Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 13 of 13 for “"muscle protein turnover"”.
-
Essential Amino Acid (EAA) Regulation of Skeletal Muscle Protein Turnover with Age
<p>Skeletal muscle (SM) is vital for both long term health and quality of life. Recent research suggests an increase in catabolic signals with age triggers pathologic conditions, such as sarcopenia. Although results from in vitro studies model how EAA can regulate muscle protein synthesis (MPS), …
-
Skeletal Muscle Protein Turnover During Cancer Cachexia In the Apc<sup>min/+</sup> Mouse
… condition associated with the loss of skeletal muscle and fat mass. Muscle wasting exhibits an imbalance in the rate at which proteins are synthesized and degraded, referred to as protein turnover. Our laboratory has shown the ApcMin/+ mouse, a model of colorectal cancer is an excellent model to …
-
Influence of dietary amino acid adequacy on performance and muscle protein turnover in poults
… studies were designed to investigate changes in muscle composition and protein turnover in response to essential (EAA) and nonessential amino acid (NEAA) supplementation of the low protein diet. Developmental changes in muscle metabolism as well as differences between muscles were also examined. …
-
The Effect of Cancer Cachexia Progression on the Feeding Regulation of Skeletal Muscle Protein Turnover
… is defined as the unintentional loss of skeletal muscle mass with or without fat loss that cannot be reversed by conventional nutritional support. Cachexia occurs in ~20% of cancer patients. More specifically, 50% of lung cancer patients, the most common cancer worldwide, develop cachexia. …
-
The effect of leucine and dileucine ingestion on muscle protein turnover in healthy young men
Skeletal muscle mass and quality, which is determined by day-to-day changes in muscle protein synthesis (MPS) and muscle protein breakdown rates (MPB), are important determinants of physical performance and metabolic health across all age groups. As such, identifying nutritional and exercise …
-
Effects of physical activity levels and nutritional intake on skeletal muscle protein turnover and cellular signaling
Loss of muscle mass is common in many clinical conditions such as cancer, AIDS, burns and paralysis as well as in aging. Decreased muscle mass can contribute to many other complications and co-morbidities related to diseases, trauma and aging including overall weakness, immobility, increased risk …
-
Characterization of estrogen and glucocorticoid receptors, skeletal muscle protein turnover and tissue growth in lambs treated with trenbolone acetate and estradiol
… of the glucocorticoid and E2 receptor, skeletal muscle protein turnover and tissue growth. Twenty-four lambs were utilized. Trenbolone acetate did not ,affect (P>.10) degradation rates in the semitendinosus (ST) and triceps brachii (TB) muscles, the production of cortisol, adrenal weights and …
-
Effect of Severe Burn Injury on Body Composition and Muscle Metabolism in Pediatric Patients
Muscle wasting in burn injury is associated with increased morbidity and mortality. Burn-induced muscle cachexia is partly attributed to lack of physical activity imposed by standard of care. Moreover, evidence supports that muscle tissue is catabolized to provide amino acids necessary for wound …
-
Amino Acid Sensing in Muscle: Role of the lysosome and the effect of protein supplementation on improving amino acid sensitivity in aging muscle
Protein ingestion is a well-studied stimulus for increasing skeletal muscle protein synthesis. Only recently has the mechanism for this phenomenon been elucidated at the cellular level. To this point, most of the mechanistic research into this process has been conducted in human embryonic kidney …
-
Novel drug and exercise therapies to restore metabolic function in children with severe burns
… workload, elevated energy expenditure, altered muscle metabolism, a severe loss in lean body mass, and impaired physical function. This stress response can extend well beyond wound healing, which can negatively impact an individual’s quality of life and their ability to reintegrate into society. …
-
Protein quality and distribution determines anabolic signaling, cellular energetics, and body composition
Building and maintaining muscle is critical to the quality of life for adults and elderly. Physical activity and nutrition are important factors for long-term muscle health. In particular, dietary protein – including protein distribution and quality – are under-appreciated determinants of muscle …
-
Defining the relationship between basal myofibrillar protein synthesis and resting metabolic rate
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms
-
Regulation of Protein Turnover during Hyper-osmotic Stress in Skeletal Muscle
… to examine the effect of hyper-osmotic stress on protein turnover in skeletal muscle tissue using an established in-vitro model. Rat EDL muscles were incubated in either hyper-osmotic (400 ± 10 Osm) or isoosmotic (290 ± 10 Osm) custom-modified media (Gibco). L-[14C]-U-phenylalanine (n=8) and …