion, improvements to the usability and diagnostic capabilities of …
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Tissue Engineering Cartilage with a Composite Electrospun and Hydrogel Scaffold
Osteoarthritis is the most prevalent musculoskeletal disease in humans, severely reducing the standard of living of millions of people. Osteoarthritis is characterized by degeneration and loss of articular cartilage which leads to pain, and loss of joint motility and function. Individuals suffering …
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Prediction of knee loading in native knee and total knee arthroplasty : a forward dynamics computational study
"The goal of this dissertation is to develop a musculoskeletal model and corroborate model predictions to experimentally measured in vivo knee contact forces, in order to study the biomechanical consequences of two different total knee arthroplasty designs. The two main contributions of this …
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Inflammatory and Immune Effects of Intra-Articular Mesenchymal Stem Cells in Horses
… study as a potential treatment of equine joint disease. The goal of the study is to investigate the inflammatory and immune response to intra-articular injection of autologous, genetically modified (bone morphogenetic protein 2) autologous, allogeneic, and xenogeneic bone marrow-derived …
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Exercise & cardiopulmonary physiology in rheumatoid arthritis
… to (1) obtain information on the rheumatic and musculoskeletal disease (RMD) patents’ achieved/preferred exercise principles and awareness, (2) investigate the need to implement and safety, as depicted when a verification phase is added at the cardiopulmonary exercise tolerance test (CPET) in …
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Effectiveness of single and combined treatments on biomechanical and clinical outcomes during walking in healthy individuals and individuals with knee osteoarthritis
… (OA) is considered a common chronic musculoskeletal disease affecting the medial compartment more than the lateral compartment and leading to disability and a reduction in activity level. Lateral wedge insoles (LWI) are a conservative treatment that aims to reduce the knee loading …
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Role of MicroRNAs in Human Skeletal Muscle Tissue Engineering In Vitro
… to study the process of myogenesis, various musculoskeletal disease states, and drugs and therapies for muscle toxicity. We developed a protocol to culture human skeletal muscle bundles in a fibrin hydrogel under static conditions capable of exerting active contractions. Additionally, we …
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Dynamic surface topography and its application to the evaluation of adolescent idiopathic scoliosis
… of the spine is one of the major skeletal diseases in adolescents where in the majority of cases the cause is unknown or idiopathic. The progression of the disease occurs in three dimensions with the spine simultaneously curving towards the arms and rotating as it collapses with the first …
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Pain alleviating effects of mesenchymal stem/stromal cells and derived extracellular vesicles in osteoarthritis
Musculoskeletal disorders pose significant burdens on both individuals and society. Osteoarthritis (OA) is a common form of musculoskeletal disease affecting around a third of the population aged over 60 years old. It is characterised by debilitating joint pain and stiffness that only partially …
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Disability and Return to Work Following Musculoskeletal Injury
Musculoskeletal disorders (MSDs) are injuries, damage or disorders affecting the musculoskeletal system including muscles, ligaments, nerves, tendons, bones or cartilage etc. MSDs are highly prevalent and associated with sickness absence, reduced work efficiency, job changes and earlier …
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Overweight and Obesity in Health Care Workers in Relation to Musculoskeletal Conditions and Weight Loss
<p>Musculoskeletal disorders (MSD) are the most prevalent occupational injuries in nursing home employees. Most of the research and interventions in the past 30 years have focused on teaching and training nursing home staff proper lifting and body mechanics to reduce the risk of injury. The …