Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"multidrug-resistant tuberculosis"”.
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Spatial frailty modelling for multidrug-resistant Tuberculosis mortality in Namibia
The !Xun San are one of the most marginalised people in the Okongo Community Forest and Conservancy. Traditionally, their economic system largely centred on hunting and gathering. The arrival of the bantu-speaking people in the San’s traditional hunting grounds, however, changed their economic …
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Prevalence of Multidrug-Resistant Tuberculosis in Adults at University Teaching Hospital
Tuberculosis (TB) is an infectious disease caused by There were 14.4 million individuals worldwide living with TB including half a million cases of Multidrug-resistant (MDR) TB in 2006. A most serious aspect of the problem has been the emergence of MDR-TB and extensively drug-resistant (XDR) …
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Prevalence of Multidrug-Resistant Tuberculosis in Adults at University Teaching Hospital
Tuberculosis (TB) is an infectious disease caused by There were 14.4 million individuals worldwide living with TB including half a million cases of Multidrug-resistant (MDR) TB in 2006. A most serious aspect of the problem has been the emergence of MDR-TB and extensively drug-resistant (XDR) …
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A pharmacometric approach to optimal use of second line drugs for multidrug-resistant tuberculosis
… of short course regimens, treatment regimens for multidrug resistant TB (MDR-TB) were long and toxic. Consequently, only approximately half of MDRTB patients completed their treatment. TB dosing guidelines have historically been unrefined with little consideration for …
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The practice of nurses in the prevention of multidrug-resistant tuberculosis at King Cetshwayo district
Submitted in fulfilment of the requirements for the Master of Health Sciences in Nursing, Durban University of Technology, Durban, South Africa, 2017.
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Environmental health recommendations for Multidrug-Resistant Tuberculosis in low- and middle-income countries: a systematic review
… efforts towards the management and prevention of Tuberculosis (TB) having shown some success, Multidrug-Resistant Tuberculosis (MDR-TB) may potentially compromise these endeavours. MDR-TB has the potential to become the most dominant form of TB in low- and middle-income countries (LMICs). The …
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Incidence of aminoglycoside-induced hearing loss in HIV positive and HIV negative multidrug-resistant tuberculosis patients
Aims of the study: To document the incidence and severity of aminoglycoside-induced ototoxicity at Brooklyn Chest Hospital; To determine the prevalence of the 6 known aminoglycoside-induced deafness mutations in the MT-RNR1 gene (A1555G, C1494T, T1095C, T1291C, A827G and 961 indel C) in a cohort of …
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Improved treatment outcomes with bedaquiline when substituted for second-line injectable agents in multidrug-resistant tuberculosis: A retrospective cohort study
… injectable (SLI) intolerance in the treatment of multidrug-resistant tuberculosis (MDR-TB), but the efficacy and safety of this strategy is unknown. Methods We performed a retrospective cohort study to evaluate treatment outcomes for MDR-TB patients who substituted bedaquiline for SLIs. Adults …
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An assessment of Hypoxis hemerocallidea extracts, and actives as natural antibiotic, and immune modulation phytotherapies
… to treat opportunistic infections, such as tuberculosis. The rapid emergence of multidrug-resistant tuberculosis, and extreme drug resistant tuberculosis, in recent years, is a major threat to human health. The treatment of TB, nosocomial bacterial infections, and fungal infections is now a …
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Population pharmacokinetics and pharmacokinetic-pharmacodyamic modeling of antitubercular drugs
… pyrazinamide and ethambutol in 78 patients with tuberculosis were described using non-linear mixed effects modeling. Pharmacodynamic data was comprised of weekly sputum liquid culture (using mycobacterial growth indicator tubes) time to detection results from 144 patients during the first 2 …
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Charakterisierung der Tuberkulosesituation in der Russischen Föderation : Analyse der epidemiologischen Lage und der Probleme in der Tuberkulosekontrolle auf föderaler Ebene und in der Autonomen Republik Tuva
… former Soviet Union suffer from high numbers in tuberculosis prevalences and incidences, the problem of tuberculosis spread is aggravated by rising rates of multidrug resistance. Information for this thesis was gathered by literature research and by analysis of tuberculosis surveillance data from …
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The Consumer of Humans
… have slowed progress in the fight to control tuberculosis globally. Scientists have developed important drugs, such as isoniazid, rifampin, and pyrazinamide, against the disease. But these drugs must be taken for several months, are sometimes ineffective, and can cause debilitating side …
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Screening of South African marine filamentous actinobacteria for antitubercular compounds
Multidrug-resistant tuberculosis (MDR-TB) is a rampant problem across the globe, perpetuated by the current antimicrobial resistance challenge. To lift the burden, novel antitubercular drugs are needed to treat TB more effectively. The filamentous actinobacteria are a viable source of potential …
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Prevalence of multi-drug resistance tuberculosis MDR-TB and associated risk factors among patients in Vhembe Region of Limpopo. South Africa
BACKGROUND: The increasing prevalence of drug-resistant tuberculosis (DR-TB) poses a critical and significant obstacle in the management of tuberculosis (TB) worldwide. This driven by the emergence of multidrug-resistant tuberculosis (MDR-TB) strains and co-infection of TB with human …
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Assessing the effectiveness of Tuberculosis infection control in public healthcarefacilities in the Khomas region
Emerging multidrug-resistant tuberculosis (MDR/XDR-TB) has become a major public health concern, placing millions at risk. Moreover, nosocomial transmission of MDR/XDR-TB places both patients and healthcare workers at an even higher risk. For these reason health facilities in high-risk settings …
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Molecular differentiation of multi-drug resistant mycobacterium tuberculosis complex isolated from three provinces in Zambia
Multidrug-resistant tuberculosis (MDR-TB) is a disease caused by an acid-fast staining pathogenic bacterium, Mycobacterium tuberculosis that is resistant to at least isoniazid (INH) and rifampicin (RIF), the two most potent TB drugs. Drug-resistant tuberculosis poses a significant problem for …
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Molecular differentiation of multi-drug resistant mycobacterium tuberculosis complex isolated from three provinces in Zambia
Multidrug-resistant tuberculosis (MDR-TB) is a disease caused by an acid-fast staining pathogenic bacterium, Mycobacterium tuberculosis that is resistant to at least isoniazid (INH) and rifampicin (RIF), the two most potent TB drugs. Drug-resistant tuberculosis poses a significant problem for …
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Distortion product otoacoustic emissions: towards reliable and valid early identification and monitoring of hearing in adults receiving ototoxic medication
Background: Multidrug-resistant tuberculosis (MDR-TB) patients receive aminoglycosides as part of their treatment. These drugs are ototoxic, and can cause permanent damage to the cochlea, resulting in a debilitating hearing loss, which has a negative impact on an individual's quality of life. Early …
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The impact of undernutrition on tuberculosis prevalence and treatment outcomes in Ethiopia
Introduction: Tuberculosis (TB) is a leading infectious cause of death globally, with an estimated 10.6 million new cases and 1.3 million deaths annually. The emergence of multidrug-resistant tuberculosis (MDR-TB), characterized by resistance to isoniazid and rifampicin, further complicates the …
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The impact of undernutrition on tuberculosis prevalence and treatment outcomes in Ethiopia
Introduction: Tuberculosis (TB) is a leading infectious cause of death globally, with an estimated 10.6 million new cases and 1.3 million deaths annually. The emergence of multidrug-resistant tuberculosis (MDR-TB), characterized by resistance to isoniazid and rifampicin, further complicates the …
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