Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"multiciliogenesis"”.
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Investigating the cytoplasmic role of E2F4 in multiciliogenesis
… have established that E2F4 is necessary for multiciliogenesis in the airway epithelia. Here we show that E2F4 plays two distinct roles in multiciliogenesis. In early stages, it functions in the nucleus to transcriptionally activate centriole biogenesis genes required for cilia formation. …
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3D Nanoscale Architecture and Physiology of the Human Airway Epithelium
… arrangement, and basal body maturation during multiciliogenesis. Furthermore, observations of organelle remodelling were accompanied by single-cell RNA sequencing (scRNA-seq) analysis, which revealed Gene Ontology (GO) enrichment of pathways related to oxidative phosphorylation (OXPHOS), …
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Investigating factors governing cell fate decisions in respiratory epithelium
… unknown, particularly in human lung development. Multiciliogenesis describes the process of specification/differentiation of airway epithelial progenitors/stem cells into mature multiciliated cells (MCCs). Here, I have identified 2 novel transcription factors, Fank1 and Jazf1 which form part of …