Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"multimodality chelator"”.
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Multimodality Somatostatin Analog For Fluorescence-Guided Surgery In Cancer
… affect its imaging properties, we developed a multimodality chelator (MMC) to synthesize a bioactive analog of the NET imaging agent, <sup>68</sup>Ga-DOTA-TOC. The MMC serves as a “radioactive linker” to bridge the near-infrared fluorescent (NIRF) dye IR800 and targeting moiety Tyr-3-octreotide …
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Chemoligand therapy for metastatic castration-resistant prostate cancer
… of the drug built on the general structure of chelator-containing glutamate-ureido-based radiopharmaceuticals for radioligand therapy. After screening taxanes, auristatins, and maytansinoids as candidates for drug development, I conjugated the next-generation microtubule inhibitor monomethyl …