Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1878 for “"murine"”.
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Plant-derived Murine IL-12 and Ricin B-Murine IL-12 Fusions
… sites. Transgenic tobacco plants expressing murine IL-12 were generated and characterized. To ensure stochiometric expression of the two separately encoded, disulfide-linked subunits of IL-12 (p35 and p40), a single-chain form of mouse IL-12 (mIL-12) was utilized. Hairy root cultures, as a …
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Immunotherapy for murine glioma
… (YFP or tdTomato Red) was confirmed in the murine glioma line GL261 in vitro and in vivo. Orthotopic GL261 tumors in immunocompetent C57BL/6J mice were treated with vvDD-IL15Ra-YFP vaccinia virus or vMyx-IL15Ra-tdTr combined with other treatments, including vaccination with GARC-1 peptide (a …
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Pathogenicity of Murine Cytomegalovirus Mutants
… of this study was to identified nonessential murine cytomegalovirus (MCMV) genes involved in pathogenesis in vivo. Our approach to identifyjng these genes consisted of constructing MCMV mutants, and then analyzing these mutants in vitro and in vivo. Recombinant viruses (RV) expressing the …
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INTERACTIONS BETWEEN THE GLYCOSYLATED GAG PROTEIN OF A MURINE LEUKEMIA VIRUS AND MURINE APOBEC3: NOVEL INSIGHTS INTO HOW A MURINE LEUKEMIA VIRUS COUNTERACTS A RESTRICTION FACTOR
… inhibiting reverse transcription. Both HIV and murine leukemia viruses (MuLVs) have evolved mechanisms to evade the action of the APOBEC proteins. HIV encodes the Vif protein which binds to hA3G and facilitates its rapid degradation through the proteasome. The mechanism(s) by which exogenous …
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INTERACTIONS BETWEEN THE GLYCOSYLATED GAG PROTEIN OF A MURINE LEUKEMIA VIRUS AND MURINE APOBEC3: NOVEL INSIGHTS INTO HOW A MURINE LEUKEMIA VIRUS COUNTERACTS A RESTRICTION FACTOR
… inhibiting reverse transcription. Both HIV and murine leukemia viruses (MuLVs) have evolved mechanisms to evade the action of the APOBEC proteins. HIV encodes the Vif protein which binds to hA3G and facilitates its rapid degradation through the proteasome. The mechanism(s) by which exogenous …
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Prolactin signalling in murine hair growth
… JAK-Stat5b pathway. The role of this pathway in murine hair growth was investigated by (i) PRLR gene disrupted mice, (ii) altered circulating prolactin profiles and (iii) impaired PRLR signal transduction with Stat5b gene-disrupted mice. The long (PRLR-L), and two short (PRLR-S2 and PRLR-S3) …
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Structural Analyses of Murine Histocompatibility Antigens
… also detected by a goat antiserum against the murine leukemia virus (MuLV) glycoprotein (gp70) and are therefore closely related to or identical with that viral protein. Further experiments suggest that factors such as viral antigens on the immunizing cells, aging, and general stimulation of …
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ONTOGENESIS OF MURINE NEURAL CREST DERIVATIVES
The neural crest is an epithelial domain within the neural and non-neural ectoderm. This domain is generated along the anterior-posterior axis-giving rise to many different cell types. The key difference between cranial and trunk neural crest is the ability of cranial neural crest to give rise to …
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Immune Mediators of Murine Lyme Arthritis
… aid in the elucidation of mechanisms regulating murine Lyme arthritis and may suggest mechanisms by which human Lyme disease is mediated. (1) We found that the chemokine KC is responsible for neutrophil recruitment and subsequent development of Lyme arthritis and carditis. This was the first …
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Study of the murine RAC2 promoter
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Mechanisms of Immunosuppression in Murine Malaria
An extract was prepared from Plasmodium berghei, NK65C strain, by disrupting P. berghei infected erythrocytes with a Parr bomb disruption cell. This extract was capable of reducing the anti-DNP and SRBC plaque forming cell response of mice intraperitoneally injected with the extract one day prior …
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Mapping the murine leukemia virus genome.
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 1978
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Localization of FC Receptors on Murine Spermatozoa.
Studies on the localization of acrosomal enzymes have shown that a heat stable component in non-immune serum binds to the acrosomal region of spermatozoa of a number of species (Weil and Finkler, 1959; Edwards, 1960). Beck et al. (1962) demonstrated by immunofluorescent techniques that this serum …
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Critical Period for Murine Olfactory Map Formation
Formation of neural circuits in the brain is sensitive to deprivation of neural activity during the critical period. In the last few decades, the critical period has been studied extensively. These studies are primarily focused on the development of receptive fields in the cortex. Mechanisms …
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