Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 67 for “"muscle growth"”.
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The Cellular Basis for Skeletal Muscle Growth Retardation (Undernutrition)
Attempts to explain the basis for permanent growth retardations often focus on the cell number/cell size hypothesis. According to this hypothesis, undernutrition produces irreversible effects if and only if it occurs during the time of rapid DNA accretion. If tissue DNA contents are used to …
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Muscle Growth and Development in Intrauterine Growth Restricted Pigs
Intrauterine growth restriction causes impaired growth and development of mammalian fetus, and leads to long-term negative effect on postnatal growth. Among domestic animals, pigs exhibit the most severe naturally occurring IUGR and reduced postnatal muscle growth. The objectives of this research …
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Hypoxia and exercise: novel treatment strategy for muscle growth and weight loss.
La investigación previa en el uso del entrenamiento en hipoxia se ha centrado en las adaptaciones y respuestas fisiológicas derivadas de estos programas en deportes de resistencia y deportes colectivos. Además, en los últimos años ha surgido una aplicación terapéutica del uso de la hipoxia como …
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α7β1 integrin regulation of skeletal muscle growth in response to mechanical loading
… integrin subunit in the regulation of skeletal muscle mass in response to mechanical loading. The purpose of this study was to 1) to utilize an automated computer program (SMASH) to reassess myofiber cross-sectional area in previously collected samples, and 2) to determine the mechanism by which …
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α7β1 integrin regulation of skeletal muscle growth in response to mechanical stimulation
… integrin subunit in the regulation of skeletal muscle mass. The purpose of this dissertation was to 1) use gene expression profiling to reveal potential mechanisms by which the α7BX2 integrin can promote an increase in muscle mass post- eccentric exercise, 2) determine the extent to which the …
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Systems level investigation of the genetic basis of bovine muscle growth and development
Skeletal muscle growth is an economically and biologically important trait for livestock raised for meat production. As such, there is great interest in understanding the underlying genomic architecture influencing muscle growth and development. In spite of this, relatively little is known about …
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The Effect of Protein Blend Supplementation and Resistance Exercise on Skeletal Muscle Growth and Adaptation
… efficacy of a new protein supplement to improve muscle growth and strength when ingested following exercise. The hypothesis is that novel supplementation of mixed dietary proteins (protein “blend”) with different amino acid release profiles will prolong amino acid levels in the blood leading to …
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Regulation of skeletal muscle growth and gene expression by insulin-like growth factors and myostatin
Insulin-like growth factor 2 (IGF2) is a maternally imprinted growth factor that is thought to primarily promote prenatal skeletal muscle growth. A SNP within intron 3 of IGF2 identified as IGF2-intron3-G3072A has a considerable impact on lean yield as a result of increased postnatal IGF2 …
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Does Blood Flow Restriction Applied Post High-Load Exercise Augment Skeletal Muscle Growth Following Eight Weeks of Training?
… exercise has consistently been shown to augment muscle hypertrophy which has been attributed to metabolic accumulation. It remains unknown, however, whether metabolites can augment muscle growth independent of further mechanical tension, specifically when maintained post high-load training. …
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The effects of maternal and postnatal infections with porcine reproductive and respiratory virus on muscle growth and development in piglets
… feed intake, limit weight gain, and decrease muscle growth by directing nutrients away from protein accretion and towards an inflammatory response; however, it is unclear how maternal infection affects offspring skeletal muscle development. Additionally, it is unclear how viral infections …
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Roles of Growth Hormone, Insulin-Like Growth Factor I, and Sh3 and Cysteine Rich Domain 3 in Skeletal Muscle Growth
… 1) to determine the cellular mechanism by which growth hormone (GH) stimulates skeletal muscle growth; 2) to identify the signaling pathways that mediate the different effects of insulin-like growth factor I (IGF-I) on skeletal muscle growth; and 3) to determine the role of a functionally unknown …
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Effects of ractopamine hydrochloride on nutrient digestibility, environmental N excretion, regulation of skeletal muscle growth, and beta-receptor subtypes in finishing beef steers
… (Actogain, Zoetis, Parsippany, NJ) are growth-promoting technologies that when fed at the end of the finishing period in cattle act as repartitioning agents, redirecting energy toward protein accretion and away from lipid deposition. Despite nearly fifty years of research, several …
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Energy metabolism in skeletal muscle: mechanistic insights into mitochondrial function and growth
Skeletal muscle metabolism is critical to understanding the efficiency of muscle growth for the global meat industry. As such, there are many contributing factors that can influence muscle growth yet there are still basic molecular mechanisms that remain unexplored. Specifically, the involvement of …
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Roles of Zinc in Skeletal Muscle Cells Growth
Zinc deficiency impairs skeletal muscle growth in both humans and animals independently of decreased food intake. Insulin-like growth factor (IGF) is the primary regulator of postnatal muscle growth and there is substantial evidence that the effects of zinc deficiency alter IGF mediated muscle …
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Effects of Extrinsic and Intrinsic Factors on Meat Quality and Muscle Biology of Livestock
… most common factors to improve meat quality and muscle growth. The objective of this thesis is to perform a horizontal comparison of the effects of crude protein levels, breeds, and topsoil on the growth performance, muscle development, and meat quality of livestock, and also a longitudinal …
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Nutritional Strategies to Improve Pig Growth and Performance
Many factors influence the efficiency of muscle growth including genetics, nutrition, and environment. The neonatal period is characterized as a time of rapid growth. Growth rate is reduced during neonatal nutrient restriction possibly due to altered satellite cell activity which can permanently …
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Development of a pericyte-derived extracellular vesicle therapy for the recovery of skeletal muscle mass following immobilization
… declines in protein synthesis and skeletal muscle mass, a condition known as disuse atrophy. Physical therapy is standard practice following disuse atrophy and may be sufficient for complete recovery of muscle mass and function in young individuals. However, the majority of older adults are …
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Altering Muscle Hypertrophy and Fat Accumulation in Myostatin Null Mice
Myostatin is a negative regulator of muscle growth. Loss of myostatin function results in a dramatic phenotype in several species including cattle, mice, dogs and humans. Myostatin mutants exhibit wide-spread hypermuscularity and decreased fat accumulation. Though the phenotype of myostatin mutant …
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Branched-Chain Amino Acid Metabolism in the Neonatal Pig
… signaling function of leucine could increase muscle growth when fed for a longer duration than in previous studies. Neither normal pigs nor low birth weight pigs, which have naturally impaired muscle growth, grew better in response to BCAA supplementation, despite low birth weight pigs …
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