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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 46 for “"muscle metabolism"”.
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AMP-activated protein kinase and muscle metabolism
… kinase (AMPK) is a major regulator of skeletal muscle metabolism with relevance to agriculture and human health. During the conversion of muscle to meat, the rate and extent of postmortem metabolism and pH decline largely determine pork quality development. Pigs with the AMPKγ3 R200Q mutation …
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Signaling pathways regulating skeletal muscle metabolism and growth
Skeletal muscle can perceive cellular energy status and substrate availability and demonstrates remarkable plasticity in response to environmental changes. Nonetheless, how skeletal muscle and its resident stem cells (satellite cells; SCs) sense and respond to nutrient flux remains largely …
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Myogenin Modulates Exercise Endurance By Altering Skeletal Muscle Metabolism
… of these MRFs, myogenin (Myog), during embryonic muscle development suggests an equally important role in adult muscle. In this study, we have determined the function of myogenin during adult life using a conditional allele of Myog. In contrast to embryonic development, myogenin is not required …
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Influence of protein nutrition and exercise on muscle metabolism
… can markedly alter the acute response of muscle protein synthesis and, potentially, long-term phenotypic adaptation. Protein nutrition has traditionally been considered in the context of resistance exercise. Endurance exercise followed by protein ingestion increases the synthesis of mixed …
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The Role of Angiotensin II in Skeletal Muscle Metabolism
… recently been investigated for its effects on metabolism and diabetes. Since skeletal muscle is one of the most metabolically active tissues, this study investigates the effects of angiotensin II specifically on skeletal muscle. In this study, L6 skeletal muscle cells were treated with …
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Whole-Body Metabolic Flexibility is Discordant with Skeletal Muscle Metabolism
… in response to substrate availability. Skeletal muscle (SkM) is a regulator of metabolic flexibility as it is the primary tissue responsible for post-prandial substrate handling, and metabolic inflexibility can be seen in the SkM of individuals with metabolic disease. As Western style diets are …
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Effect of Severe Burn Injury on Body Composition and Muscle Metabolism in Pediatric Patients
Muscle wasting in burn injury is associated with increased morbidity and mortality. Burn-induced muscle cachexia is partly attributed to lack of physical activity imposed by standard of care. Moreover, evidence supports that muscle tissue is catabolized to provide amino acids necessary for wound …
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Elucidating Functional Roles For Myogenin In Adult Skeletal Muscle Metabolism, Exercise Capacity, and Regeneration
… and MyoD are critical for embryonic skeletal muscle development. Myogenin is necessary for the terminal differentiation of myoblasts into myofibers during embryogenesis, but little is known about the roles played by myogenin in adult skeletal muscle function and metabolism. Furthermore, while …
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The role of Toll-like Receptor 4 in the Modulation in Skeletal Muscle Metabolism
… demonstrated that activation of TLR4 in skeletal muscle results in the preferential oxidation of glucose for ATP production over that of fatty acids. Currently, the exact mechanism(s) for TLR4-induced modulation of metabolism are not known. The purpose of this project was to test the hypothesis …
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The Role of High Saturated Fatty Acid Diets on Skeletal Muscle Metabolism and Inflammation
… if the metabolic adaptive response in skeletal muscle to a single, high fat meal was altered by 5 days of high saturated fat feeding. Twelve college-age, non-obese males were studied and skeletal muscle samples were obtained prior to and concluding the consumption of a high SFA diet. In a subset …
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Influence of biological sex and thyroid hormone on skeletal and cardiac muscle metabolism in heat-stressed pigs
… temperatures caused by climate change. Skeletal muscle, which is the main source of income for the meat industry, is particularly sensitive to HS. Lean tissue accretion declines during HS, in part because of inefficient metabolism and altered metabolic flexibility. The first study examined …
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Effect of Oxygen-Limiting Tidal Conditions on Muscle Metabolism and Structure in the Giant Acorn Barnacle, Balanus nubilus
<p>Crustacean muscle fibers are some of the largest cells in the animal kingdom, with fiber diameters in the giant acorn barnacle (<em>Balanus nubilus</em>) exceeding 3 mm. Sessile animals with extreme muscle sizes and that live in the hypoxia-inducing intertidal zone – like <em>B. nubilus</em> – …
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The effect of environmental temperature on exercise metabolism
… of exercise in different ambient temperatures on muscle metabolism, in particular carbohydrate metabolism, has produced conflicting results. The definitive mechanisms whereby exercise in different environmental conditions affects muscle metabolism have yet to be determined. The studies reported in …
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Energy metabolism in skeletal muscle: mechanistic insights into mitochondrial function and growth
Skeletal muscle metabolism is critical to understanding the efficiency of muscle growth for the global meat industry. As such, there are many contributing factors that can influence muscle growth yet there are still basic molecular mechanisms that remain unexplored. Specifically, the involvement of …
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Acute and chronic heat stress alters the metabolic profile of skeletal muscle in growing swine
… lean tissue accretion. Perturbations in skeletal muscle metabolism may participate in this defect. The study objectives were to examine the cellular bioenergetic profile in skeletal muscle of piglets subjected to thermal stress in utero and/or during postnatal life. To accomplish this, 96 …
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The effects of tributyrin and butyrate on equine skeletal muscle
… for supplements that can improve performance and muscle recovery. Tributyrin and butyrate affect satellite cells and oxidative metabolism in other species. To assess the effects of tributyrin on equine muscle repair, Thoroughbred horses were supplemented tributyrin, and a submaximal exercise test …
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Skeletal muscle structure and metabolism in chronic heart failure
… exercise intolerance. Maladaptations in skeletal muscle appear to be a likely reason for the limited exercise tolerance. In study I, exercise tolerance and skeletal muscle metabolism and morphology were examined in 17 CHF patients and eight healthy similarly aged sedentary control subjects. In …
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Modulation of exercise-induced gene expression in human skeletal muscle by exercise intensity, training status and short-term endurance training
… modulation of gene expression in human skeletal muscle under varying physiological conditions, including divergent exercise intensities, untrained and trained muscle, and short-term endurance training. Compared to low intensity isocaloric exercise (400 kcal, 40%VO2peak), a single bout of high …
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Novel drug and exercise therapies to restore metabolic function in children with severe burns
… workload, elevated energy expenditure, altered muscle metabolism, a severe loss in lean body mass, and impaired physical function. This stress response can extend well beyond wound healing, which can negatively impact an individual’s quality of life and their ability to reintegrate into society. …
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Nitrogen Metabolites During Exercise in the Horse
… (NH$\sb3$) levels on fatigue development and muscle metabolism. The horses were exercised on an 11% grade treadmill at 4.4 m/s, carrying 27 kg of lead. Time to fatigue was not (P $>$.05) different between groups. Middle gluteal muscle (im) NH$\sb3$ and lactate increased (P $$.05). Treatment …
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